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The protective roles of tea tree oil extracts in bovine mammary epithelial cells and polymorphonuclear leukocytes
BackgroundTea tree oil (TTO) plays an important role in antibacterial activity and alleviating the inflammatory responses. Bovine mammary epithelium...
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Organotypic 3D Cell Culture of the Embryonic Lacrimal Gland
Ectodermal organ development, including lacrimal gland, is characterized by an interaction between an epithelium and a mesenchyme. Murine lacrimal... -
Prediction of potential molecular markers of bovine mastitis by meta-analysis of differentially expressed genes using combined p value and robust rank aggregation
Bovine mastitis causes significant economic loss to the dairy industry by affecting milk quality and quantity. Escherichia coli and Staphylococcus...
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Exosomal miR-193b-5p as a regulator of LPS-induced inflammation in dairy cow mammary epithelial cells
Exosomesare a type of extracellular vesicle that act as shuttles, transporting certain genetic information to other cells. MiRNA cargo within...
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Real-life exposure to Fusarium toxins deoxynivalenol and zearalenone triggers apoptosis and activates NLRP3 inflammasome in bovine primary theca cells
Cattle are deemed less susceptible to mycotoxins due to the limited internal exposure resulting from rumen microbiota activity. However, the...
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Modification of Single Cells Within Mouse Mammary Gland Derived Acini via Viral Transduction
The growth of organoid cultures from primary donor tissue is able to recapitulate the original tissue morphology, heterogeneity, and characteristics.... -
Deoxynivalenol Damages Corneal Epithelial Cells and Exacerbates Inflammatory Response in Fungal Keratitis
BackgroundFungal keratitis (FK) is a kind of infectious keratopathy with a high rate of blindness worldwide. Deoxynivalenol (DON) has been proven to...
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Investigation on the suitability of milk-derived primary bovine mammary epithelial cells grown on permeable membrane supports as an in vitro model for lactation
This study aimed to establish an in vitro model for lipid synthesis in primary bovine mammary epithelial cells (pbMECs) extracted from milk and...
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Characterization of immortalized ovarian epithelial cells with BRCA1/2 mutation
We aimed to elucidate the mechanism underlying carcinogenesis by comparing normal and BRCA1/2- mutated ovarian epithelial cells established via Sendai...
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Visualizing Dynamic Changes During TGF-β-Induced Epithelial to Mesenchymal Transition
Epithelial to mesenchymal transition (EMT) is crucial during embryonic development, tissue fibrosis, and cancer progression. Epithelial cells that... -
Blood neutrophil extracellular traps: a novel target for the assessment of mammary health in transition dairy cows
BackgroundMammary health is important for transition dairy cows and has been well recognized to exert decisive effects on animal welfare. However,...
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RUNX transcription factors are essential in maintaining epididymal epithelial differentiation
Apart from the androgen receptor, transcription factors (TFs) that are required for the development and formation of the different segments of the...
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Evolution of gene expression signature in mammary gland stem cells from neonatal to old mice
During the lifetime of females, mammary epithelial cells undergo cyclical expansion and proliferation depending on the cyclical activation of mammary...
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3D Cell Culture: Techniques For and Beyond Organoid Applications
In the rapidly evolving landscape of cell biology and biomedical research, three-dimensional (3D) cell culture has contributed not only to the... -
Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary cancer
BackgroundPremenopausal women diagnosed with breast cancer often face aggressive chemotherapy resulting in infertility. Tamoxifen (TAM) is a...
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Bacterial Community Profile of Bovine Mastitis Infected Dairy Cow Milk by 16S rRNA Amplicon Sequencing
The prevalence of Bovine mastitis, an important disease of cow, causing huge economic loss in dairy industries, was tested in cows and other types of...
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Develo** ovine mammary terminal duct lobular units have a dynamic mucosal and stromal immune microenvironment
The human breast and ovine mammary gland undergo striking levels of postnatal development, leading to formation of terminal duct lobular units...
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Using of NMR Milk Metabolomics to Evaluate Mammary Gland Health Status in Dairy Cows
Objectives. Milk of mammal origin is an important food in the diet during infancy as well as in adulthood. It contains lipids, proteins,... -
Assessment of Breast Cancer Stem Cell Activity Using a Spheroid Formation Assay
Evidence is emerging that cancer cells are arranged as a hierarchy that spans from stem cells to lineage-restricted progenitor cells. The recent... -
Different miRNA contents between mammary epithelial cells and milk fat globules: a random or a targeted process?
MicroRNAs (miRNAs) are small noncoding RNAs present in milk-derived extracellular vesicles and milk fat globules (MFG). Nucleic acid content between...