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Assays for Studying Pseudomonas aeruginosa Secreted Proteases
Proteolytic activity plays an essential role in Pseudomonas aeruginosa adaptation and survival in challenging environments, including the infection...
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Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses
The most frequent fetal birth defect associated with prenatal Zika virus (ZIKV) infection is brain calcification, which in turn may potentially...
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Identification and characterization of acid and alkaline phosphatases and protein phosphatases in L. catesbeianus tail during metamorphosis
Amphibian metamorphosis is a tightly regulated transformation involving the participation of hormones and other biomolecules in cell death and tail...
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Metarhizium robertsii protease and conidia production, response to heat stress and virulence against Aedes aegypti larvae
Nutritional factors exert significant influence on the growth of entomopathogenic fungi, one of the main agents employed commercially in the...
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Acetylproteomics analyses reveal critical features of lysine-ε-acetylation in Arabidopsis and a role of 14-3-3 protein acetylation in alkaline response
Lysine-ε-acetylation (Kac) is a post-translational modification (PTM) that is critical for metabolic regulation and cell signaling in mammals....
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Protease Enzymes: Highlights on Potential of Proteases as Therapeutics Agents
In the era of advancement of biotechnology and molecular biology, the structure, catalytic site specification, role in biochemical processes, and...
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Structural-genetic insight and optimization of protease production from a novel strain of Aeromonas veronii CMF, a gut isolate of Chrysomya megacephala
Structural-genetic characterization of protease producing genes and enzymes from microbial sources are seldom appreciated despite having its...
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Extracellular proteases and laccases produced by Pleurotus ostreatus PoB: the effects of proteases on laccase activity
Laccases are enzymes produced by plants and white rot fungi, such as Pleurotus ostreatus , with industrial applications. Fungal laccases have been...
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Enzyme promiscuity in natural environments: alkaline phosphatase in the ocean
Alkaline phosphatase (APase) is one of the marine enzymes used by oceanic microbes to obtain inorganic phosphorus (P i ) from dissolved organic...
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Effects of Different Plant Species on the Chemical and Microbial Properties of Coastal Saline-Alkaline Soils in Southeast China
The study aimed to explore the biological amendment effect of different plants on the coastal saline-alkali soils. The different plant species were...
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Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells
The ubiquitin protease pathway plays important role in human bone marrow-derived mesenchymal stem cell (hBMSC) differentiation, including...
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Effect of Different Classes of Proteases on the Techno-Functional Properties of Pea Protein Isolates
AbstractThe effect of four enzyme preparations: bacillolysin, agroprot, protozyme and protozyme C (Russia) on solubility, emulsifying activity,...
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Kinetics of growth and co-production of amylase and protease in novel marine actinomycete, Streptomyces lopnurensis KaM5
Amylases and proteases are among the industrially most important enzymes for food processing, animal feed, brewing, starch processing, detergents,...
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Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis
Proteins expressed by the paired box gene 9 (PAX9) and Msh Homeobox 1 (MSX1) are intimately involved in tooth development (odontogenesis). The...
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Effect of fasting on compensatory growth and digestive enzymatic activity of freshwater prawn post larvae (Macrobrachium rosenbergii) during its culture in biofloc
During 75 days, the fasting/cyclic refeeding effect was evaluated on survival, growth, and digestive enzymatic activity in the hepatopancreas of...
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Synthesis, In Vitro, and In Silico Studies of N-(Substituted-Phenyl)-3-(4-Phenyl-1-Piperazinyl)propanamides as Potent Alkaline Phosphatase Inhibitors
AbstractIn the present research work, a new series of N -(substituted-phenyl)-3-(4-phenyl-1-piperazinyl)propanamides were synthesized. The synthesis...
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Computational investigation of drug bank compounds against 3C-like protease (3CLpro) of SARS-CoV-2 using deep learning and molecular dynamics simulation
Blocking the main replicating enzyme, 3 Chymotrypsin-like protease (3CL pro ) is the most promising drug development strategy against the SARS-CoV-2...
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Alkaliphilic, Alkalitolerant Microorganisms
Alkaliphilic microorganisms are those microbes that require alkaline pH for growth with optimum growth at pH 9.0. They cannot grow or grow only...
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Alkaline Protease: A Tool to Manage Solid Waste and Its Utility in Detergent Industry
Management of solid waste is an issue of contemporary interest worldwide. Nowadays most of the solid wastes are disposed on the land, and various...
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Bioprospection of Endophytic Fungi for Extracellular Enzymes
Endophytes include a family of microorganisms that grow asymptomatically within the host plants. They positively influence the growth and development...