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Landscape of global urban environmental resistome and its association with local socioeconomic and medical status
Antimicrobial resistance (AMR) poses a critical threat to global health and development, with environmental factors—particularly in urban...
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Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg.
A large number of infections are caused by Gram-positive and Gram-negative multi-resistant bacteria worldwide, adding up to a figure of around...
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Lys–Arg mutation improved the thermostability of Bacillus cereus neutral protease through increased residue interactions
Neutral proteases have broad application as additives in modern laundry detergents and therefore, thermostability is an integral parameter for...
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Environmental microbiome diversity and stability is a barrier to antimicrobial resistance gene accumulation
When antimicrobial resistant bacteria (ARB) and genes (ARGs) reach novel habitats, they can become part of the habitat’s microbiome in the long term...
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Oxytetracycline and heavy metals promote the migration of resistance genes in the intestinal microbiome by plasmid transfer
Horizontal gene transfer (HGT) has been considered the most important pathway to introduce antibiotic resistance genes (ARGs), which seriously...
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Use of Group-Specific Reagents in Active Site Functional Group Elucidation II: Asp, Glu, Arg, Lys, and His Residues
The use of group-specific reagents for acidic and basic amino acid residue side chain have been discussed. The reagents include carbodiimide,...
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Dietary supplementation with l-arginine between days 14 and 25 of gestation enhances NO and polyamine syntheses and the expression of angiogenic proteins in porcine placentae
Dietary supplementation with 0.4 or 0.8% l -arginine (Arg) to gilts between days 14 and 25 of gestation enhances embryonic survival and vascular...
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Gut microbiome variations in Rhinopithecus roxellanae caused by changes in the environment
BackgroundThe snub-nosed monkey ( Rhinopithecus roxellanae ) is an endangered animal species mainly distributed in China and needs to be protected....
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Single-Base Editing in the Arabidopsis SUMO Conjugating Enzyme by Adenine Base Edition and Screening for a Rare Editing Event
SUMO conjugation is an essential process that regulates development and supports plant adaptation to environmental stress. We previously found that a...
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Sapium glandulosum (L.) Morong Sapindaceae
Hippomane glandulosa L.; Excoecaria aerea (Klotzsch ex Müll.Arg.) Müll.Arg.; Excoecaria biglandulosa var. aubletiana (Müll.Arg.) Müll.Arg.;...
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Design and evaluation of tadpole-like conformational antimicrobial peptides
Antimicrobial peptides are promising alternatives to conventional antibiotics. Herein, we report a class of “tadpole-like” peptides consisting of an...
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Dietary L-arginine supplementation during days 14–25 of gestation enhances aquaporin expression in the placentae and endometria of gestating gilts
This study tested the hypothesis that dietary L-arginine (Arg) supplementation to pregnant gilts enhanced the expression of water channel proteins...
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Inhibition Profiling of Bestatin Against the Aminopeptidase B: in silico and in vitro Approach
AbstractInhibitors of aminopeptidase B are potential drugs for the treatment of tumor angiogenesis, invasion and metastasis. Immunomodifier bestatin...
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The occurrence of antimicrobial residues and antimicrobial resistance genes in urban drinking water and sewage in Southern Brazil
Antimicrobial resistance (AMR) is currently discussed as an important issue worldwide, and the presence of antimicrobial residues (ARs) and...
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Phenylalanine as an effective stabilizer and aggregation inhibitor of Bacillus amyloliquefaciens alpha-amylase
Aromatic compounds are known anti-amyloid aggregates. Their effect on amorphous aggregates of proteins is, however, less studied. We chose aromatic...
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Genome-Wide Identification of MabHLH Transcription Factors Family Response to Magnesium Deficiency Stress in Banana (Musa paradisiaca AA)
Banana is an important tropical fruit belonging to the Musa family, which is susceptible to nutritional deficiency symptoms during cultivation. Due...
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Characterization and Abundance of Plasmid-Dependent Alphatectivirus Bacteriophages
Antimicrobial resistance (AMR) is a major public health threat, exacerbated by the ability of bacteria to rapidly disseminate antimicrobial...
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Novel Antiproliferative Tripeptides Inhibit AP-1 Transcriptional Complex
Among pro-tumor transcriptional complexes, activating protein-1 (AP-1) controls the expression of key oncogenes in cancer. Therefore, avenues for...
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Characterization of the soil resistome and mobilome in Namib Desert soils
The study of the soil resistome is important in understanding the evolution of antibiotic resistance and its dissemination between the clinic and the...
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Evaluation of the predictive values of elevated serum l-homoarginine and dimethylarginines in preeclampsia
l -homoarginine (hARG) is involved in nitric oxide biosynthesis, but its role and concentration in preeclampsia (PE) have not been fully revealed. The...
