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Promoting Pro-Endocrine Differentiation and Graft Maturation Following Surgical Resection of the Mouse Pancreas
Type 1 diabetes (T1D) is an autoimmune disease, where insulin-producing β-cells in the pancreas are inappropriately recognized and destroyed by... -
Left-ventricular hypertrophy in 18-month-old donor rat hearts was not associated with graft dysfunction in the early phase of reperfusion after cardiac transplantation–gene expression profiling
The use of hearts with left-ventricular (LV) hypertrophy (LVH) could offer an opportunity to extend the donor pool for cardiac transplantation. We...
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Rabbit Surgery Protocol for End-to-End and End-to-Side Vascular Graft Anastomosis
Preclinical testing in animal model is a required stage of vascular device development. Among small animal models, rabbits provide vasculature with... -
Evaluation of anatomical and histological characteristics of human peripheral nerves: as an effort to develop an efficient allogeneic nerve graft
Management of peripheral nerve defects is a complicated problem in clinical contexts. Autologous nerve grafting, a gold standard for surgical...
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Small extracellular vesicles from human adipose-derived mesenchymal stromal cells: a potential promoter of fat graft survival
BackgroundSmall extracellular vesicles (sEVs) with genetic information secreted by cells play a crucial role in the cellular microenvironment. In...
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A novel RIP1/RIP3 dual inhibitor promoted OPC survival and myelination in a rat neonatal white matter injury model with hOPC graft
BackgroundThe dual inhibitors of receptor interacting protein kinase-1 and -3 (RIP1 and RIP3) play an important role in cell death processes and...
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Adipose-derived cellular therapies prolong graft survival in an allogenic hind limb transplantation model
BackgroundThe long-term survival after vascularized composite allotransplantation (VCA) is often limited by systemic rejection as well as the adverse...
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Gender medicine in corneal transplantation: influence of sex mismatch on rejection episodes and graft survival in a prospective cohort of patients
To evaluate the effect of donor-to-recipient sex mismatched (male donor corneas to female recipients) on the incidence of rejection episodes and...
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MiR-181a and -b expression in acute lymphoblastic leukemia and its correlation with acute graft-versus-host disease after hematopoietic stem cell transplantation, COVID-19 and torque teno viruses
Acute lymphoblastic leukemia (ALL), a malignant transformation and proliferation of the lymphoid line of blood cells, is characterized by chromosomal...
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Cyclosporine A and IFNγ licencing enhances human mesenchymal stromal cell potency in a humanised mouse model of acute graft versus host disease
Immunosuppressive ability in human MSC donors has been shown to be variable and may be a limiting factor in MSC therapeutic efficacy in vivo. The...
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Development of local vancomycin delivery system from fibrin gel to prevent Staphylococcus aureus biofilms graft infection
Prosthetic vascular graft infection is one of the most severe vascular surgery complications. Fibrin gel (FG) has many useful characteristics as...
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Histological Investigation of the Compatibility of Prunus spinosa as Interstock with Almond Cultivars
The aim of this study was to determine the early graft compatibility of ‘Ferraduel’, ‘Ferragnes’, ‘Makako’, ‘Tarraco’ and ‘Vairo’ almond cultivars...
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Synthesis and characterization of multiarm star-shaped water-soluble graft copolymer through atom transfer radical polymerization of acrylamide initiated from bio-based lignin macroinitiator
In this research, two types of lignin-based macroinitiators were prepared using α-bromoisobutyrylation reaction. Hydroxyl groups (OH) of lignin were...
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Metabolite profiling during graft union formation reveals the reprogramming of primary metabolism and the induction of stilbene synthesis at the graft interface in grapevine
BackgroundGrafting with rootstocks is essential for the culture of many perennial fruit crops and is increasing being used in the production of...
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Physio-Biochemical and Growth Response of Contrasting Reciprocal Grafting in Citrus Under Water Deficit and Rehydration
The present study investigated how contrasting citrus rootstocks, drought susceptible, Citrus jambhiri Lush cv . Jatti Khatti (JK) and...
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miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function through exosome-mediated mechanisms in vitro and attenuates vein graft neointimal formation in vivo
BackgroundThe aim of this study was to determine whether the combination of MSC implantation with miRNA-126-3p overexpression would further improve...
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Involvement of ischemia-driven 5-lipoxygenase-resolvin-E1-chemokine like receptor-1 axis in the resolution of post-coronary artery bypass graft inflammation in coronary arteries
AimsExpression status of pro-resolvin lipid mediators (PLM) and receptors in the post-Coronary artery bypass grafting (CABG) coronary arteries are...
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Developmental stage of transplanted neural progenitor cells influences anatomical and functional outcomes after spinal cord injury in mice
Neural progenitor cell (NPC) transplantation is a promising therapeutic strategy for replacing lost neurons following spinal cord injury (SCI)....
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Wnt/β-catenin signaling mediates the abnormal osteogenic and adipogenic capabilities of bone marrow mesenchymal stem cells from chronic graft-versus-host disease patients
Chronic graft-versus-host disease (cGVHD) is the main cause of non-relapse mortality after allogeneic hematopoietic stem cell transplantation...
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Non-HLA angiotensin-type-1 receptor autoantibodies mediate the long-term loss of grafted neurons in Parkinson’s disease models
BackgroundClinical trials have provided evidence that transplants of dopaminergic precursors, which may be replaced by new in vitro stem cell...