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Exploring virulence factors of Helicobacter pylori isolated from gastric biopsy
BackgroundHelicobacter pylori ( H. pylori ) colonizes human gastric mucosa and is classified as class one carcinogenic bacteria. In this regard, this...
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Optimization and evaluation of a multiplex PCR assay for detection of Staphylococcus aureus and its major virulence genes for assessing food safety
Staphylococcus aureus is a natural commensal microflora of humans which causes opportunistic infections due to its large arsenal of exotoxins,...
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Drug repositioning: doxazosin attenuates the virulence factors and biofilm formation in Gram-negative bacteria
AbstractThe resistance development is an increasing global health risk that needs innovative solutions. Repurposing drugs to serve as anti-virulence...
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Epidemiological and clinicopathological findings in 15 fatal outbreaks of salmonellosis in dairy calves and virulence genes in the causative Salmonella enterica Typhimurium and Dublin strains
Salmonella enterica is a major food-borne pathogen that affects cattle-rearing systems worldwide. Little information is available on the epidemiology...
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Exploring Nocardia’s ecological spectrum and novel therapeutic frontiers through whole-genome sequencing: unraveling drug resistance and virulence factors
Nocardia farcinica is the leading pathogen responsible for nocardiosis, a life-threatening infection primarily affecting immunocompromised patients....
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Uropathogenic bacteria and deductive genomics towards antimicrobial resistance, virulence, and potential drug targets
Urinary tract infections (UTIs) are among the most prevalent bacterial infections affecting people in inpatient and outpatient settings. The current...
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Proportion of toxin and non-toxin virulence factors of Staphylococcus aureus isolates from diabetic foot infection: a systematic review and meta-analysis
BackgroundStaphylococcus aureus isolates are the leading cause of diabetic foot infections (DFIs). Identification of specific virulence factors of S....
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Clonal Diversity, Antimicrobial Susceptibility and Presence of Genes Encoding Virulence Factors in Staphylococcus aureus Strains Isolated from Cut Wound Infections
The aim of the study was to evaluate the clonal relatedness and antimicrobial susceptibility in 52 Staphylococcus aureus strains isolated from cut...
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The phase variation between wrinkly and smooth colony phenotype affects the virulence of Vibrio parahaemolyticus
Vibrio parahaemolyticus , the causative agent of seafood-associated gastroenteritis, undergoes wrinkly and smooth colony switching on the plate. The...
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A correlation study between virulence factors and multidrug resistance among clinical isolates of Proteus mirabilis
Treatment of Proteus mirabilis infections is a challenge due to the high abundance of virulence factors and the high intrinsic resistance to...
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Spectrum of ctxB genotypes, antibiogram profiles and virulence genes of Vibrio cholerae serogroups isolated from environmental water sources from Odisha, India
BackgroundThe present study reports on the comprehensive analysis of Vibrio cholerae O1 and non-O1/non-O139 serogroups isolated from environmental...
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Yearly changes in virulence of Phakopsora pachyrhizi isolates in Paraguay
Asian soybean rust (ASR), caused by the pathogen Phakopsora pachyrhizi , is one of the most notable soybean diseases in Paraguay because of the...
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Investigation on biofilm composition and virulence traits of S. pseudintermedius isolated from infected and colonized dogs
Staphylococcus pseudintermedius , which is part of the skin microbiome of dogs, causes a variety of opportunistic infections. These infections may...
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Molecular ty** and virulence characteristics of Escherichia coli strains isolated from hospital and community acquired urinary tract infections
BackgroundThe main causes of hospital- and community-acquired urinary tract infections (UTIs) are a group of Escherichia coli ( E. coli ) strains with...
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Candida albicans in the oral cavities of pets: biofilm formation, putative virulence, antifungal resistance profiles and classification of the isolates
The study aimed to investigate Candida albicans presence, antifungal resistance, biofilm formation, putative virulence genes, and molecular...
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Exogenous indole modulates several CpxRA-mediated virulence-related parameters of Edwardsiella piscicida in vitro
Indole signaling has been regarded as a promising target to control aquatic diseases. However, the relationship between exogenous indole and the...
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Evaluation of the effect of ibuprofen in combination with ciprofloxacin on the virulence-associated traits, and efflux pump genes of Pseudomonas aeruginosa
Biofilm formation and antibiotic efflux are two determinant factors in the development of drug resistance phenotype by Pseudomonas aeruginosa. ...
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Bacterial volatile organic compounds attenuate pathogen virulence via evolutionary trade-offs
Volatile organic compounds (VOCs) produced by soil bacteria have been shown to exert plant pathogen biocontrol potential owing to their strong...
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Antibiotic resistance, phylogenetic ty**, and virulence genes profile analysis of uropathogenic Escherichia coli isolated from patients in southern Iraq
Of the most common infectious diseases that occur mainly by uropathogenic Escherichia coli (UPEC) is urinary tract infections (UTIs). The purpose of...
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Discovery of psoralen as a quorum sensing inhibitor suppresses Pseudomonas aeruginosa virulence
AbstractP seud omon as aeruginosa is a common opportunistic pathogen with growing resistance and presents heightened treatment challenges. Quorum...