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CCN2 (Cellular Communication Network factor 2) in the bone marrow microenvironment, normal and malignant hematopoiesis
CCN2, formerly termed Connective Tissue Growth Factor, is a protein belonging to the Cellular Communication Network (CCN)-family of secreted...
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Role of Cholesterol and its Biosynthetic Precursors on Membrane Organization and Dynamics: A Fluorescence Approach
Cholesterol is the most representative sterol present in membranes of higher eukaryotes, and is the end product of a long and multistep biosynthetic...
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Uncovering the mechanisms underlying pear leaf apoplast protein-mediated resistance against Colletotrichum fructicola through transcriptome and proteome profiling
Pear anthracnose, caused by the fungus Colletotrichum fructicola , is a devastating disease for the pear industry. The apoplast, an extracellular...
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A case report of a rapid development of fetal anasarca in a canine pregnancy at term
A 5-year-old healthy pluriparous pregnant Flat-coated Retriever bitch was monitored by ultrasound on post-ovulation days 30 and 57: no deviation from...
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Tissue-Material Integration and Biostimulation Study of Collagen Acellular Matrices
Background:Breast reconstruction after mastectomy using silicone implants is a surgical procedure that occasionally leads to capsular contracture...
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LC‒MS/MS and transcriptome analyses reveal saliva components of the seed-feeding truebug Pyrrhocoris apterus
Saliva secretion is essential for successful feeding by piercing–sucking insects. Despite extensive studies of the saliva composition of phloem- and...
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Herpesvirus Infections of the Central Nervous System
Double-stranded DNA herpesviruses are capable of establishing latency and reactivation. They are subdivided into eight human herpesviruses (HHVs):...
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Assembly of Cellular Nanomachines
Figure: Schematic diagram and the EM micrograph of the self-assembled t-/v-SNARE ring complex established when v-SNARE-associated membrane interacts...
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Kinetic mechanisms by which nickel alters the calcium (Ca2+) transport in intact rat liver
In the present work, the multiple-indicator dilution (MID) technique was used to investigate the kinetic mechanisms by which nickel (Ni 2+ ) affects...
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Extracellular Vesicles: The Challenges on the Way and Engineering Perspectives
Extracellular vesicles (EVs) are found in every body fluid and are known to be released by every human cell. So far, EVs have been classified into...
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Specificity of H2O2 signaling in leaf senescence: is the ratio of H2O2 contents in different cellular compartments sensed in Arabidopsis plants?
Leaf senescence is an integral part of plant development and is driven by endogenous cues such as leaf or plant age. Developmental senescence aims to...
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Space habitats for bioengineering and surgical repair: addressing the requirement for reconstructive and research tissues during deep-space missions
Numerous technical scenarios have been developed to facilitate a human return to the Moon, and as a testbed for a subsequent mission to Mars. Crews...
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Elevated SFXN2 limits mitochondrial autophagy and increases iron-mediated energy production to promote multiple myeloma cell proliferation
Human sideroflexin 2 (SFXN2) belongs to the SFXN protein family, which is a mitochondrial outer membrane protein involved in mitochondrial iron...
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Lung development and regeneration: newly defined cell types and progenitor status
The lung is the most critical organ of the respiratory system supporting gas exchange. Constant interaction with the external environment makes the...
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The role of Aquaporins in tumorigenesis: implications for therapeutic development
Aquaporins (AQPs) are ubiquitous channel proteins that play a critical role in the homeostasis of the cellular environment by allowing the transit of...
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Stochastic biological system-of-systems modelling for iPSC culture
Large-scale manufacturing of induced pluripotent stem cells (iPSCs) is essential for cell therapies and regenerative medicines. Yet, iPSCs form large...
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Building a Co-ordinated Musculoskeletal System: The Plasticity of the Develo** Skeleton in Response to Muscle Contractions
The skeletal musculature and the cartilage, bone and other connective tissues of the skeleton are intimately co-ordinated. The shape, size and...
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Ceratonia siliqua (Carob) extract improved in vitro development of vitrified-warmed mouse germinal vesicle oocytes: assessment of possible mechanism
Oocyte banking is a vital step for safekee** and spreading genetic resources of animals. It is also used for fertility preservation of human....
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Advances in protein glycosylation and its role in tissue repair and regeneration
After tissue damage, a series of molecular and cellular events are initiated to promote tissue repair and regeneration to restore its original...
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Repurposing of approved antivirals against dengue virus serotypes: an in silico and in vitro mechanistic study
Dengue is an emerging, mosquito-borne viral disease of international public health concern. Dengue is endemic in more than 100 countries across the...
