Search
Search Results
-
Tissue Engineering to Study and Treat Cardiovascular Calcification
Mineralization of the cardiovascular system is a complex condition whose presence strongly predicts cardiovascular mortality and results in a high...
-
Adipokines, adiposity, and atherosclerosis
Characterized by a surplus of whole-body adiposity, obesity is strongly associated with the prognosis of atherosclerosis, a hallmark of coronary...
-
Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation
Histopathological studies have revealed key processes of atherosclerotic plaque thrombosis. However, the diversity and complexity of lesion types...
-
Influence of the Gut Microbiome on Cardiovascular Health and Hypertension
Cardiovascular diseases are characterized by high rates of morbidity and mortality. Microbiota are closely associated with cardiovascular disease....
-
Concentration-Dependent Effects of Boric Acid on Osteogenic Differentiation of Vascular Smooth Muscle Cells
Vascular calcification can be triggered by oxidative stress and inflammation. Although boron possesses antioxidant and anti-inflammatory properties,...
-
Application of OpenArray RT-qPCR for identification of microRNA expression signatures of lower extremity artery disease
Lower extremity artery disease (LEAD) is an underestimated chronic vascular disease caused by the formation of atherosclerotic plaques in the lower...
-
Exosomal miR-129 and miR-342 derived from intermittent hypoxia-stimulated vascular smooth muscle cells inhibit the eIF2α/ATF4 axis from preventing calcified aortic valvular disease
This study aims to elucidate the role of miR-129/miR-342 loaded in exosomes derived from vascular smooth muscle cells (VSMCs) stimulated by...
-
GAS5/METTL14/ESR1 genetic variants are related to the susceptibility of coronary heart disease
The prevention and treatment of coronary heart disease (CHD) is a difficult problem to be solved urgently. Genetic factors play a crucial role in CHD...
-
MIA3 promotes the degradation of GSH (glutathione) by binding to CHAC1, thereby promoting the progression of hepatocellular carcinoma
MIA3 (melanoma inhibitory active protein 3)/TANGO1 (Golgi transporter component protein) plays an important role in the initiation, development, and...
-
Biochemical Clusters as Substitutes of Bone Biopsies in Kidney Transplant Patients
Bone and mineral metabolism abnormalities are frequent in kidney transplant recipients and have been associated with cardiovascular morbidity. The...
-
Dog models of human atherosclerotic cardiovascular diseases
Cardiovascular diseases (CVD) are one of the leading causes of death worldwide. Eighty-five percent of CVD-associated deaths are due to heart attacks...
-
Prognostic impact of the atherogenic index of plasma in type 2 diabetes mellitus patients with acute coronary syndrome undergoing percutaneous coronary intervention
BackgroundThe association of the atherogenic index of plasma (AIP), an emerging lipid index that can predict the risk for cardiovascular disease,...
-
Oxysterols in Vascular Cells and Role in Atherosclerosis
Atherosclerosis is a major cardiovascular complication of diseases associated with elevated oxidative stress such as type 2 diabetes and metabolic...
-
Unravelling the role of cathepsins in cardiovascular diseases
Lysosomal cathepsins as a regulatory medium have been assessed as potential therapeutic targets for the treatment of various cardiac diseases such as...
-
Macrophage polarization and metabolism in atherosclerosis
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty deposits in the inner walls of vessels. These plaques...
-
Role of sirtuins in attenuating plaque vulnerability in atherosclerosis
Atherosclerosis is characterized by the development of intimal plaque, thrombosis, and stenosis of the vessel lumen causing decreased blood flow and...
-
Decoding the transcriptome of calcified atherosclerotic plaque at single-cell resolution
Atherogenesis involves an interplay of inflammation, tissue remodeling and cellular transdifferentiation (CTD), making it especially difficult to...
-
Heart Valve Disease
This chapter was designed to provide the reader with a brief overview of the current treatment options for human heart valve disease. Major topics of...
-
Association of ACE gene polymorphisms with in-stent restenosis by stent type (biomime, supraflex, xience)
IntroductionAngiotensin Converting Enzyme or ACE is an exo-peptidase that causes the conversion of angiotensin I to angiotensin II, vasoconstriction,...
-
Imaging retinal microvascular manifestations of carotid artery disease in older adults: from diagnosis of ocular complications to understanding microvascular contributions to cognitive impairment
Carotid artery stenosis (CAS) is a consequence of systemic atherosclerotic disease affecting the aging populations of the Western world. CAS is...
