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Evaluating the use of novel atherogenicity indices and insulin resistance surrogate markers in predicting the risk of coronary artery disease: a case‒control investigation with comparison to traditional biomarkers
BackgroundDue to the contribution of coronary artery disease (CAD) to serious cardiovascular events, determining biomarkers that could robustly...
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Effects of weight change on apolipoprotein B-containing emerging atherosclerotic cardiovascular disease (ASCVD) risk factors
Background and aimsNon-high-density (HDL)-cholesterol, low-density lipoprotein (LDL)-particle number, apolipoprotein B, lipoprotein(a) (Lp(a)), and...
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Sex difference in the relationship of the Atherogenic index of plasma with coronary artery lesions in diabetes: a cross-sectional study
BackgroundCoronary artery disease (CAD) tends to progress more rapidly in the type 2 diabetes mellitus (T2DM) population and may be associated with...
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Atherogenic index of plasma is related to coronary atherosclerotic disease in elderly individuals: a cross-sectional study
BackgroundDyslipidaemia plays an important role in coronary atherosclerotic disease (CAD). The relationship between the atherogenic index of plasma...
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Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health
Obesity is a leading cause of morbidity and mortality globally. While the prevalence of obesity has been increasing, the incidence of its related...
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Decreased plasma lipid levels in a statin-free Danish primary health care cohort between 2001 and 2018
BackgroundLipid levels in blood have decreased considerably during the past decades in the general population partly due to use of statins. This...
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Oxidized Low-Density Lipoprotein: Preparation, Validation, and Use in Cell Models
Lipoproteins in plasma are constituted by the least dense chylomicron, very-low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and...
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Non-fasting lipids detection and their significance in pregnant women
BackgroundThe majority of pregnant women present an increase in lipids. To investigate the influence of the non-fasting state in the lipid and...
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Common mechanisms underlying diabetic vascular complications: focus on the interaction of metabolic disorders, immuno-inflammation, and endothelial dysfunction
Diabetic vascular complications (DVCs), including macro- and micro- angiopathy, account for a high percentage of mortality in patients with diabetes...
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Lipids and Cardiovascular Disease Risks with a Focus on Dairy Foods
Cardiovascular diseases (CVD) remain a major cause of death and morbidity worldwide and dietary guidelines aim to restrict the intake of saturated...
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Efficacy of a nutraceutical combination on lipid metabolism in patients with metabolic syndrome: a multicenter, double blind, randomized, placebo controlled trial
BackgroundNutraceuticals represent a new therapeutic frontier in the treatment of metabolic syndrom (MetS) and related cardiovascular risk factors....
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Elevated postprandial triglyceride-rich lipoproteins in patients with diabetes and stable coronary artery disease correlated with early renal damage and systemic inflammation
BackgroundDyslipidaemia is key in the development of coronary heart disease (CHD) in patients with diabetes mellitus (DM). Accumulated evidence...
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Systems Biology for Metabolic Disorder and Disease
The simplistic approach frequently used in biological sciences is no longer sufficient if we want to research complicated multi-factorial illnesses...
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Rho A/ROCK1 signaling-mediated metabolic reprogramming of valvular interstitial cells toward Warburg effect accelerates aortic valve calcification via AMPK/RUNX2 axis
The aberrant differentiation of valvular interstitial cells (VICs) to osteogenic lineages promotes calcified aortic valves disease (CAVD), partly...
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Potential metabolic biomarkers of critical limb ischemia in people with type 2 diabetes mellitus
IntroductionType 2 diabetes mellitus (T2DM) is a significant risk factor for the development of critical limb ischemia (CLI), the most advanced stage...
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Food and Plant Bioactives for Reducing Cardiovascular Disease Risk
Cardiovascular diseases (CVDs) are the leading cause of mortality and disability worldwide, taking an estimated 17.9 million lives each year. The...
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Non-HDL as a Valid Surrogate Marker of Small Dense LDL in a Young Indian Population
Small dense (sd) LDL is a significant independent risk factor for premature coronary artery disease (CAD). Unfortunately, its estimation is not...
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The sensibility of the new blood lipid indicator——atherogenic index of plasma (AIP) in menopausal women with coronary artery disease
BackgroundDyslipidemia is a key driver of coronary artery disease (CAD) development. This study aimed to determine whether the atherogenic index of...
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Non-invasive skin cholesterol testing: a potential proxy for LDL-C and apoB serum measurements
BackgroundLipid management is the first line of treatment for decreasing the incidence of cardiovascular events in patients with coronary heart...
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Measured Versus Calculated Small Dense LDL-Cholesterol and Cardiometabolic Traits in a South African Population
Small-dense low density lipoprotein (sdLDL) is increasingly viewed as a marker for evaluating atherogenic risk, however its clinical uptake is...
