Search
Search Results
-
Human interstitial cellular model in therapeutics of heart valve calcification
Calcific aortic valve disease is a common, severe heart condition that is currently with no proven, effective drug treatment and requires a surgical...
-
Bioprosthetic Heart Valves: From a Biomaterials Perspective
For the past 50+ years, the heart valve replacement (HVR) industry has gone through multiple growth phases in terms of innovation and market growth,...
-
Asymptomatic heart valve dysfunction in healthy middle-aged companion dogs and its implications for cardiac aging
Heart disease is the leading cause of death in the USA, accounting for about one in every four deaths. Age is the greatest risk factor for heart...
-
Failure in Cardiac Action: Comparing Humans, Dogs, Cats, and Horses
The heart is a central organ kee** the blood flow going, thereby providing oxygenation of peripheral tissues. An overview is given here on the most...
-
Vasovagal tonus index (VVTI) as an indirect assessment of remission status in canine multicentric lymphoma undergoing multi-drug chemotherapy
Vasovagal tonus index (VVTI) is an indirect measure of heart rate variability and may serve as a marker of disease severity. Higher heart rate...
-
New biomarkers for primary mitral regurgitation
BackgroundMitral regurgitation is a frequent valvular heart disease affecting around 2.5 % of the population with prevalence directly related to...
-
Muscleblind-like 1 is required for normal heart valve development in vivo
BackgroundDevelopment of the valves and septa of the heart depends on the formation and remodeling of the endocardial cushions in the...
-
Arterial pulse wave propagation velocity in healthy dogs by pulse wave Doppler ultrasound
The aim of this study was to prospectively evaluate the carotid-femoral pulse wave velocity (PWV) values in healthy dogs using pulse wave Doppler...
-
The Circulating Levels of Selenium, Zinc, Midkine, Some Inflammatory Cytokines, and Angiogenic Factors in Mitral Chordae Tendineae Rupture
Chordae tendineae rupture process is associated with increased production of inflammatory and angiogenesis mediators in connective tissues, which...
-
Evaluation of artificial selection in Standard Poodles using whole-genome sequencing
Identifying regions of artificial selection within dog breeds may provide insights into genetic variation that underlies breed-specific traits or...
-
Trends in popularity of some morphological traits of purebred dogs in Australia
BackgroundThe morphology of dogs can provide information about their predisposition to some disorders. For example, larger breeds are predisposed to...
-
Extracellular Matrix and Cardiac Disease: Surgical and Scientific Perspectives
Scientists and surgeons can each benefit from a clear understanding of cardiac ECM and its’ influence on cardiac structure and function in both...
-
The challenges of pedigree dog health: approaches to combating inherited disease
The issue of inherited disorders and poor health in pedigree dogs has been widely discussed in recent years. With the advent of genome-wide...
-
Increased endogenous serotonin level in diabetic conditions may lead to cardiac valvulopathy via reactive oxygen species regulation
Diabetes mellitus (DM) is considered as a risk of cardiovascular diseases due to the expression of certain pathological factors, including hormones,...
-
Fibrillin-containing microfibrils are key signal relay stations for cell function
Fibrillins constitute the backbone of microfibrils in the extracellular matrix of elastic and non-elastic tissues. Mutations in fibrillins are...
-
Overview of the ADAMTS Superfamily
ADAMTS13 is an idiosyncratic member of a distinct family of zinc metalloproteases, the ADAMTS family. This 19-member family is related to ADAM...
-
Distinct Signaling Pathways Activated by “Extracellular” and “Intracellular” Serotonin in Heart Valve Development and Disease
Cardiac valve diseases are often due to developmental anomalies that progressively lead to the abnormal distribution and organization of...
-
Doppler echocardiographic evidence of pulmonary hypertension in dogs: a retrospective clinical investigation
Pulmonary hypertension (PH) decreases resistance to fatigue and life expectancy. The aim of this study was to correlate some indirect Doppler indices...
-
Targeting Wnt-Frizzled signaling in cardiovascular diseases
Wnts are secreted glycoproteins implicated in biological processes ranging from embryonic cardiac development to uncontrolled cell proliferation in...
