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Nutragenomic Approaches in Sunflower: Genetic Improvement in Oil Quality
Sunflower is an important oilseed crop. Worldwide, it ranks fifth in cultivation among oilseed crops. Sunflower oil is preferred for domestic...
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Nutragenomic Approaches in Sunflower: Genetic Improvement in Oil Quality
Sunflower is an important oilseed crop. Worldwide, it ranks fifth in cultivation among oilseed crops. Sunflower oil is preferred for domestic...
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Genetic map** of novel modifiers for ApcMin induced intestinal polyps’ development using the genetic architecture power of the collaborative cross mice
BackgroundFamilial adenomatous polyposis is an inherited genetic disease, characterized by colorectal polyps. It is caused by inactivating mutations...
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Genetic analysis of pungency deficiency in Japanese chili pepper ‘Shishito’ (Capsicum annuum) revealed its unique heredity and brought the discovery of two genetic loci involved with the reduction of pungency
The sensation of pungency generated by capsaicinoids is a characteristic trait of chili peppers ( Capsicum spp.), and the presence or absence of...
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The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil
The epigenetic modifier histone deacetylase-2 (HDAC2) is frequently dysregulated in colon cancer cells. Microsatellite instability (MSI), an...
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Epigenetic Control of Gene Expression
Genetic mutations lead to inheritable changes in the traits. Alterations in genetic features may also be caused by chromatin modifications without...
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Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene
The Nakano cataract mouse (NCT) manifests a wavy coat for their first hair as a genetic trait. In this study, we explored the molecular genetic basis...
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Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis
Synergies of transcription factors, chromatin modifiers and their target genes are vital for cell fate determination in human cancer. Although the...
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Genetic Enhancement of Nutraceuticals in Papaya (Carica papaya L.)
Not just in India, but all around the world, papaya (Carica papaya L.) is considered one of the most significant fruits. It is grown in tropical and...
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Genetic Enhancement of Nutraceuticals in Papaya (Carica papaya L.)
Not just in India, but all around the world, papaya (Carica papaya L.) is considered one of the most significant fruits. It is grown in tropical and...
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Metabolic-GWAS provides insights into genetic architecture of seed metabolome in buckwheat
BackgroundBuckwheat ( Fagopyrum spp.), belonging to the Polygonaceae family, is an ancient pseudo-cereal with high nutritional and nutraceutical...
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Genetic Evolvability: Using a Restricted Pluralism to Tidy up the Evolvability Concept
Advances in the empirical sectors of biology are beginning to reveal evolvability as a major evolutionary process. Yet evolvability’s theoretical...
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Establishment of regeneration system of Pyrus and the genetic stability analysis of regenerated population
Genetic assessment of pear regeneration population is very important for genetic fidelity maintenance in genetic engineering breeding. In this...
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Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent
Multiple Myeloma is a typical example of a neoplasm that shows significant differences in incidence, age of onset, type, and frequency of genetic...
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Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach
BackgroundThe Connemara pony (CP) is an Irish breed that has experienced varied selection by breeders over the last fifty years, with objectives...
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The applications of CRISPR/Cas-mediated genome editing in genetic hearing loss
Hearing loss (HL) can be caused by a number of different genetic factors. Non-syndromic HL refers that HL occurs as an isolated symptom in an...
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Genetic modulation of anemia severity, hemolysis level, and hospitalization rate in Angolan children with Sickle Cell Anemia
BackgroundSickle Cell Anemia (SCA) is a genetic disease caused by the c.20 A > T mutation in HBB gene, generally characterized by sickle...
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Rare genetic variants explain missing heritability in smoking
Common genetic variants explain less variation in complex phenotypes than inferred from family-based studies, and there is a debate on the source of...
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Landscape genomics reveals regions associated with adaptive phenotypic and genetic variation in Ethiopian indigenous chickens
Climate change is a threat to sustainable livestock production and livelihoods in the tropics. It has adverse impacts on feed and water availability,...
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Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
Parkinson’s disease (PD) is a debilitating neurodegenerative disease characterized by the loss of midbrain dopaminergic neurons (DaNs) and the...
