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Recent advances in RNA structurome
RNA structures are essential to support RNA functions and regulation in various biological processes. Recently, a range of novel technologies have...
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Selbstreproduktion: Zellteilung, Krebs, Stammzellen und Epigenetik
Zellkerne teilen sich im Rahmen von Mitosen, um über vielfache Zellteilungen und nachfolgende Differenzierung einen vielzelligen Körper aus...
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Ansichten zur Evolution der Zelle im Wandel der Zeit – vom Ursprung zur Vielfalt
„Am Anfang warEvolution die Erde wüst und leer“ (in der Bibel: „Tohuwabohu“), und so leer blieben lange Zeit auch die Vorstellungen, wie sich die...
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A chelicerate-specific burst of nonclassical Dscam diversity
BackgroundThe immunoglobulin (Ig) superfamily receptor Down syndrome cell adhesion molecule ( Dscam ) gene can generate tens of thousands of isoforms...
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Antioxidant responses of Fenneropenaeus chinensis to white spot syndrome virus challenge
In order to gain insights into the responsive characteristics of the antioxidant systems of shrimp during viral infection, in the present study, Fenner...
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Cell Communication-mediated Nonself-Recognition and -Intolerance in Representative Species of the Animal Kingdom
Why has histo-incompatibility arisen in evolution and can cause self-intolerance? Compatible/incompatible reactions following natural contacts...
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The p21-activated kinases in neural cytoskeletal remodeling and related neurological disorders
The serine/threonine p21-activated kinases (PAKs), as main effectors of the Rho GTPases Cdc42 and Rac, represent a group of important molecular...
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Long noncoding RNA DIAPH2-AS1 promotes neural invasion of gastric cancer via stabilizing NSUN2 to enhance the m5C modification of NTN1
Neural invasion (NI) is a vital pathological characteristic of gastric cancer (GC), which correlates with tumor recurrence and a worse prognosis....
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The role of CPEB family proteins in the nervous system function in the norm and pathology
Posttranscriptional gene regulation includes mRNA transport, localization, translation, and regulation of mRNA stability. CPEB (
c ytoplasmicp olyadenyl...
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Growth cone repulsion to Netrin-1 depends on lipid raft microdomains enriched in UNC5 receptors
During brain development, Uncoordinated locomotion 5 (UNC5) receptors control axonal extension through their sensing of the guidance molecule...
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Zelluläre Membranen. Die Zellmembran: Umschlagplatz für Stoffe und Information
In der ZellmembranZellmembran, wie in intrazellulären MembranenMembran auch, liegt nach Erkenntnissen aus dem Beginn des 20. Jahrhunderts als...
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Transcriptomics analysis of differentially expressed genes in subcutaneous and perirenal adipose tissue of sheep as affected by their pre- and early postnatal malnutrition histories
BackgroundEarly life malnutrition is known to target adipose tissue with varying impact depending on timing of the insult. This study aimed to...
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Selbstreproduktion: Zellteilung, Krebs, Stammzellen und Epigenetik
Zellkerne teilen sich Krebs im Rahmen von Mitosen, um über vielfache ZellteilungenZellteilung und nachfolgende Differenzierung einen vielzelligen...
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Integration of small RNAs, degradome, and transcriptome sequencing provides insights into the differences between Shizhu ginseng and Yuan ginseng
Panax ginseng is one of the most popular herbs which have been used as an important traditional Chinese medicine since ancient times. Yuan ginseng...
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Ansichten zur Evolution der Zelle im Wandel der Zeit – vom Ursprung zur Vielfalt
Erste Lebensformen entwickelten sich an mild temperierten weißen Rauchern ozeanischer Verwerfungen. Alles Weitere ist heute mit vergleichenden...
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Daphnia galeata responds to the exposure to an ichthyosporean gut parasite by down-regulation of immunity and lipid metabolism
BackgroundRegulatory circuits of infection in the emerging experimental model system, water flea Daphnia and their microparasites, remain largely...
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ASlive: a database for alternative splicing atlas in livestock animals
BackgroundAlternative splicing is an important biological process whose precision must be tightly regulated during growth and development. Although...
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Multi-omic profiling of primary mouse neutrophils predicts a pattern of sex- and age-related functional regulation
Neutrophils are the most abundant human white blood cell and constitute a first line of defense in the innate immune response. Neutrophils are...
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Protein kinases: master regulators of neuritogenesis and therapeutic targets for axon regeneration
Proper neurite formation is essential for appropriate neuronal morphology to develop and defects at this early foundational stage have serious...
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Structure and Function of Roundabout Receptors
The creation of complex neuronal networks relies on ligand-receptorReceptors interactions that mediate attraction or repulsion towards specific...