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Transcription bodies regulate gene expression by sequestering CDK9
The localization of transcriptional activity in specialized transcription bodies is a hallmark of gene expression in eukaryotic cells. It remains...
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The probability of chromatin to be at the nuclear lamina has no systematic effect on its transcription level in fruit flies
BackgroundMultiple studies have demonstrated a negative correlation between gene expression and positioning of genes at the nuclear envelope (NE)...
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Carbohydrates and carbohydrate degradation gene abundance and transcription in Atlantic waters of the Arctic
Carbohydrates are chemically and structurally diverse, represent a substantial fraction of marine organic matter and are key substrates for...
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Assessing Gene Expression of the Endocannabinoid System Components by Real-Time Quantitative Reverse Transcription Polymerase Chain Reaction
Real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR), a major development in PCR technology, is a powerful and sensitive...
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Nuclear Transcription Factor Detection
Cellular fate is determined by the activity of nuclear transcription factors. Here, we describe a series of protocols for detecting transcription...
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Copper increases laccase gene transcription and extracellular laccase activity in Pleurotus eryngii KS004
The white-rot fungus Pleurotus eryngii secretes various laccases involved in the degradation of a wide range of chemical compounds. Since the laccase...
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Conserved and plant-specific histone acetyltransferase complexes cooperate to regulate gene transcription and plant development
Although a conserved SAGA complex containing the histone acetyltransferase GCN5 is known to mediate histone acetylation and transcriptional...
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Regulation of ribosomal RNA gene copy number, transcription and nucleolus organization in eukaryotes
One of the first biological machineries to be created seems to have been the ribosome. Since then, organisms have dedicated great efforts to optimize...
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Gene Expression in Prokaryotes
Prokaryotes are single-celled organisms which doesn’t have nucleus. Their DNA are free floating in the cell cytoplasm. In prokaryotes, proteins are...
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NetREX-CF integrates incomplete transcription factor data with gene expression to reconstruct gene regulatory networks
The inference of Gene Regulatory Networks (GRNs) is one of the key challenges in systems biology. Leading algorithms utilize, in addition to gene...
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Regulation of Gene Expression by the MYC Transcription Factor Network During Exercise
AbstractThe results obtained in recent years on the numerous functions of the MYC protein convincingly indicate that MYC overexpression induced by...
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Enhancer Activation by Transcription Factors and Underlying Mechanisms
Enhancers are classified into two classes based on various criteria. Class I enhancersClass I enhancers participate primarily in finely tuned...
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Identification of gene-level methylation for disease prediction
DNA methylation is an epigenetic alteration that plays a fundamental part in governing gene regulatory processes. The DNA methylation mechanism...
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Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription
BackgroundHow transcription factors (TFs) down-regulate gene expression remains ill-understood, especially when they bind to multiple enhancers...
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Construction of Gene Expression Profiles of the NAC Transcription Factor Family in Sugar Beet Under Abiotic Stress
Sugar beet ( Beta vulgaris L.) is a major sugar crop in China and an economic crop with regional advantages in the Inner Mongolia Autonomous Region....
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G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes
BackgroundG-quadruplexes (G4s) are unique noncanonical nucleic acid secondary structures, which have been proposed to physically interact with...
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RNA Transcription
The process of producing proteins from nucleotides is termed as gene expression. Genetic information present in the DNA, is first rewritten,...
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NetAct: a computational platform to construct core transcription factor regulatory networks using gene activity
A major question in systems biology is how to identify the core gene regulatory circuit that governs the decision-making of a biological process....
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Lactobacilli Probiotics Modulate Antibacterial Response Gene Transcription of Dendritic Cells Challenged with LPS
Probiotics are beneficial bacteria that may modulate the immune response by altering the maturation and function of antigen-presenting cells, such as...
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Participation of the Transcription Factor CREB1 in the Regulation of the Mdh2 Gene Encoding Malate Dehydrogenase in the Liver of Rats with Alloxan-Induced Diabetes
AbstractObjective: Malate dehydrogenase (MDH, ЕC 1.1.1.37) is a multifunctional enzyme complex that catalyzes the reversible conversion of malate to...
