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Key gene modules and hub genes associated with pyrethroid and organophosphate resistance in Anopheles mosquitoes: a systems biology approach
Indoor residual spraying (IRS) and insecticide-treated nets (ITNs) are the main methods used to control mosquito populations for malaria prevention....
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Effect of dynamic exclusion and the use of FAIMS, DIA and MALDI-mass spectrometry imaging with ion mobility on amyloid protein identification
Amyloidosis is a disease characterized by local and systemic extracellular deposition of amyloid protein fibrils where its excessive accumulation in...
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A comparison of the TempO-Seq and Affymetrix microarray platform using RTqPCR validation
Next-generation risk assessment relies on mechanistic data from new approach methods, including transcriptome data. Various technologies, such as...
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Regulatory gene network for coffee-like color morph of TYRP1 mutant of oujiang color common carp
BackgroundNeither a TYRP1-mediated highly conserved genetic network underlying skin color towards optimum defense nor the pathological tendency of...
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Genome-wide association study for cashmere traits in Inner Mongolia cashmere goat population reveals new candidate genes and haplotypes
BackgroundThe cashmere goat industry is one of the main pillars of animal husbandry in Inner Mongolia Autonomous Region, and plays an irreplaceable...
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Genome-wide association study provided insights into the polled phenotype and polled intersex syndrome (PIS) in goats
BackgroundBreeding polled goats is a welfare-friendly approach for horn removal in comparison to invasive methods. To gain a comprehensive...
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Genome-wide identification and expression analysis of histone deacetylase and histone acetyltransferase genes in response to drought in poplars
BackgroundHistone deacetylases (HDACs) and histone acetyltransferases (HATs) are involved in plant growth and development as well as in response to...
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NOX4-mediated astrocyte ferroptosis in Alzheimer’s disease
This study investigates NADPH oxidase 4 (NOX4) involvement in iron-mediated astrocyte cell death in Alzheimer’s Disease (AD) using single-cell...
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Genome-wide identification and expression pattern analysis of MIKC-Type MADS-box genes in Chionanthus retusus, an androdioecy plant
BackgroundThe MADS-box gene family is widely distributed in the plant kingdom, and its members typically encoding transcription factors to regulate...
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Analysis of proteins in the light of mutations
Proteins have evolved through mutations—amino acid substitutions—since life appeared on Earth, some 10 9 years ago. The study of these phenomena has...
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Exploring selection signatures in the divergence and evolution of lipid droplet (LD) associated genes in major oilseed crops
BackgroundOil bodies or lipid droplets (LDs) in the cytosol are the subcellular storage compartments of seeds and the sites of lipid metabolism...
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Use of the Saccharomycopsis schoenii MET17 promoter for regulated heterologous gene expression
The ability to regulate the expression of genes is a central tool for the characterization of fungal genes. This is of particular interest to study...
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Identification and expression analysis of Sox family genes in echinoderms
The Sox gene family, a collection of transcription factors widely distributed throughout the animal kingdom, plays a crucial role in numerous...
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Breed of origin analysis in genome-wide association studies: enhancing SNP-based insights into production traits in a commercial Brangus population
BackgroundCarcass weight (HCW) and marbling (MARB) are critical for meat quality and market value in beef cattle. In composite breeds like Brangus,...
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Taking another look at intelligence and personality using an eye-tracking approach
Intelligence and personality are both key drivers of learning. This study extends prior research on intelligence and personality by adopting a...
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Resistin as a potential diagnostic biomarker for sepsis: insights from DIA and ELISA analyses
PurposeThe primary objective of this investigation is to systematically screen and identify differentially expressed proteins (DEPs) within the...
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Integrated transcriptome and microRNA analysis reveals molecular responses to high-temperature stress in the liver of American shad (Alosa sapidissima)
BackgroundFish reproduction, development and growth are directly affected by temperature, investigating the regulatory mechanisms behind high...
