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Targeting specific DNA G-quadruplexes with CRISPR-guided G-quadruplex-binding proteins and ligands
Despite the demonstrated importance of DNA G-quadruplexes (G4s) in health and disease, technologies to readily manipulate specific G4 folding for...
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Pheretimoid earthworms of India: new insight from molecular systematics and phylogenetic relationship with new records
Around the world, the spread of pheretimoid earthworm species from Southeast Asia has raised ecological, environmental, and conservation concerns in...
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Characterization and arbovirus susceptibility of cultured CERNI cells derived from sika deer (Cervus nippon)
Cervus nippon (sika deer) are widely distributed throughout eastern Asia. Deer possess a variety of antibodies against several zoonotic pathogens,...
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Mechanistic insights into the basis of widespread RNA localization
The importance of subcellular mRNA localization is well established, but the underlying mechanisms mostly remain an enigma. Early studies suggested...
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Phylogeography and evolutionary history of the burrowing scorpion genus Scorpio Linnaeus, 1758 (Scorpiones: Scorpionidae) in the Mediterranean Basin
The burrowing scorpions of the genus Scorpio Linnaeus, 1758 were considered to be a single polymorphic species, Scorpio maurus Linnaeus, 1758,...
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Carryover effects of salinity impact propagule release by a common marine biofouling species
The spread of marine non-indigenous species (NIS) is driven largely by ship** and global trade. Biofouling on vessel hulls is a major source of...
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Plasma metabolomic and lipidomic profiles accurately classify mothers of children with congenital heart disease: an observational study
IntroductionCongenital heart disease (CHD) is the most common congenital anomaly, representing a significant global disease burden. Limitations exist...
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Inoculation with native bacterial endophytes promote adventitious rooting and plant growth in Piper longum L.
Piper longum , the Indian long pepper, is widely used in Ayurvedic medicine system to cure respiratory and digestive disorders. In a previous study,...
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Implicating clinical utility of altered expression of PTCH1 & SMO in oral squamous cell carcinoma
IntroductionOral cancer poses a significant burden on public health in India, with higher incidence and mortality rates. Despite advancements in...
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VAMP2 regulates phase separation of α-synuclein
α-Synuclein (αSYN), a pivotal synaptic protein implicated in synucleinopathies such as Parkinson’s disease and Lewy body dementia, undergoes protein...
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Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration
Ras has been extensively studied as a promoter of cell proliferation, whereas few studies have explored its role in migration. To investigate the...
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Inhibitory immune checkpoints suppress the surveillance of senescent cells promoting their accumulation with aging and in age-related diseases
The accumulation of pro-inflammatory senescent cells within tissues is a common hallmark of the aging process and many age-related diseases. This...
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Ecological niche modeling for the prediction of suitable environments for Chrysodeixis chalcites (Noctuidae) in the contiguous United States
The golden twin-spot moth, Chrysodeixis chalcites Esper (Lepidoptera: Noctuidae), is a polyphagous, polyvoltine crop pest occurring natively from...
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VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates
α-Synuclein (α-Syn) aggregation is closely associated with Parkinson’s disease neuropathology. Physiologically, α-Syn promotes synaptic vesicle (SV)...
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Density, biomass, and fruit and seed production potential of Mexican prickly poppy (Argemone mexicana L.) invasive alien plant species under different land uses and agroecology in South Wollo, Ethiopia
An increase in the establishment and spread of invasive alien plant species (IAPS) poses significant socioeconomic and environmental impacts. This...
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Solidago gigantea invasion homogenizes soil properties and native plant communities
Solidago gigantea , a notorious invasive species in Europe and Asia, has been shown in previous studies to impact soil properties such as nutrient...
