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Systematic assessment of long-read RNA-seq methods for transcript identification and quantification
The Long-read RNA-Seq Genome Annotation Assessment Project Consortium was formed to evaluate the effectiveness of long-read approaches for...
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Skeletal microstructures of cheilostome bryozoans (phylum Bryozoa, class Gymnolaemata): crystallography and secretion patterns
Gymnolaemata bryozoans produce CaCO 3 skeletons of either calcite, aragonite, or both. Despite extensive research, their crystallography and...
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Examination of wnt signaling mediated melanin transport and shell color formation in Pacific oyster (Crassostrea gigas)
Mollusca exhibit remarkable diversity in shell coloration, attributed to the presence of melanin, a widely distributed pigment with various essential...
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Chromatin remodelers: a concise introduction for biophysicists
Chromatin remodelers are molecular motors that act on nucleosomes: they move them along DNA or (dis-)assemble them. Despite the fact that they...
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Scanorama: integrating large and diverse single-cell transcriptomic datasets
Merging diverse single-cell RNA sequencing (scRNA-seq) data from numerous experiments, laboratories and technologies can uncover important biological...
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Revisiting superiority and stability metrics of cultivar performances using genomic data: derivations of new estimators
The selection of highly productive genotypes with stable performance across environments is a major challenge of plant breeding programs due to...
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Large-scale foundation model on single-cell transcriptomics
Large pretrained models have become foundation models leading to breakthroughs in natural language processing and related fields. Develo**...
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Molecular recording using DNA Typewriter
Recording molecular information to genomic DNA is a powerful means of investigating topics ranging from multicellular development to cancer...
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Accurate and efficient integrative reference-informed spatial domain detection for spatial transcriptomics
Spatially resolved transcriptomics (SRT) studies are becoming increasingly common and large, offering unprecedented opportunities in map** complex...
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Deconwolf enables high-performance deconvolution of widefield fluorescence microscopy images
Microscopy-based spatially resolved omic methods are transforming the life sciences. However, these methods rely on high numerical aperture...
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Large-scale deep tissue voltage imaging with targeted-illumination confocal microscopy
Voltage imaging with cellular specificity has been made possible by advances in genetically encoded voltage indicators. However, the kilohertz rates...
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Impacts of climate change on mangrove subsistence fisheries: a global review
Climate change will impact coastal ecosystems, threatening subsistence fisheries including those in mangrove forests. Despite their global...
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All-optical voltage imaging-guided postsynaptic single-cell transcriptome profiling with Voltage-Seq
Neuronal pathways recruit large postsynaptic populations and maintain connections via distinct postsynaptic response types (PRTs). Until recently,...
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Effects and avoidance of photoconversion-induced artifacts in confocal and STED microscopy
Fluorescence microscopy is limited by photoconversion due to continuous illumination, which results in not only photobleaching but also conversion of...
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Real-time imaging of axonal membrane protein life cycles
The construction of neuronal membranes is a dynamic process involving the biogenesis, vesicular packaging, transport, insertion and recycling of...
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Universal inverse modeling of point spread functions for SMLM localization and microscope characterization
The point spread function (PSF) of a microscope describes the image of a point emitter. Knowing the accurate PSF model is essential for various...
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