Search
Search Results
-
Trimetaphosphate Activates Prebiotic Peptide Synthesis across a Wide Range of Temperature and pH
The biochemical activation of amino acids by adenosine triphosphate (ATP) drives the synthesis of proteins that are essential for all life. On the...
-
Correction to: Publication of Abstracts and Full Papers from the International Conference on the Origin of Life, San Diego, 2017
Plans for the publication of Abstracts from the meeting have been cancelled. However, manuscripts for full papers will still be considered for...
-
Models of Replicator Proliferation Involving Differential Replicator Subunit Stability
Several models for the origin of life involve molecules that are capable of self-replication, such as self-replicating polymers composed of RNA or...
-
Investigating the Kinetics of Montmorillonite Clay-Catalyzed Conversion of Anthracene to 9,10-Anthraquinone in the Context of Prebiotic Chemistry
Carbonaceous meteorites contributed polycyclic aromatic hydrocarbons (PAHs) to the organic inventory of the primordial Earth where they may have...
-
Water near its Supercritical Point and at Alkaline pH for the Production of Ferric Oxides and Silicates in Anoxic Conditions. A New Hypothesis for the Synthesis of Minerals Observed in Banded Iron Formations and for the Related Geobiotropic Chemistry inside Fluid Inclusions
An alternative hypothesis for the origin of the banded iron formations and the synthesis of prebiotic molecules is presented here. I show the...
-
The Standard Genetic Code can Evolve from a Two-Letter GC Code Without Information Loss or Costly Reassignments
It is widely agreed that the standard genetic code must have been preceded by a simpler code that encoded fewer amino acids. How this simpler code...
-
Synthesis of β-Peptide Standards for Use in Model Prebiotic Reactions
A one-pot method was developed for the preparation of a series of β-alanine standards of moderate size (2 to ≥12 residues) for studies concerning the...
-
In the Beginning was a Mutualism - On the Origin of Translation
The origin of translation is critical for understanding the evolution of life, including the origins of life. The canonical genetic code is one of...
-
Selective Formation of Ser-His Dipeptide via Phosphorus Activation
The Ser-His dipeptide is the shortest active peptide. This dipeptide not only hydrolyzes proteins and DNA but also catalyzes the formation of...
-
Acetyl Phosphate as a Primordial Energy Currency at the Origin of Life
Metabolism is primed through the formation of thioesters via acetyl CoA and the phosphorylation of substrates by ATP. Prebiotic equivalents such as...
-
Salinity Effects on the Adsorption of Nucleic Acid Compounds on Na-Montmorillonite: a Prebiotic Chemistry Experiment
Any proposed model of Earth’s primitive environments requires a combination of geochemical variables. Many experiments are prepared in aqueous...
-
A Proposal of the Ur-proteome
Herein we outline a plausible proteome, encoded by assuming a primeval RNY genetic code. We unveil the primeval phenotype by using only the RNA...
-
Chiral Symmetry Breaking in Peptide Systems During Formation of Life on Earth
Chiral symmetry breaking in complex chemical systems with a large number of amino acids and a large number of similar reactions was considered. It...
-
Phenotypic Graphs and Evolution Unfold the Standard Genetic Code as the Optimal
In this work, we explicitly consider the evolution of the Standard Genetic Code (SGC) by assuming two evolutionary stages, to wit, the primeval RNY...
-
Primary Formation Path of Formaldehyde in Hydrothermal Vents
Formaldehyde is abundant in the universe and one of the fundamental molecules for life. Hydrothermal vents produce a substantial amount of hydrogen...
-
Amorphous Silica-Promoted Lysine Dimerization: a Thermodynamic Prediction
It has long been suggested that mineral surfaces played a crucial role in the abiotic polymerization of amino acids that preceded the origin of life....
