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1. 6 Sterol biochemistry and regulation in the yeast Saccharomyces cerevisiae

   Saccharomyces cerevisiae has been a major model system for the study of sterol biosynthesis and function. All of the genes encoding the enzymes...

   N. Douglas Lees, Martin Bard in Lipid Metabolism and Membrane Biogenesis

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2. 7 Mammalian ACAT and DGAT2 gene families

   Mammalian isozymes of ACAT, DGAT, and MGAT are encoded by the ACAT and DGAT2 gene families. These enzymes catalyze the synthesis of neutral lipid...

   Dong Cheng, Jay Liu, ... Ta-Yuan Chang in Lipid Metabolism and Membrane Biogenesis

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3. Conserved ribosomal RNA modification and their putative roles in ribosome biogenesis and translation

   rRNA maturation requires extensive covalent modifications of riboses and bases. These modifications concern exclusively the most conserved regions of...

   Bruno Lapeyre in Fine-Tuning of RNA Functions by Modification and Editing

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4. Biosynthesis and function of tRNA wobble modifications

   Post-transcriptional modifications at the first (wobble) position of the tRNA anticodon participate in the precise decoding of the genetic code that...

   Tsutomu Suzuki in Fine-Tuning of RNA Functions by Modification and Editing

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5. From isolation to integration, a systems biology approach for building the Silicon Cell

   In the last decade, the field now commonly referred to as systems biology has developed rapidly. With the sequencing of whole genomes and the...

   Jacky L. Snoep, Hans V. Westerhoff in Systems Biology

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6. Genome evolution: Lessons from Genolevures

   In the past years, yeast genome-sequencing programs have been widely developed. Two of them, namely Genolevures I and II, were devoted to the...

   Monique Bolotin-Fukuhara, Serge Casaregola, Michel Aigle in Comparative Genomics

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7. Histone Ubiquitylation and the Regulation of Transcription

   The small (76 amino acids) and highly conserved ubiquitin protein plays key roles in the physiology of eukaryotic cells. Protein ubiquitylation...

   Mary Ann Osley, Alastair B. Fleming, Cheng-Fu Kao in Chromatin Dynamics in Cellular Function

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8. The Generation and Recognition of Histone Methylation

   The posttranslational modification of histone proteins via methylation has important functions in gene activation, transcriptional silencing,...

   Michael S. Torok, Patrick A. Grant in Chromatin Dynamics in Cellular Function

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9. Histone Dynamics During Transcription: Exchange of H2A/H2B Dimers and H3/H4 Tetramers During Pol II Elongation

   Chromatin within eukaryotic cell nuclei accommodates many complex activities that require at least partial disassembly and reassembly of...

   Christophe Thiriet, Jeffrey J. Hayes in Chromatin Dynamics in Cellular Function

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10. Folding of newly synthesised proteins in the endoplasmic reticulum

    The endoplasmic reticulum (ER) is a membranous compartment that can be found within any nucleated eukaryotic cell. Its job is to oversee the...

    Sanjika Dias-Gunasekara, Adam M. Benham in Chaperones

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11. Mouse Models of Cell Cycle Regulators: New Paradigms

    In yeast, a single cyclin-dependent kinase (Cdk) is able to regulate diverse cell cycle transitions (S and M phases) by associating with multiple...

    Eiman Aleem, Philipp Kaldis in Cell Cycle Regulation

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12. Structural features of fungal genomes

    Eighteen fungal genomes have been sequenced to date from a variety of taxonomic groups, with fifteen Ascomycota, two Basidomycota and one...

    Phatthanaphong Wanchanthuek, Peter F. Hallin, ... David Ussery in Comparative Genomics

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13. Sterol Endocytosis and Trafficking in Plant Cells

    Structural sterols are integral components of biological membranes. They regulate membrane permeability and fluidity, and they influence the...

    Miroslav Ovečka, Irene K. Lichtscheidl in Plant Endocytosis

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14. SNAREs in Plant Endocytosis and the Post-Golgi Traffic

    In eukaryotic cells, the transport vesicles carry various cargo proteins from a donor compartment to a target compartment, and discharge the cargo...

    Masa H. Sato, Ryosuke L. Ohniwa, Tomohiro Uemura in Plant Endocytosis

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15. Plant Vacuoles: from Biogenesis to Function

    The plant vacuolar system is far more complex than originally expected and multiple sorting pathways leading to various types of vacuoles can be...

    Jean-Marc Neuhaus, Nadine Paris in Plant Endocytosis

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16. Endocytosis in Guard Cells

    Stomatal movement requires large and repetitive changes to cell volume and consequently surface area. These alterations in surface area are...

    Ulrike Homann in Plant Endocytosis

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17. Endocytosis and Actomyosin Cytoskeleton

    Mutual interactions between actin and endocytic assembly machineries are essential for successful clathrin-mediated endocytosis in yeast and...

    Jozef Šamaj, František Baluška, ... Diedrik Menzel in Plant Endocytosis

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18. Endocytosis and Membrane Recycling in Pollen Tubes

    In plants, tip-growing cells are an ideal system to investigate signal transduction mechanisms and, among these, pollen tubes are one of the...

    Rui Malhó, Pedro Castanho Coelho, ... Jan Derksen in Plant Endocytosis

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19. Plant Prevacuolar Compartments and Endocytosis

    Prevacuolar compartments (PVCs) are membrane-bound organelles mediating protein traffic from both Golgi and plasma membrane to vacuoles in...

    Sheung Kwan Lam, Yu Chung Tse, ... David G. Robinson in Plant Endocytosis

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20. The Roles of Chromatin Remodelling Factors in Replication

    Dynamic changes of chromatin structure control DNA-dependent events, including DNA replication. Along with DNA, chromatin organization must be...

    Ana Neves-Costa, Patrick Varga-Weisz in Chromatin Dynamics in Cellular Function

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