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A comprehensive review of computational cell cycle models in guiding cancer treatment strategies
This article reviews the current knowledge and recent advancements in computational modeling of the cell cycle. It offers a comparative analysis of...
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Deepvirusclassifier: a deep learning tool for classifying SARS-CoV-2 based on viral subtypes within the coronaviridae family
PurposeIn this study, we present DeepVirusClassifier, a tool capable of accurately classifying Severe Acute Respiratory Syndrome Coronavirus 2...
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Identification and characterization of the RcTCP gene family and its expression in response to abiotic stresses in castor bean
BackgroundThe TCP ( teosinte branched1/cincinnata/proliferating cell factor ) family plays a prominent role in plant development and stress responses....
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Genetic diversity and population structure of wheat landraces in Southern Winter Wheat Region of China
BackgroundWheat landraces are considered a valuable source of genetic diversity for breeding programs. It is useful to evaluate the genetic diversity...
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Genome-wide identification and molecular evolution of Dof transcription factors in Cyperus esculentus
Dof transcription factor family in Cyperus esculentus genome was identified and analyzed using bioinformatics. The analysis results revealed that C.esculentus...
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Metabolomic and transcriptomic analyses of peach leaves and fruits in response to pruning
BackgroundPruning is an important cultivation management option that has important effects on peach yield and quality. However, the effects of...
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Development of pre-implantation genetic testing protocol for monogenic disorders (PGT-M) of Hb H disease
Hb H disease is the most severe form of α-thalassemia compatible with post-natal life. Compound heterozygous α 0 -thalassemia − SEA deletion/α + -thalassemia...
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Systematic characterization of immunoglobulin loci and deep sequencing of the expressed repertoire in the Atlantic cod (Gadus morhua)
BackgroundThe Atlantic cod is a prolific species in the Atlantic, despite its inconsistent specific antibody response. It presents a peculiar case...
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Key gene modules and hub genes associated with pyrethroid and organophosphate resistance in Anopheles mosquitoes: a systems biology approach
Indoor residual spraying (IRS) and insecticide-treated nets (ITNs) are the main methods used to control mosquito populations for malaria prevention....
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A comparison of the TempO-Seq and Affymetrix microarray platform using RTqPCR validation
Next-generation risk assessment relies on mechanistic data from new approach methods, including transcriptome data. Various technologies, such as...
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Filter bank temporally local multivariate synchronization index for SSVEP-based BCI
BackgroundMultivariate synchronization index (MSI) has been successfully applied for frequency detection in steady state visual evoked potential...
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Regulatory gene network for coffee-like color morph of TYRP1 mutant of oujiang color common carp
BackgroundNeither a TYRP1-mediated highly conserved genetic network underlying skin color towards optimum defense nor the pathological tendency of...
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Genome-wide association study for cashmere traits in Inner Mongolia cashmere goat population reveals new candidate genes and haplotypes
BackgroundThe cashmere goat industry is one of the main pillars of animal husbandry in Inner Mongolia Autonomous Region, and plays an irreplaceable...
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Genome-wide association study provided insights into the polled phenotype and polled intersex syndrome (PIS) in goats
BackgroundBreeding polled goats is a welfare-friendly approach for horn removal in comparison to invasive methods. To gain a comprehensive...
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Unraveling Brain Synchronisation Dynamics by Explainable Neural Networks using EEG Signals: Application to Dyslexia Diagnosis
AbstractThe electrical activity of the neural processes involved in cognitive functions is captured in EEG signals, allowing the exploration of the...
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Genome-wide identification and expression analysis of histone deacetylase and histone acetyltransferase genes in response to drought in poplars
BackgroundHistone deacetylases (HDACs) and histone acetyltransferases (HATs) are involved in plant growth and development as well as in response to...
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SGCP: a spectral self-learning method for clustering genes in co-expression networks
BackgroundA widely used approach for extracting information from gene expression data employs the construction of a gene co-expression network and...
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Unsupervised modeling of mutational landscapes of adeno-associated viruses viability
Adeno-associated viruses 2 (AAV2) are minute viruses renowned for their capacity to infect human cells and akin organisms. They have recently emerged...
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Hitac: a hierarchical taxonomic classifier for fungal ITS sequences compatible with QIIME2
BackgroundFungi play a key role in several important ecological functions, ranging from organic matter decomposition to symbiotic associations with...