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Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
The global COVID-19 pandemic caused by SARS-CoV2 infected millions of people and resulted in more than 4 million deaths worldwide. Apart from...
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Advanced tools and methods for single-cell surgery
Highly precise micromanipulation tools that can manipulate and interrogate cell organelles and components must be developed to support the rapid...
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Bioinspired nanotopographical design of drug delivery systems
Effective drug delivery is important in the treatment of various biomedical conditions, ranging from autoimmune disorders to cancer and bacterial...
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The emerging role of nanotechnology in plant genetic engineering
Genetic engineering to improve the capabilities of plants is essential given climate change and population growth pressures. Current manipulation...
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Enhancing chemical and physical stability of pharmaceuticals using freeze-thaw method: challenges and opportunities for process optimization through quality by design approach
The freeze-thaw (F/T) method is commonly employed during the processing and handling of drug substances to enhance their chemical and physical...
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Nanotechnology for Personalized Medicine
Personalized medicine, also known as precision medicine, redefines current clinical practice by altering treatments to account for patient... -
Nanotechnology for Personalized Medicine
Personalized medicine, also known as precision medicine, redefines current clinical practice by altering treatments to account for patient... -
Subcutaneous drug delivery from nanoscale systems
Various types of nanoscale drug delivery systems (DDSs) have been developed for therapeutic and/or diagnostic applications. However, most systems...
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Harnessing Synthetic Strategies for Enhanced Gold Nanoparticle Functionality in Cancer Treatment
Customized nanoparticles are being used to treat cancer, improve patient outcomes, and reduce mortality. Due to their unique and multifaceted...
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Emerging Biomimetic Approaches in the Optimization of Drug Therapies
Pharmacology is the study of drug action and applications in living organisms. A significant aspect of pharmacology is the use of natural,... -
A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions
The ability of endothelial cells to respond to blood flow is fundamental for the correct formation and maintenance of a functional and hierarchically...
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Microfluidic-based technologies for diagnosis, prevention, and treatment of COVID-19: recent advances and future directions
The COVID-19 pandemic has posed significant challenges to existing healthcare systems around the world. The urgent need for the development of...
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Engineering photodynamics for treatment, priming and imaging
Photodynamic therapy (PDT) is a photochemistry-based treatment approach that relies on the activation of photosensitizers by light to locally...
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Bio-Nanocarriers for Lung Cancer Management: Befriending the Barriers
Lung cancer is a complex thoracic malignancy develo** consequential to aberrations in a myriad of molecular and biomolecular signaling pathways. It...
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Nanotechnology for Manipulating Cell Plasticity
With the recent advances in nanomedicine, nanotechnology has developed a niche for itself as a promising option to improve healthcare via its unique... -
Applications of Advanced Nanomaterials in Biomedicine, Pharmaceuticals, Agriculture, and Food Industry
Nanotechnology has currently grown rapidly in various areas. Limiting particle size to the nanometer-scale changes the physical, optical, chemical,...
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Non-viral gene delivery to human mesenchymal stem cells: a practical guide towards cell engineering
In recent decades, human mesenchymal stem cells (hMSCs) have gained momentum in the field of cell therapy for treating cartilage and bone injuries....
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Nano-bio Interactions in the Lung
Understanding interactions between nanoparticles (NPs) and living organisms is of crucial importance for advancing biomedical applications such as... -
Unleashing the Potential of Ibrutinib-Loaded Nanoparticles for Cancer Treatment—A Comprehensive Review
This review provides a comprehensive examination of ibrutinib (Ibr), highlighting its wide-ranging utilization in the treatment of diverse...
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Micelle-like nanoparticles as siRNA and miRNA carriers for cancer therapy
Gene therapy has emerged as an alternative in the treatment of cancer, particularly in cases of resistance to chemo and radiotherapy. Different...