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Single-Cell Proteomics
Single-cell proteomics refers to the analysis and characterization of proteins expressed in individual cells. The purpose of studying single-cell... -
Algorithmic Challenges in Structural Molecular Biology and Proteomics
This paper reviews our research in computational biology and chemistry. Some of the most challenging and influential opportunities for Physical... -
Proteomics Protocols for Characterization of Xeno-immunogens in Decellularized Organs
Recently, the decellularized organs and their usage as biological scaffolds have been demonstrated as a promising tool for clinical transplantation.... -
Proteomics Identifies Calcineurin as a Potential Target for Cardiovascular Disorders in Rats Exposed to Simulated Microgravity
Microgravity can cause abnormalities and even damage to the cardiovascular system. We investigated if differences exist in the expression level of...
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A Mediator Approach for a Semantic Integration of Heterogeneous Proteomics Data Sources
With the advance of high-throughput technologies, biological data sources are growing at an exponential rate. Data integration systems that combine... -
An Accelerated Computational Approach in Proteomics
The advent of new technologies and research in the field of computational bioinformatics has revolutionized the rate of biological data generation.... -
Supervised Techniques in Proteomics
Proteomics, a field of bioinformatics majorly deals with the study of proteins and its structures in a predefined set of conditions. Integration of... -
Accelerated Deep Learning in Proteomics—A Review
Advent of deep learning in 2012 has revolutionized the plethora of researches including bioinformatics. This revolution is complemented by the... -
Emerging Trends in Big Data Analysis in Computational Biology and Bioinformatics in Health Informatics: A Case Study on Epilepsy and Seizures
Advanced technology innovations allow cost-effective, high-throughput profiling of biological systems. It enabled genome sequencing in days using... -
Role of omics approaches in vegetable breeding for insect pest resistance
Vegetables are usually herbaceous and succulent plants. This succulent nature of vegetable crops makes them susceptible to attack by a wide variety...
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Nanotechnology for Personalized Medicine
Personalized medicine, also known as precision medicine, redefines current clinical practice by altering treatments to account for patient... -
A Conundrum Waiting for Clinical, Technical, and Medico-Legal Solutions: Looking for the “Perfect Biomarker” of Perinatal Asphyxia
This chapter addresses the more recent discovery of “-omic” putative biomarkers of perinatal asphyxia. The urgent need for more tools to intercept as... -
Single-Cell Proteomics
Single-cell proteomics refers to the analysis and characterization of proteins expressed in individual cells. The purpose of studying single-cell... -
Primary Human Cell-Derived Extracellular Matrix from Decellularized Fibroblast Microtissues with Tissue-Dependent Composition and Microstructure
PurposeHuman extracellular matrix (ECM) exhibits complex protein composition and architecture depending on tissue and disease state, which remains...
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Non-canonical amino acid labeling in proteomics and biotechnology
Metabolic labeling of proteins with non-canonical amino acids (ncAAs) provides unique bioorthogonal chemical groups during de novo synthesis by...
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A Review on Machine Learning Aided Multi-omics Data Integration Techniques for Healthcare
To understand the mechanism of biological processes inside a human, it is necessary to look at its various regulatory aspects, such as DNA... -
Novel and Conventional Uses of Fungi in Products and Services
Conventionally, fungi have been featured heavily in the production of food and beverages, biofertilizers, biopesticides, industrial enzymes, and... -
Nanotechnology for Personalized Medicine
Personalized medicine, also known as precision medicine, redefines current clinical practice by altering treatments to account for patient... -
Engineering of Trophoblast Extracellular Vesicle-Delivering Hydrogels for Localized Tolerance Induction in Cell Transplantation
PurposeThe need for chronic systemic immunosuppression, which presents a host of acute risks to transplantation patients, remains the primary...
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A Systematic Review on Biomarker Identification for Cancer Diagnosis and Prognosis in Multi-omics: From Computational Needs to Machine Learning and Deep Learning
Biomarkers, also known as biological markers, are substances like transcripts, deoxyribonucleic acid (DNA), genes, proteins, and metabolites that...