Search
Search Results
-
Porphyrin-derived carbon dots for an enhanced antiviral activity targeting the CTD of SARS-CoV-2 nucleocapsid
BackgroundSince effective antiviral drugs for COVID-19 are still limited in number, the exploration of compounds that have antiviral activity against...
-
In silico multi-epitope Bunyumwera virus vaccine to target virus nucleocapsid N protein
BackgroundBunyumwera virus can cause 82% mortality in humans currently with no vaccine or drugs for treatment. We described an in silico...
-
A Comparison of Single-Sized and Mixed-Sized Particles on Lateral Flow Assay Performance for SARS-CoV-2 Nucleocapsid Protein Detection
There are several factors that can affect the sensitivity and reproducibility of the lateral flow assay, such as the size of gold nanoparticles...
-
Analysing the impact of the two most common SARS-CoV-2 nucleocapsid protein variants on interactions with membrane protein in silico
As the body of scientific research focusing on the severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 continues to grow, several mutations...
-
Spike- and nucleocapsid-based gold colloid assay toward the development of an adhesive bandage for rapid SARS-CoV-2 immune response detection and screening
Immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies are important biomarkers used for the diagnosis and screening of severe acute...
-
Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2
The global COVID-19 pandemic caused by SARS-CoV2 infected millions of people and resulted in more than 4 million deaths worldwide. Apart from...
-
A multi-population-based genomic analysis uncovers unique haplotype variants and crucial mutant genes in SARS-CoV-2
BackgroundCOVID-19 is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Rigorous detection and treatment strategies...
-
Analysis of the SARS-COV-2 Molecular Sequences Using Bioinformatics Tools
The aim of the study was to analyze the amino acid sequences of the SARS-CoV-2 coronavirus and homologous sequences with the use of bioinformatics...
-
A Data Analytics-Based Study in SARS-CoV-2 Genome Revealed a Commonality in the Infection Pattern
Severe acute respiratory syndrome (SARS) is an infection caused by the virus SARS-CoV-2, initially reported in the Wuhan province of China. Due to...
-
SARS-CoV-2 Structural Proteins Exposure Alter Thrombotic and Inflammatory Responses in Human Endothelial Cells
IntroductionWe have experienced a pandemic induced by the interaction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) structural...
-
Pandemic Effect of COVID-19: Identification, Present Scenario, and Preventive Measures Using Machine Learning Model
Mutation in viruses is known to be an unavoidable phenomenon. But at times, it may become a life-threatening pandemic just like in the case of the...
-
Analysis of COVID-19 Genome Using Continuous Wavelet Transform
The virus has been a debatable topic for decades as it cannot be placed anywhere in the classification, as viruses are neither dead nor alive. These...
-
Engineering synthetic biomolecular condensates
The concept of phase-separation-mediated formation of biomolecular condensates provides a new framework to understand cellular organization and...
-
C-MEMS-derived glassy carbon electrochemical biosensors for rapid detection of SARS-CoV-2 spike protein
According to a World Health Organization (WHO) report, the world has experienced more than 766 million cases of positive SARS-CoV-2 infection and...
-
Computational Intelligence in Identification of Some FDA Approved Drug Compounds for Treatment of COVID-19
Due to unavailability of FDA approved drug for COVID-19, pursuing of available drugs are highlighted to stop COVID-19. Insilico investigation by...
-
En route to Peptide Therapeutics for COVID 19: Harnessing Potential Antigenic Mimicry Between Viral and Human Proteins
Molecular mimicry is a general strategy used by pathogens to infect the host cells. The emergence of SARS-CoV-2 virus has resulted in more than...
-
SARS-CoV-2: Potential Drug Targets and Its Virtual Screening
The well-established structure of SARS-CoV-2 proteins has opened the door for the drug development of the potent inhibitors. The interaction of spike...
-
Covid-19 Monitoring Using Wastewater-Based Epidemiology: The Promise and Peril of Seeking Useable Data in a Pandemic
We evaluated sampling design in wastewater-based epidemiology to monitor SARS-CoV-2 RNA signal, with a focus on sampling site selection. Sampling in...
-
Automatic GO Annotation of Gene Products in SARS-CoV-2
The main goal of SARS-Cov2 gene product annotation is to identify the protein’s role in biological processes and disease-leading genes. Protein...
-
Modelling the Effect of Geometry and Loading on Mechanical Response of SARS-CoV-2
In recent times, coronavirus (SARS-CoV-2) becomes a pandemic disease across the globe. This virus affects the severe acute respiratory system that...
