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Kidney Disease and Its Replacement Techniques Utilizing MEMS-Microfluidics Technology: A Systematic Review
The human body is complex but very interesting to discover. The human body has many unsolved riddles which yet haven’t been answered and sometimes...
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Spheroids, organoids and kidneys-on-chips: how complex human cellular models have assisted in the study of kidney disease and renal ciliopathies
Kidney disease is one of the leading causes of morbidity worldwide, emphasizing the importance for physiologically accurate disease models. With most...
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Organs-on-a-Chip: Principles and Applications
Organs-on-a-Chip (OOC) corresponds to an innovative technology that mimics the complex systemic interactions of the human body, with different cells...
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Integrating organoids and organ-on-a-chip devices
Organoids and organs-on-chips are two rapidly emerging 3D cell culture techniques that aim to bridge the gap between in vitro 2D cultures and animal...
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Organ-on-a-Chip
Starting from this chapter, we will cover the practical applications of tissue engineering. The first example is organ-on-a-chip (OOC). OOC mimics...
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Advanced Topics
We have now arrived at the final chapter. We have covered all fundamental theories and laboratory techniques necessary for tissue engineering...
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Mimicking Human Kidney: Research Towards Better Solutions for Kidney Failure
The human body is a highly sophisticated machine that is not fully understood to date. The body function is highly dependent on the versatile...
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Geometry modifications of single-lip drills to improve cutting fluid flow
For single-lip drills with small diameters, the cutting fluid is supplied through a kidney-shaped cooling channel inside the tool. In addition to...
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Potential Applications of Microfluidics to Acute Kidney Injury Associated with Viral Infection
The kidneys are susceptible to adverse effects from many diseases, including several that are not tissue-specific. Acute kidney injury is a common...
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Real-time sensors for live monitoring of disease and drug analysis in microfluidic model of proximal tubule
The quest to replace animal models used in drug testing owing to their lack of accuracy in reflecting human physiology, and the higher comparative...
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Bioinspired Nanomaterials and Nanostructures from Nanobiology to Nanomedicine
Bioinspired nanomaterials and nanostructures have received much attention in the field of biology and medicine. This chapter summarizes the progress...
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Construction of in vitro liver-on-a-chip models and application progress
The liver is the largest internal organ of the human body. It has a complex structure and function and plays a vital role in drug metabolism. In...
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On-chip construction of a fully structured scaffold-free vascularized renal tubule
Renal tubule chips have emerged as a promising platform for drug nephrotoxicity testing. However, the reported renal tubule chips hardly replicate...
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Recent Advances in Plasmonic Biosensors for Digital Healthcare Applications
The field of biosensing technology has witnessed remarkable advancements in recent years, particularly with the emergence of plasmonic biosensors....
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Biomedical Microelectromechanical System for Molecular, Cellular, and Organ Study
In decades, Microelectromechanical System (MEMS)-based devices have opened up new frontiers of research in biomedical engineering that benefit from...
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Mimicking kidney re-absorption using microfluidics by considering hydrostatic pressure inside kidney tubules: structural and analytical study
Kidney failure is a common disease prevailing in the present generation. Renal disfunction inflict adverse effects on human health that are much...
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Polymeric and biological membranes for organ-on-a-chip devices
Membranes are fundamental elements within organ-on-a-chip (OOC) platforms, as they provide adherent cells with support, allow nutrients (and other...
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Microdevice for Plasma Separation and in Vitro Quantification of Plasma Proteins
Recent advances in engineering have demonstrated the use of microfluidic devices as a platform for bioanalytical applications. Over the last few...
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Bioinspired Nanomaterials and Nanostructures from Nanobiology to Nanomedicine
Bioinspired nanomaterials and nanostructures have received much attention in the field of biology and medicine. This chapter summarizes the progress...
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Artificial urinary biomarker probes for diagnosis
Urinalysis is a widely used medical test for healthcare monitoring and disease diagnosis. However, traditional urinalysis relies on endogenous...
