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Flow simulation-based particle swarm optimization for develo** improved hemolysis models
The improvement and development of blood-contacting devices, such as mechanical circulatory support systems, is a life saving endeavor. These devices...
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Examining the universality of the hemolysis power law model from simulations of the FDA nozzle using calibrated model coefficients
Computational fluid dynamics (CFD) is widely used to predict mechanical hemolysis in medical devices. The most popular hemolysis model is the...
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Qualitative Hemolysis Analyses in VAD by Stress Distribution Using Computational Hemodynamics
Congestive Heart Failure is a cardiovascular disease with global incidence and high mortality. In advanced stages, when patients are already...
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Topology optimization for blood flow considering a hemolysis model
In the past years, topology optimization has been studied for designing fluid flow devices, such as channels, valves and pumps, and also considering...
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Hemolysis estimation in turbulent flow for the FDA critical path initiative centrifugal blood pump
Hemolysis in medical devices and implants has been a primary concern over the past fifty years. Turbulent flow in particular can cause cell trauma...
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Numerical investigation of volute tongue design on hemodynamic characteristics and hemolysis of the centrifugal blood pump
In the design of rotary blood pumps, the optimization of design parameters plays an essential role in enhancing the hydrodynamic performance and...
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Multiscale modeling of hemolysis during microfiltration
In this paper, we propose a multiscale numerical algorithm to simulate the hemolytic release of hemoglobin (Hb) from red blood cells (RBCs) flowing...
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A Numerical Simulation of Reciprocating Blood Pump: Effect of Valve Movement and Leakage Flow on Hemolytic Performance
The left ventricular assist device (LVAD) is a blood pump that boosts the pum** ability of the bottom left chamber of the heart in patients with...
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Large-Eddy Simulations of Flow in the FDA Benchmark Nozzle Geometry to Predict Hemolysis
PurposeModeling of hemolysis due to fluid stresses faces significant methodological challenges, particularly in geometries with turbulence or complex...
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Investigating Dielectric Properties of Hemolysis by Electrical Impedance Spectroscopy
This paper presents a study toward the investigation of electrical properties of static bovine blood samples during hemolysis by electrochemical...
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Investigation of Two Newly Designed Ventricular Assist Device Models
Over the years, ventricular assist devices (VADs) have helped save and prolong the lives of thousands of patients with end-stage heart failure....
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Optimization of geometric indicators of a ventricular pump using computational fluid dynamics, surrogate model, response surface approximation, kriging and particle swarm optimization algorithm
A ventricular pump is a device used to treat patients with heart failure. In this device, the blood pressure is very important. On the other hand,...
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Evaluation of Hemolytic Behavior and Bioactive Properties of Natural Wollastonite and Synthetic Hydroxyapatites Produced by Two Sol-Gel Routes
Bioactive properties and hemolytic behavior of sintered bioceramics of natural wollastonite and synthetic hydroxyapatites (B-type carbonated...
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An energy-dissipation-based power-law formulation for estimating hemolysis
Hemolysis is a major concern in blood-circulating devices, which arises due to non-physiological stresses on red blood cells from ambient flow...
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Effect of flow rate ratio and positioning on a lighthouse tip ECMO return cannula
Extracorporeal membrane oxygenation is a life-saving support therapy in the case of cardiopulmonary refractory failure. Its use is associated to...
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Contraction of the rigor actomyosin complex drives bulk hemoglobin expulsion from hemolyzing erythrocytes
Erythrocyte ghost formation via hemolysis is a key event in the physiological clearance of senescent red blood cells (RBCs) in the spleen. The...
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Patient-specific bicuspid aortic valve hemodynamics study based on computer simulation and in vitro experiment
Bicuspid aortic valve (BAV) is a common congenital malformation of the aortic valve with various structural characteristics. Different types of BAV...
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Green Synthesis of Silver Nanoparticles from Spirulina platensis Extract: Antibacterial and Antioxidant Potential
The development of nanoparticles derived from noble metals has garnered significant attention in recent years, particularly with gold and silver...
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Blood flow topology optimization considering a thrombosis model
In the field of topology optimization for fluid flow design, there is a specific class of formulations directed to non-Newtonian fluids. One...
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Biological properties of surface modified 316 LVM steel
This paper aimed to investigate the selected physicochemical and biological properties of titanium dioxide thin films deposited by atomic layer...
