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RETRACTED ARTICLE: Screening of feature genes related to immune and inflammatory responses in periodontitis
BackgroundImmune and inflammatory responses are important in the occurrence and development of periodontitis. The aim of this study was to screen for...
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Identification and assessment of differentially expressed necroptosis long non-coding RNAs associated with periodontitis in human
BackgroundPeriodontitis is the most common oral disease and is closely related to immune infiltration in the periodontal microenvironment and its...
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A prognostic Risk Score model for oral squamous cell carcinoma constructed by 6 glycolysis-immune-related genes
BackgroundOral squamous cell carcinoma (OSCC) is the most frequent tumor of the head and neck. The glycolysis-related genes and immune-related genes...
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Multi-omics analysis of immune-related microbiome and prognostic model in head and neck squamous cell carcinoma
ObjectivesThe aim of our study is to explore the transcriptional and microbial characteristics of head and neck cancer’s immune phenotypes using a...
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Whole-transcriptome analysis of periodontal tissue and construction of immune-related competitive endogenous RNA network
BackgroundIn periodontitis, noncoding RNAs may play a regulatory role in the immune microenvironment through competitive endogenous RNA. We aimed to...
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Exploring the molecular mechanisms of ferroptosis-related genes in periodontitis: a multi-dataset analysis
PurposeThis study aims to elucidate the biological functions of ferroptosis-related genes in periodontitis, along with their correlation to tumor...
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Differentially expressed miRNAs associated with generalized aggressive periodontitis
ObjectiveThis study aimed to investigate miRNA expression profiles in individuals with periodontitis which is a chronic inflammatory condition...
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Prognostic model based on telomere-related genes predicts the risk of oral squamous cell carcinoma
BackgroundThis study investigated a potential prognostic model based on telomere-related genes (TRGs) for the clinical prediction of oral squamous...
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CD8 + T-cell marker genes reveal different immune subtypes of oral lichen planus by integrating single-cell RNA-seq and bulk RNA-sequencing
BackgroundOral lichen planus (OLP) is a local autoimmune disease induced by T-cell dysfunction that frequently affects middle-aged or elderly people,...
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Exploring the potential link between MitoEVs and the immune microenvironment of periodontitis based on machine learning and bioinformatics methods
BackgroundPeriodontitis is a chronic inflammatory condition triggered by immune system malfunction. Mitochondrial extracellular vesicles (MitoEVs)...
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Prediction of interactomic hub genes in PBMC cells in type 2 diabetes mellitus, dyslipidemia, and periodontitis
Background and objectiveIn recent years, the complex interplay between systemic health and oral well-being has emerged as a focal point for...
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Potential links between COVID-19 and periodontitis: a bioinformatic analysis based on GEO datasets
Background2019 Coronavirus disease (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)....
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The underlying molecular mechanisms and biomarkers between periodontitis and COVID-19
ObjectiveEmerging evidence shows the clinical consequences of patient with COVID-19 and periodontitis are not promising, and periodontitis is a risk...
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Molecular mechanism and diagnostic marker investigation of endoplasmic reticulum stress on periodontitis
PurposeThe aim of this study was to reveal the biological function of endoplasmic reticulum stress (ERS)-related genes (ERSGs) in periodontitis, and...
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Identification and validation of transcription factor-driven enhancers of genes related to lipid metabolism in metastatic oral squamous cell carcinomas
BackgroundThe role and mechanisms of lipid metabolism in oral squamous cell carcinomas (OSCC) metastasis have not been clarified. This study aims to...
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Temporal gene expression profiling during early-stage traumatic temporomandibular joint bony ankylosis in a sheep model
BackgroundInvestigating the molecular biology underpinning the early-stage of traumatic temporomandibular joint (TMJ) ankylosis is crucial for...
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Identification of key module and hub genes in pulpitis using weighted gene co-expression network analysis
BackgroundPulpitis is a common disease mainly caused by bacteria. Conventional approaches of diagnosing the state of dental pulp are mainly based on...
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CTHRC1 is a prognostic biomarker correlated with immune infiltration in head and neck squamous cell carcinoma
BackgroundHead and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, characterized by high morbidity, high...
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Identification of the characteristics of infiltrating immune cells in pulpitis and its potential molecular regulation mechanism by bioinformatics method
ObjectiveThe inflammation of dental pulp will also trigger an immune response. The purpose of this study is to demonstrate the immune cell’s function...
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Identification of Immune Infiltration in Odontogenic Keratocyst by Integrated Bioinformatics Analysis
BackgroundOdontogenic keratocyst (OKC) is a relatively common odontogenic lesion characterized by local invasion in the maxillary and mandibular...