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Showing 1-20 of 173 results
  1. RETRACTED ARTICLE: Screening of feature genes related to immune and inflammatory responses in periodontitis

    Background

    Immune and inflammatory responses are important in the occurrence and development of periodontitis. The aim of this study was to screen for...

    Azhu Duan, Yeming Zhang, Gongjie Yuan in BMC Oral Health
    Article Open access 21 April 2023
  2. Identification and assessment of differentially expressed necroptosis long non-coding RNAs associated with periodontitis in human

    Background

    Periodontitis is the most common oral disease and is closely related to immune infiltration in the periodontal microenvironment and its...

    Jiangfeng He, Zhanglong Zheng, ... Yongming Li in BMC Oral Health
    Article Open access 04 September 2023
  3. A prognostic Risk Score model for oral squamous cell carcinoma constructed by 6 glycolysis-immune-related genes

    Background

    Oral squamous cell carcinoma (OSCC) is the most frequent tumor of the head and neck. The glycolysis-related genes and immune-related genes...

    Yi Liu, Tong Wang, Ronghua Li in BMC Oral Health
    Article Open access 03 August 2022
  4. Multi-omics analysis of immune-related microbiome and prognostic model in head and neck squamous cell carcinoma

    Objectives

    The aim of our study is to explore the transcriptional and microbial characteristics of head and neck cancer’s immune phenotypes using a...

    Yingqiao Liu, Haitao Lin, ... **qiang Liu in Clinical Oral Investigations
    Article Open access 20 April 2024
  5. Whole-transcriptome analysis of periodontal tissue and construction of immune-related competitive endogenous RNA network

    Background

    In periodontitis, noncoding RNAs may play a regulatory role in the immune microenvironment through competitive endogenous RNA. We aimed to...

    Quanquan Zhao, **g Wen, ... **nzhe Lou in BMC Oral Health
    Article Open access 31 August 2022
  6. Exploring the molecular mechanisms of ferroptosis-related genes in periodontitis: a multi-dataset analysis

    Purpose

    This study aims to elucidate the biological functions of ferroptosis-related genes in periodontitis, along with their correlation to tumor...

    Jili Chen, Lijia Ou, ... Feng Gao in BMC Oral Health
    Article Open access 27 May 2024
  7. Differentially expressed miRNAs associated with generalized aggressive periodontitis

    Objective

    This study aimed to investigate miRNA expression profiles in individuals with periodontitis which is a chronic inflammatory condition...

    Esra Guzeldemir-Akcakanat, Deniz Sunnetci-Akkoyunlu, ... Naci Cine in Clinical Oral Investigations
    Article 21 December 2023
  8. Prognostic model based on telomere-related genes predicts the risk of oral squamous cell carcinoma

    Background

    This study investigated a potential prognostic model based on telomere-related genes (TRGs) for the clinical prediction of oral squamous...

    Kun Yue, Xue Yao in BMC Oral Health
    Article Open access 14 July 2023
  9. CD8 + T-cell marker genes reveal different immune subtypes of oral lichen planus by integrating single-cell RNA-seq and bulk RNA-sequencing

    Background

    Oral lichen planus (OLP) is a local autoimmune disease induced by T-cell dysfunction that frequently affects middle-aged or elderly people,...

    **hao Zhang, Gaoge Peng, ... Gang Tian in BMC Oral Health
    Article Open access 08 July 2023
  10. Exploring the potential link between MitoEVs and the immune microenvironment of periodontitis based on machine learning and bioinformatics methods

    Background

    Periodontitis is a chronic inflammatory condition triggered by immune system malfunction. Mitochondrial extracellular vesicles (MitoEVs)...

    Haoran Yang, Anna Zhao, ... Ziliang Li in BMC Oral Health
    Article Open access 02 February 2024
  11. Prediction of interactomic hub genes in PBMC cells in type 2 diabetes mellitus, dyslipidemia, and periodontitis

    Background and objective

    In recent years, the complex interplay between systemic health and oral well-being has emerged as a focal point for...

    Pradeep kumar yadalam, Deepavalli Arumuganainar, ... Giuseppe Minervini in BMC Oral Health
    Article Open access 26 March 2024
  12. Potential links between COVID-19 and periodontitis: a bioinformatic analysis based on GEO datasets

    Background

    2019 Coronavirus disease (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)....

    Churen Zhang, Yuzhe Sun, ... Dongchen Ou in BMC Oral Health
    Article Open access 21 November 2022
  13. The underlying molecular mechanisms and biomarkers between periodontitis and COVID-19

    Objective

    Emerging evidence shows the clinical consequences of patient with COVID-19 and periodontitis are not promising, and periodontitis is a risk...

    Danlei Qin, Feiyan Yu, ... Bin Zhao in BMC Oral Health
    Article Open access 26 July 2023
  14. Molecular mechanism and diagnostic marker investigation of endoplasmic reticulum stress on periodontitis

    Purpose

    The aim of this study was to reveal the biological function of endoplasmic reticulum stress (ERS)-related genes (ERSGs) in periodontitis, and...

    Qianqian Sun, Enqiang Zhu in BMC Oral Health
    Article Open access 09 March 2023
  15. Identification and validation of transcription factor-driven enhancers of genes related to lipid metabolism in metastatic oral squamous cell carcinomas

    Background

    The role and mechanisms of lipid metabolism in oral squamous cell carcinomas (OSCC) metastasis have not been clarified. This study aims to...

    Liru Zhang, Shuangling Zhao, ... **xue Geng in BMC Oral Health
    Article Open access 15 April 2022
  16. Temporal gene expression profiling during early-stage traumatic temporomandibular joint bony ankylosis in a sheep model

    Background

    Investigating the molecular biology underpinning the early-stage of traumatic temporomandibular joint (TMJ) ankylosis is crucial for...

    Tong-Mei Zhang, Kun Yang, ... Ying-Bin Yan in BMC Oral Health
    Article Open access 28 February 2024
  17. Identification of key module and hub genes in pulpitis using weighted gene co-expression network analysis

    Background

    Pulpitis is a common disease mainly caused by bacteria. Conventional approaches of diagnosing the state of dental pulp are mainly based on...

    Denghui Zhang, Chen Zheng, ... Yiqun Zhou in BMC Oral Health
    Article Open access 02 January 2023
  18. CTHRC1 is a prognostic biomarker correlated with immune infiltration in head and neck squamous cell carcinoma

    Background

    Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, characterized by high morbidity, high...

    Zhichao Zhang, Xusheng Ren, ... Chao Xu in BMC Oral Health
    Article Open access 27 June 2024
  19. Identification of the characteristics of infiltrating immune cells in pulpitis and its potential molecular regulation mechanism by bioinformatics method

    Objective

    The inflammation of dental pulp will also trigger an immune response. The purpose of this study is to demonstrate the immune cell’s function...

    **g Wang, Junxia Qiao, ... Kun Liu in BMC Oral Health
    Article Open access 13 May 2023
  20. Identification of Immune Infiltration in Odontogenic Keratocyst by Integrated Bioinformatics Analysis

    Background

    Odontogenic keratocyst (OKC) is a relatively common odontogenic lesion characterized by local invasion in the maxillary and mandibular...

    Nian-Nian Zhong, Su-Ran Li, ... Bing Liu in BMC Oral Health
    Article Open access 06 July 2023
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