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CTHRC1 is a prognostic biomarker correlated with immune infiltration in head and neck squamous cell carcinoma
BackgroundHead and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, characterized by high morbidity, high...
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CD79A work as a potential target for the prognosis of patients with OSCC: analysis of immune cell infiltration in oral squamous cell carcinoma based on the CIBERSORTx deconvolution algorithm
ObjectiveTo analyze the abundance of infiltrating tumor immune cells in patients with oral squamous cell carcinoma (OSCC) and to search for potential...
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Single cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratification
Head and neck squamous cell carcinoma (HNSCC) is characterized by high recurrence or distant metastases rate and the prognosis is challenging. There...
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Identification of Immune Infiltration in Odontogenic Keratocyst by Integrated Bioinformatics Analysis
BackgroundOdontogenic keratocyst (OKC) is a relatively common odontogenic lesion characterized by local invasion in the maxillary and mandibular...
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Exploring the molecular mechanisms of ferroptosis-related genes in periodontitis: a multi-dataset analysis
PurposeThis study aims to elucidate the biological functions of ferroptosis-related genes in periodontitis, along with their correlation to tumor...
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Aberrated PSMA1 expression associated with clinicopathological features and prognosis in oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) is a globally prevalent cancer with significant mortality rates. OSCC a predominant subtype of head and neck...
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CERCAM is a prognostic biomarker associated with immune infiltration of macrophage M2 polarization in head and neck squamous carcinoma
PurposeThis study aimed to investigate the relevance of cerebral endothelial cell adhesion molecule (CERCAM) expression to head and neck squamous...
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Increased SEC14L2 expression is associated with clinicopathological features and worse prognosis in oral squamous cell carcinoma
Abnormal expression of SEC14L2 has been implicated in many human cancers. However, the role of SEC14L2 in oral squamous cell carcinoma (OSCC) remains...
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Identification of the characteristics of infiltrating immune cells in pulpitis and its potential molecular regulation mechanism by bioinformatics method
ObjectiveThe inflammation of dental pulp will also trigger an immune response. The purpose of this study is to demonstrate the immune cell’s function...
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Spatial transcriptomics reveals that metabolic characteristics define the tumor immunosuppression microenvironment via iCAF transformation in oral squamous cell carcinoma
Tumor progression is closely related to tumor tissue metabolism and resha** of the microenvironment. Oral squamous cell carcinoma (OSCC), a...
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Multi-omics analysis of immune-related microbiome and prognostic model in head and neck squamous cell carcinoma
ObjectivesThe aim of our study is to explore the transcriptional and microbial characteristics of head and neck cancer’s immune phenotypes using a...
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Whole-transcriptome analysis of periodontal tissue and construction of immune-related competitive endogenous RNA network
BackgroundIn periodontitis, noncoding RNAs may play a regulatory role in the immune microenvironment through competitive endogenous RNA. We aimed to...
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The neutrophil–osteogenic cell axis promotes bone destruction in periodontitis
The immune-stromal cell interactions play a key role in health and diseases. In periodontitis, the most prevalent infectious disease in humans,...
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RFC3 serves as a novel prognostic biomarker and target for head and neck squamous cell carcinoma
ObjectiveHead and neck squamous cell carcinoma (HNSCC) is a prevalent cancer that originates from the squamous cells. The role of the replication...
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Interferon-γ induces immunosuppression in salivary adenoid cystic carcinoma by regulating programmed death ligand 1 secretion
Interferon-γ (IFN-γ), a key effector molecule in anti-tumor immune response, has been well documented to correlate with the intratumoral infiltration...
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Molecular mechanism and diagnostic marker investigation of endoplasmic reticulum stress on periodontitis
PurposeThe aim of this study was to reveal the biological function of endoplasmic reticulum stress (ERS)-related genes (ERSGs) in periodontitis, and...
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A novel hypoxia-associated gene signature for prognosis prediction in head and neck squamous cell carcinoma
BackgroundHead and neck squamous cell carcinoma (HNSCC) is the most common malignant tumor of head and neck, which seriously threatens human life and...
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CD8 + T-cell marker genes reveal different immune subtypes of oral lichen planus by integrating single-cell RNA-seq and bulk RNA-sequencing
BackgroundOral lichen planus (OLP) is a local autoimmune disease induced by T-cell dysfunction that frequently affects middle-aged or elderly people,...
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Early tissue and healing responses after maxillary sinus augmentation using horizontal platelet rich fibrin bone blocks
BackgroundThe effects of horizontal platelet-rich fibrin (H-PRF) bone block on the healing and immune response during sinus augmentation have not...
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Potential for treatment benefit of STING agonists plus immune checkpoint inhibitors in oral squamous cell carcinoma
BackgroundDNA-sensing receptor cyclic GMP–AMP synthase (cGAS) and its downstream signaling effector stimulator of interferon genes (STING) present a...
