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N-Alkylation/Arylation of Indole-3-Carboxaldehyde and Gelatin Functionalization via Schiff Base Formation
In the pursuit of advancing indole-based potential bioactive materials, the present work focuses on synthesizing indole-3-carboxaldehyde derivatives...
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Insights of Indole: A Novel Target in Medicinal Chemistry (A Review)
AbstractCancer accounts for ten million dies in each year. There are ample number of Food and Drug Administration (FDA) approved drugs for this...
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Collective Synthesis of Monoterpenoid Indole Alkaloids Using Bioinspired Strategies
In recent years, collective total synthesis, in which natural products are synthesized exhaustively from common intermediates, has attracted...
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Indole as a Versatile Building Block in Cycloaddition Reactions: Synthesis of Diverse Heterocyclic Frameworks
Indole, a ubiquitous and structurally versatile aromatic compound, has emerged as a key player in the synthesis of diverse heterocyclic frameworks...
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Catalyst-Free Three-Component Synthesis of Novel Tetrahydrospiro[indole-3,3′-pyrazole] Derivatives
AbstractA series of new tetrahydrospiro[indole-3,3′-pyrazole]-4′-carboxylate derivatives were synthesized by three-component reaction of substituted...
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Condensation of Amino-thia- and Oxazoles with Indole and 4-Nitrobenzaldehyde under Mechanoactivation Conditions
AbstractThe reactions of isoxazol-3-amine, thiazol-2-amine, benzo[ d ]thiazol-2-amine with 4-nitrobenzaldehyde and indole in the absence of a solvent...
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A Frontier in Indole Chemistry: 1-Hydroxyindoles, 1-Hydroxytryptamines, and 1-Hydroxytryptophans
Many new members of the 1-hydroxyindole, -tryptamine, and -tryptophan families are prepared. They demonstrate totally different reactivities from...
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Synthesis of Spiro[indole-3,2′-pyrrole]triones by the Reaction of Pyrrolobenzoxazepinetriones with Enaminoketone
AbstractThe reaction of 3-aroylpyrrolo[1,2- a ][4,1]benzoxazepine-1,2,4-triones with 3-(cyclohexylamino)-5,5-dimethylcyclohex-2-en-1-one afforded...
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Synthesis and NMR spectra of [15N]indole
A method was developed for the synthesis of selectively labeled [ 15 N]indole, allowing to obtain the target product with high chemical and isotopic...
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Evidences of noncovalent interactions between indole and dichloromethane under different solvent conditions
ContextTheoretical investigation of indole (IND) and its binary combination with dichloromethane (DC) in various solvents were computed to track the...
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Design, Synthesis, and Antiarrhythmic Activity of New Indole-3-carboxamide Derivatives
AbstractThe hERG potassium channel has recently received increased scientific interest due to its association with arrhythmia and sudden death from...
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Catharanthus roseus Monoterpenoid Indole Alkaloid Pathway Engineering in Yeast
Catharanthus roseus (L) G. Don, commonly known as Madagascar periwinkle, is a plant renowned for its ability to produce a wide range of bioactive...
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Synthesis and characterization of PANI and PANI-indole copolymer and study of their antimalarial and antituberculosis activity
The preparation of polyaniline (PANI) and its copolymer with indole involved a chemical oxidative polymerization method, with benzene sulfonic acid...
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A review on indole-based colorimetric and fluorescence sensors for the detection of heavy metal ions
The release of a substantial amount of heavy metals into the environment has led to severe environmental pollution, with some metals posing extreme...
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Structural engineering on indole derivative for rechargeable organic lithium-ion battery
In the present work, the indole derivative, namely, 3,3′,3″-methane-triyl-tris-1H-indol (tris-Ind), is synthesized and characterized as an organic...
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Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast
Monoterpenoid indole alkaloids (MIAs) represent a large class of plant natural products with marketed pharmaceutical activities against a wide range...
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Theoretical study on the effect of H2O on the formation mechanism of NOx precursors during indole pyrolysis
The incineration technology of kitchen waste is one of the effective technologies to achieve the resource utilization of municipal solid waste....
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Synthesis and Antifungal Activity of Indole Derivatives
A total of 20 new indole analogs were synthesized and evaluated for biological activity against Sclerotinia sclerotiorum , Altenaria solani , Verticilliu...
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Visible-Light Mediated Reaction of Indole with Aryl Halides Using Porphyrin Photocatalyst: A Feasible Technique to Afford N-Functionalized Indoles
The expansion of novel techniques for the construction of C–N bond is a crucial task in synthetic chemistry, owing to involvement of nitrogenous...
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Indole-5,6-quinones display hallmark properties of eumelanin
Melanins are ubiquitous biopolymers produced from phenols and catechols by oxidation. They provide photoprotection, pigmentation and redox activity...
