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Organotin compound as an inhibitor of nitric oxide formation
The effect of antitumor and antimetastatic agent, triphenyltin (3,5-di- tert -butyl-4-hydroxyphenyl)thiolate (Me-5), on the in vitro activity of...
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Structural characterization, thermal, DFT, cytotoxicity, and antimetastatic properties of cocaine complexes with La(III), Er(III), and Yb(III)
AbstractReaction of cocaine (Cn) with Ln(III) chloride salts [where Ln = La(III), Er(III), and Yb(III)] afforded complexes of the [Ln(Cn)Cl(OH 2 ) 3 ].2C...
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Potential antitumor activity of garlic against colorectal cancer: focus on the molecular mechanisms of action
PurposeThe aim of this review is to highlight the potential of garlic phytoconstituents as antitumor agents in colorectal cancer management based on...
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In Silico Analysis of Anti-inflammatory Activity of Quercetin from M. calabura Fruit
The aim of the present study is to reveal the mechanism of quercetin compound from M. calabura fruit extract in anti-inflammatory reaction using in...
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Synergetic regulation of cancer cells and exhausted T cells to fight cold tumors with a fluorinated EGCG-based nanocomplex
Immune therapy that targets PD-L1 (programmed cell death-ligand 1) is attractive to augment immune response by breaking the programmed cell death-1...
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A systems biology investigation of curcumin potency against TGF-β-induced EMT signaling in lung cancer
Curcumin (diferuloylmethane) is bioactive phenolic compound which exerts diverse antimetastatic effect. Several studies have reported the...
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Recent Updates on Anticancer Activity of Betulin and Betulinic Acid Hybrids (A Review)
AbstractThe frequency of human being suffering from cancer is increasing annually throughout the world, but treatment of cancer is becoming more...
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High-performance thin-layer chromatography method development and validation for quantification of piperine in different extracts of Piper longum L. and its antioxidant activity
A selective, simple, and sensitive high-performance thin-layer chromatography (HPTLC) method was developed and validated for identification and...
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Pharmacological Properties of White Mulberry (Morus alba L.) Leaves: Suppressing Migratory and Invasive Activities Against A549 Lung Cancer Cells
Morus alba known as a white mulberry is a medicinal plant that has been used in food ingredients and traditional medicine. M. alba leaves contain...
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Eupatilin: Sources, Extraction, Derivatives, and Pharmacological Activity
Eupatilin (5,7-dihydroxy-3′,4′,6-trimethoxyflavone) is a pharmacologically active flavone obtained from several medicinal plants. Because it is a...
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Ginsenoside Rb1 Deters Cell Proliferation, Induces Apoptosis, Alleviates Oxidative Stress, and Antimetastasis in Oral Squamous Carcinoma Cells
There are numerous therapeutic applications for ginsenoside Rb1 (GRb1), the primary saponin derived from ginseng root. According to earlier research,...
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Synthesis and Anticancer Activity of 3,4,5-Trimethoxycinnamamide-Tethered 1,2,3-Triazole Derivatives
AbstractA series of novel 3,4,5-trimethoxycinnamamide-tethered 1,2,3-triazole derivatives were prepared by the click reaction of ( E )- N -(prop-2-yn-1-y...
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An Overview of Essential Oil Anticancer Activity
Cancer is considered a complex set of diseases, characterized by the spread of abnormal cells, with high heterogeneity and multiple molecular...
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Bryophytes: A Myriad Hue of Bio-resources with Therapeutic Potentialities
Bryophytes are one of the largest plant groups distributed all over the world comprising approximately about 25,000 species. They are considered as...
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Biomimetic nanoparticles blocking autophagy for enhanced chemotherapy and metastasis inhibition via reversing focal adhesion disassembly
BackgroundAutophagy is a conserved catabolic process, which plays an important role in regulating tumor cell motility and degrading protein...
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First Polynuclear Palladium Compounds [(C5H12NO)(PdCl3)]n and [(C10H16NO)2(Pd2Cl6)] with High Antitumor and Radioprotective Activity
AbstractPolymeric palladium complexes [(C 5 H 12 NO)(PdCl 3 )] n ( I ) and [(C 10 H 16 NO) 2 (Pd 2 Cl 6 )] ( II ) were synthesized for the first time and studied by...
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The Impact of Rosmarinic Acid on the Oxidative Stress Metabolism: Evaluation Protocol Based on Glutathione-Dependent and -Independent Antioxidant Enzymes
Phytochemicals are plant-based bioactive molecules produced by plants for their regular metabolism and to protect them against pathogens....
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Organometallic Anticancer Compounds: Novel Half-Sandwich Ru(II)- and Co(II)-Arene Complexes, Their Cytotoxicity, and Apoptosis-Inducing Activity in Liver Cancer Cells
AbstractOrganometallic complexes in many instances are characterised by potential anti-proliferative activity against different types of cancer...
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Bioactive Compounds and Biological Activities of Nepal Yam (Dioscorea deltoidea wall. Ex Griseb.)
A better nutrient composition in food is always preferred for human health. Dioscorea deltoidea wall. Ex Griseb. has significantly influenced the...
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Environmental Toxicity of Engineered Carbon Nanoparticles
The employment of nanotechnological tools is increasing at a very rapid pace in modern agricultural systems. Among a gamut of nanoparticles employed,...