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Efficient production of 1,2,4-butanetriol from corn cob hydrolysate by metabolically engineered Escherichia coli
Corn cob is a major waste mass-produced in corn agriculture. Corn cob hydrolysate containing xylose, arabinose, and glucose is the hydrolysis product...
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Microbial Production of C2-C5 Diols
Diols are a category of important value-added chemicals, widely used in solvents, cosmetics, pharmaceuticals, and polymer industry. Production of...
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The Weimberg pathway: an alternative for Myceliophthora thermophila to utilize d-xylose
BackgroundWith d -xylose being the second most abundant sugar in nature, its conversion into products could significantly improve biomass-based...
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Co-utilization of glucose and xylose for the production of poly-β-hydroxybutyrate (PHB) by Sphingomonas sanxanigenens NX02
BackgroundPoly-β-hydroxybutyrate (PHB), produced by a variety of microbial organisms, is a good substitute for petrochemically derived plastics due...
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Efficient Preparation of Xylonic Acid from Xylonate Fermentation Broth by Bipolar Membrane Electrodialysis
Preparation of xylonic acid from xylonate fermentation broth was studied in a four-chamber bipolar membrane electrodialysis (BMED) setup. The effects...
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Rational protein engineering of a ketoacids decarboxylase for efficient production of 1,2,4-butanetriol from arabinose
BackgroundLignocellulose, the most abundant non-edible feedstock on Earth, holds substantial potential for eco-friendly chemicals, fuels, and...
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Structure and function of aldopentose catabolism enzymes involved in oxidative non-phosphorylative pathways
Platform chemicals and polymer precursors can be produced via enzymatic pathways starting from lignocellulosic waste materials. The hemicellulose...
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Metabolic Engineering of the Shikimic Acid Pathway in Escherichia coli for Production of Derived Aromatic Compounds
The microbial production of aromatic compounds derived from various intermediates of the shikimic acid (SHK) pathway comprise a great diversity of...
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Efficient aerobic fermentation of gluconic acid by high tension oxygen supply strategy with reusable Gluconobacter oxydans HG19 cells
Gluconic acid is a widely used food and beverage additive, but its production suffers from low efficiency and high cost. In this study, a preferable...
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Biosynthesis of fragrance 2-phenylethanol from sugars by Pseudomonas putida
BackgroundPetrochemicals contribute to environmental issues, with concerns ranging from energy consumption and carbon emission to pollution. In...
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Efficient lactic acid production from dilute acid-pretreated lignocellulosic biomass by a synthetic consortium of engineered Pseudomonas putida and Bacillus coagulans
BackgroundLignocellulosic biomass is an attractive and sustainable alternative to petroleum-based feedstock for the production of a range of...
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Enhanced glycolic acid yield through xylose and cellobiose utilization by metabolically engineered Escherichia coli
Microbial biorefinery is a promising route toward sustainable production of glycolic acid (GA), a valuable raw material for various industries....
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Applications of Genome Editing in Extremophiles
The member of bacteria, archaea, and eukarya comes under the umbrella of extremophiles. Extremophiles can survive in the extremely harsh conditions...
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Engineering microbial pathways for production of bio-based chemicals from lignocellulosic sugars: current status and perspectives
Lignocellulose is the most abundant biomass on earth with an annual production of about 2 × 10 11 tons. It is an inedible renewable carbonaceous...
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Increasing cellular fitness and product yields in Pseudomonas putida through an engineered phosphoketolase shunt
BackgroundPseudomonas putida has received increasing interest as a cell factory due to its remarkable features such as fast growth, a versatile and...
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Enhancement of Gluconobacter oxydans Resistance to Lignocellulosic-Derived Inhibitors in Xylonic Acid Production by Overexpressing Thioredoxin
Efficient utilization of lignocellulose is an economically relevant practice for improving the financial prospects of biorefineries. Lignocellulose...
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Recent Advances in Systems Metabolic Engineering Strategies for the Production of Biopolymers
Biopolymers consisting of at least one monomer, which are produced from renewable carbon sources, are being highly sought out since ubiquitous...
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Biochemical routes for uptake and conversion of xylose by microorganisms
Xylose is a major component of lignocellulose and the second most abundant sugar present in nature. Efficient utilization of xylose is required for...
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Microbial Production of Amine Chemicals from Sustainable Substrates
With global population projected to be almost 10 billion people by 2050, the demand for food, chemicals and energy is expected to rise continuously....
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Engineering of glycerol utilization in Gluconobacter oxydans 621H for biocatalyst preparation in a low-cost way
BackgroundWhole cells of Gluconobacter oxydans are widely used in various biocatalytic processes. Sorbitol at high concentrations is commonly used...
