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A novel nanobody-heavy chain antibody against Angiopoietin-like protein 3 reduces plasma lipids and relieves nonalcoholic fatty liver disease
BackgroundNonalcoholic fatty liver disease (NAFLD) is a metabolic disease mainly on account of hypercholesterolemia and may progress to cirrhosis and...
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Extraction of raspberry ketone from red raspberry and its intervention in the non-alcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is characterized by diffused hepatocyte bullous fat in the liver, which is not caused by alcohol or drugs...
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Effects of SCFAs and TMAO on non-alcoholic fatty liver disease indicating the therapeutic benefits of plant-based diet, and supplemental prebiotics, probiotics and synbiotics
This review discusses the effects of short-chain fatty acids (SCFAs) and trimethylamine-N-oxide (TMAO) on metabolic diseases, focusing on...
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Dietary intake of specific amino acids and liver status in subjects with nonalcoholic fatty liver disease: fatty liver in obesity (FLiO) study
PurposeIdentification of dietary factors involved in the development and progression of nonalcoholic fatty liver disease (NAFLD) is relevant to the...
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A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis
Our study aimed to explore the function of circRNA_0001805 in the pathogenesis of NAFLD and the underlying mechanism. A nanodrug system (GA-RM/GZ/PL)...
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Hepatoprotective Efficacy of Cinnamon
The liver is one of the five organs of the human body with a metabolic function in humans. From the perspective of metabolism, the main functions of...
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Bile acid-based polydrug nanoparticles for the treatment of acute liver injury
Acute liver failure and non-alcoholic fatty liver disease (NAFLD) are a common chronic liver disease worldwide, causing tremendous clinical burden....
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Habitual coffee intake and risk for nonalcoholic fatty liver disease: a two-sample Mendelian randomization study
PurposeEpidemiological studies support a protective role of habitual coffee and caffeine consumption against the risk of non-alcoholic fatty liver...
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Omega-3 Polyunsaturated Fatty Acids
The international urge to bridge the gap of providing substantial sources of omega-3 (ω-3) polyunsaturated fatty acids (PUFAs)-rich oils rather than...
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Omega-3 Polyunsaturated Fatty Acids
The international urge to bridge the gap of providing substantial sources of omega-3 (ω-3) polyunsaturated fatty acids (PUFAs)-rich oils rather than...
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LncRNA HOTAIR accelerates free fatty acid-induced inflammatory response in HepG2 cells by recruiting SRSF1 to stabilize MLXIPL mRNA
LncRNA HOTAIR has been reported to be associated with metabolic diseases of the liver. However, the effect of HOTAIR on non-alcoholic fatty liver...
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Obesity: A Disease of Overnutrition
Obesity is a serious worldwide problem that is increasing in prevalence. Obesity results from increased energy intake from food exceeding what is...
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Hepatitis
This chapter introduces the effects of arabinoxylan rice bran (Biobran) on hepatitis in animals and humans based on evidence-based research papers....
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Histopathological Evaluation of Steatohepatitis in Animal Experiments
Fatty liver is a medical condition in which excessive neutral fats accumulate in the liver; its main causes are nonalcoholic fatty liver disease...
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Isolation of the Hepatic Ubiquitome/NEDDylome by Streptavidin Pull-Down Assay in the Biotinylated Ubiquitin (bioUb)/Biotinylated NEDD8 (bioNEDD8) Transgenic Mice
In the last years, our group and others have uncovered the role of ubiquitin (Ub) and ubiquitin-like proteins such as the neural precursor cell...
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Improving the ameliorative effects of berberine and curcumin combination via dextran-coated bilosomes on non-alcohol fatty liver disease in mice
BackgroundThe combination of berberine (BER) and curcumin (CUR) has been verified with ameliorative effects on non-alcohol fatty liver disease...
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Multidisciplinary lifestyle intervention is associated with improvements in liver damage and in surrogate scores of NAFLD and liver fibrosis in morbidly obese patients
PurposeNon-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome. Particularly morbidly obese patients are at...
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Nanomaterials and hepatic disease: toxicokinetics, disease types, intrinsic mechanisms, liver susceptibility, and influencing factors
The widespread use of nanomaterials (NMs) has raised concerns that exposure to them may introduce potential risks to the human body and environment....
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2D-DIGE Proteomic Analysis of Mouse Liver Within 1 Week
Several years have passed since LC (liquid chromatography)-MS (mass spectrometry) became the mainstream for proteomic analysis; however, conventional...
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Associations of dietary advanced glycation end products with liver steatosis via vibration controlled transient elastography in the United States: a nationwide cross-sectional study
PurposeLarge population-based studies for the associations between dietary advanced glycation end products (dAGEs) intake and liver steatosis remain...
