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Dendritic cell hybrid nanovaccine for mild heat inspired cancer immunotherapy
Cancer therapeutic vaccine can induce antigen-specific immune response, which has shown great potential in cancer immunotherapy. As the key factor of...
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Nanovaccine
In recent years, there have been numerous breakthroughs in the treatment of diseases in aquaculture. Progressive developments in nanotechnology have...
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Smart responsive Fe/Mn nanovaccine triggers liver cancer immunotherapy via pyroptosis and pyroptosis-boosted cGAS-STING activation
BackgroundThe prognosis for hepatocellular carcinoma (HCC) remains suboptimal, characterized by high recurrence and metastasis rates. Although...
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Nanovaccine-based strategies for lymph node targeted delivery and imaging in tumor immunotherapy
Therapeutic tumor vaccines have attracted considerable attention in the past decade; they can induce tumor regression, eradicate minimal residual...
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A "trained immunity" inducer-adjuvanted nanovaccine reverses the growth of established tumors in mice
Innate immune cells are critical in antitumor immune surveillance and the development of antitumor adaptive cellular immunity. Trained innate immune...
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Splenic-targeting biomimetic nanovaccine for elevating protective immunity against virus infection
BackgroundThe prevalence of viral infectious diseases has become a serious threat to public safety, economic and social development. Vaccines have...
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Preparation of a Klebsiella pneumoniae conjugate nanovaccine using glycol-engineered Escherichia coli
BackgroundEngineered strains of Escherichia coli have been used to produce bioconjugate vaccines using Protein Glycan Coupling Technology (PGCT)....
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Delivery of nanovaccine towards lymphoid organs: recent strategies in enhancing cancer immunotherapy
With the in-depth exploration on cancer therapeutic nanovaccines, increasing evidence shows that the poor delivery of nanovaccines to lymphoid organs...
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Exploiting immunostimulatory mechanisms of immunogenic cell death to develop membrane-encapsulated nanoparticles as a potent tumor vaccine
Vaccine is one of the most promising strategies for cancer immunotherapy; however, there are no therapeutic cancer vaccine achieving significant...
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Lymph node-targeted neoantigen nanovaccines potentiate anti-tumor immune responses of post-surgical melanoma
BackgroundNeoantigens are considered ideal targets for immunotherapy, especially tumor vaccine, because of their strong specificity and...
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Immunologically effective poly(D-lactic acid) nanoparticle enhances anticancer immune response
Chiral materials with the same atomic compositions exhibit different chemical, physical, and biological properties because of their distinct spatial...
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Application of antigen presenting cell-targeted nanovaccine delivery system in rhabdovirus disease prophylactics using fish as a model organism
BackgroundTargeted delivery of virus-associated antigens to professional antigen-presenting cells (APCs) is considered as an efficient strategy to...
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A new polysaccharide platform constructs self-adjuvant nanovaccines to enhance immune responses
BackgroundNanovaccines have shown the promising potential in controlling and eradicating the threat of infectious diseases worldwide. There has been...
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Probiotic-derived amphiphilic exopolysaccharide self-assembling adjuvant delivery platform for enhancing immune responses
Enhancing immune response activation through the synergy of effective antigen delivery and immune enhancement using natural, biodegradable materials...
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Radial porous SiO2 nanoflowers potentiate the effect of antigen/adjuvant in antitumor immunotherapy
Here, we reported a cancer nanovaccine based on SiO 2 nanoflowers with a special radial pore structure, which greatly enhanced cross-presentation and...
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Polylactic-Co-glycolic Acid Polymer-Based Nano-Encapsulation Using Recombinant Maltoporin of Aeromonas hydrophila as Potential Vaccine Candidate
Aquaculture production has been incurring economic losses due to infectious diseases by opportunistic pathogens like Aeromonas hydrophila , a...
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Targeting lymph node delivery with nanovaccines for cancer immunotherapy: recent advances and future directions
Although cancer immunotherapy is a compelling approach against cancer, its effectiveness is hindered by the challenge of generating a robust and...
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Inhalable hybrid nanovaccines with virus-biomimetic structure boost protective immune responses against SARS-CoV-2 variants
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with different antigenic variants, has posed a significant threat to public...
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Functional nanovesicles displaying anti-PD-L1 antibodies for programmed photoimmunotherapy
BackgroundPhotoimmunotherapy is one of the most promising strategies in tumor immunotherapies, but targeted delivery of photosensitizers and...
