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Plasma metabolite profiles identify pediatric medulloblastoma and other brain cancer
Medulloblastoma is a malignancy of the central nervous system that occurs most frequently in childhood and is often difficult to diagnose due to its...
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The Circular RNA circSKA3 Facilitates the Malignant Biological Behaviors of Medulloblastoma via miR-520 h/CDK6 Pathway
Circular RNAs (circRNAs) are reported to participate in the development of diverse human malignancies. This work investigated the mechanism of...
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13-Cis Retinoic Acid Induces Neuronal Differentiation in Daoy (Medulloblastoma) Cells Through Epigenetic Regulation of Topoisomerase IIβ
Medulloblastoma (MB) is a malignant tumor of the cerebellum that occurs in children and infants. Abnormal neuronal differentiation can lead to brain...
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Electrochemical biosensing of circulating microRNA-21 in cerebrospinal fluid of medulloblastoma patients through target-induced redox signal amplification
Monitoring of cerebrospinal fluid (CSF) microRNAs (miRs) offers a promising option for the diagnosis and management of patients with central nervous...
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Lipidome signatures of metastasis in a transgenic mouse model of sonic hedgehog medulloblastoma
Medulloblastoma (MB), the most common malignant pediatric brain tumor, has high propensity to metastasize. Currently, the standard treatment for MB...
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Expression analysis and regulation of GLI and its correlation with stemness and metabolic alteration in human brain tumor
GLI gene-mediated hedgehog (Hh) signaling pathway plays a substantial role in brain cancer development and growth including glioblastoma multiforme...
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Biological characterization of the UW402, UW473, ONS-76 and DAOY pediatric medulloblastoma cell lines
Medulloblastoma (MB) is the most common malignant brain tumor in children. Recent advances in molecular technologies allowed to classify MB in 4...
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Molecular characterization of Wnt pathway and function of β-catenin overexpression in medulloblastoma cell lines
Medulloblastoma (MB) is the most common malignant childhood brain tumor. MB is currently classified into four molecular subgroups (Wnt, Shh, Group 3,...
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Ginkgetin: Advances on Resources, Bioactivity, and Pharmacology
Ginkgetin is the first known biflavonoid, isolated from the leaves of Ginkgo biloba L. after which it was named. It is a derivative of amentoflavone...
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Recent Advances and Therapeutic Strategies Using CRISPR Genome Editing Technique for the Treatment of Cancer
CRISPR genome editing technique has the potential to target cancer cells in a precise manner. The latest advancements have helped to address one of...
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Photonic Crystal–Based Nanoscale Multipurpose Biosensor for Detection of Brain Tumours, HIV, and Anaemia with High Sensitivity
A nanoscale-based 2D-photonic crystal (PhC) biosensor with silicon rods arranged in a triangular lattice structure is proposed in this work. The...
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Design of Split Ring Resonator Graphene Metasurface Sensor for Efficient Detection of Brain Tumor
Tumors, irregularities, and malignancies of the brain are deemed lethal. If brain cancer detection techniques are executed appropriately, precious...
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A perspective on PLGA encapsulated radio agents
Today, it is well known that radioactive nano systems, particularly radioactive nano particles (NPs) based on polymeric NPs possess great advantages...
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Cytoplasm protein GFAP magnetic beads construction and application as cell separation target for brain tumors
BackgroundIt is very important to develop a highly efficient cerebrospinal fluid (CSF) detection system with diagnosis and prediction function, for...
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Baicalin Relieves Airway Inflammation in COPD by Inhibiting miR-125a
To investigate the effects of Baicalin on the apoptosis of human bronchial epithelial cells (16HBE) induced by cigarette smoke extract (CSE) and the...
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Increased Pro-Apoptotic and Anti-Proliferative Activities of Simvastatin Encapsulated PCL-PEG Nanoparticles on Human Breast Cancer Adenocarcinoma Cells
Recently, Simvastatin (SIM) is received notable attention due to its anti-cancer properties. However, the lipophilicity feature of SIM restricted its...
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Investigation of in vitro HDAC 1 inhibitory activity of Curcuma longa L. extracts, isolated fractions and curcumin
Histone deacetylases are a group of enzymes that have been linked with various inflammatory, cancerous and hereditary diseases. In this study,...
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Role of Carbon Nanostructures as Nano-Theranostics Against Breast and Brain Cancer
Evolving as an efficient diagnostic as well as therapeutic, the theranostics approach is quite a naive field in the arena of clinical medicine. Even...
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Potential impact of tissue molecular heterogeneity on ambient mass spectrometry profiles: a note of caution in choosing the right disease model
This review provides a summary of known molecular alterations in commonly used cancer models and strives to stipulate how they may affect ambient...
