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Compositional and Morphological Analysis of Salt Stress Tolerant Mannitol-1-phosphate Dehydrogenase (mtlD)-Transgenic Potato Plants
Undesired effects often occur in genetically modified (GM) plants, especially during metabolite engineering. Nevertheless, conducting a comparative...
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Deciphering of the Mannitol Metabolism Pathway in Clostridium tyrobutyricum ATCC 25755 by Comparative Transcriptome Analysis
Clostridium tyrobutyricum has great potential for bio-based chemicals and biofuel production from mannitol; however, the mannitol metabolic pathway...
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Mannitol Production by Heterofermentative Lactic Acid Bacteria: a Review
Obesity, diabetes, and other cardiovascular diseases are directly related to the high consumption of processed sugars with high caloric content. The...
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Improvement in l-ornithine production from mannitol via transcriptome-guided genetic engineering in Corynebacterium glutamicum
Backgroundl -Ornithine is an important medicinal intermediate that is mainly produced by microbial fermentation using glucose as the substrate. To...
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Metabolic engineering of erythritol production from glycerol by Yarrowia lipolytica
Erythritol as a four-carbon polyol has been widely used in food, pharmaceutical and daily chemical industries with characteristics of low caloric...
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Tartrate Dehydrogenase in Bacillus Species: Deciphering Unique Catalytic Diversity Through Kinetic, Structural and Molecular Docking Analysis
Divergently evolved Tartrate dehydrogenase (TDH) exhibits multiple catalytic activities at a single active site; the enzyme from P. putida (pTDH)...
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Using osmotic stress to stabilize mannitol production in Synechocystis sp. PCC6803
BackgroundMannitol is a C(6) polyol that is used in the food and medical sector as a sweetener and antioxidant, respectively. The sustainable...
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A temperature dependent pilin promoter for production of thermostable enzymes in Thermus thermophilus
BackgroundEnzymes from thermophiles are of great interest for research and bioengineering due to their stability and efficiency. Thermophilic...
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From waste to health-supporting molecules: biosynthesis of natural products from lignin-, plastic- and seaweed-based monomers using metabolically engineered Streptomyces lividans
BackgroundTransforming waste and nonfood materials into bulk biofuels and chemicals represents a major stride in creating a sustainable bioindustry...
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In vivo Characterization of the Inducible Promoter System of 3-hydroxypropionic Dehydrogenase in Pseudomonas denitrificans
Here, we characterized a gene expression system induced by 3-hydroxypropionic acid (3-HP) in Pseudomonas denitrificans . The system consists of a...
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Metabolic engineering of Thermoanaerobacterium AK17 for increased ethanol production in seaweed hydrolysate
Sustainably produced renewable biomass has the potential to replace fossil-based feedstocks, for generation of biobased fuels and chemicals of...
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Evaluation of Pretreatment and GABA Production Using Levilactobacillus brevis Fermentation of the Seaweed Saccharina japonica
The seaweed has a high content of easily degradable carbohydrates, making it a potential substrate for the production of γ -aminobutyric acid (GABA)....
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Synbiotic Fermentation of Undaria pinnatifida and Lactobacillus brevis to Produce Prebiotics and Probiotics
It has been optimized thermal acid hydrolytic pretreatment and enzymatic saccharification ( E s) in flask culture of Undaria pinnatifida seaweed, which...
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Exploration of Trichoderma reesei as an alternative host for erythritol production
BackgroundErythritol, a natural polyol, is a low-calorie sweetener synthesized by a number of microorganisms, such as Moniliella pollinis . Yet, a...
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Efficient expression of heterologous genes by the introduction of the endogenous glyceraldehyde-3-phosphate dehydrogenase gene intron 1 in Ganoderma lucidum
BackgroundGanoderma lucidum , a well-known medicinal mushroom, has received wide attention as a promising cell factory for producing bioactive...
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Recent Advances in the Utilization of Brown Macroalgae as Feedstock for Microbial Biorefinery
A stable and economical supply of biomass is essential for meeting the increasing demand for bioproducts. In this regard, numerous studies on the...
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Metabolic engineering of Yarrowia lipolytica for thermoresistance and enhanced erythritol productivity
BackgroundFunctional sugar alcohols have been widely used in the food, medicine, and pharmaceutical industries for their unique properties. Among...
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Non-canonical d-xylose and l-arabinose metabolism via d-arabitol in the oleaginous yeast Rhodosporidium toruloides
R. toruloides is an oleaginous yeast, with diverse metabolic capacities and high tolerance for inhibitory compounds abundant in plant biomass...
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Electrochemical sensor based on ionic liquid for detection of lactose content in dairy products
This paper presents the development of an electrochemical sensor based on a modified ionic liquid, 3-Amine-N-[3-(N-pyrrole)propyl]imidazole bromide...
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Nitric oxide-driven modifications of lipoic arm inhibit α-ketoacid dehydrogenases
Pyruvate dehydrogenase complex (PDHC) and oxoglutarate dehydrogenase complex (OGDC), which belong to the mitochondrial α-ketoacid dehydrogenase...