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The simple method of lipolysis/lipogenesis balance assessment based on 14C isotope: advances and importance of pH control
Our study is devoted to the development of an optimal protocol for lipolysis and lipogenesis assessment using 14C-labeled glucose. We confirmed the...
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Rottlerin suppresses lipid accumulation by inhibiting de novo lipogenesis and adipogenesis via LRP6/mTOR/SREBP1C in 3T3-L1 adipocytes
Rottlerin is isolated from Mallotus japonicus , a plant rich in polyphenols. Rottlerin is a selective PKCδ-inhibitor and is also known as an uncoupler...
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Gryllus bimaculatus extract ameliorates high-fat diet-induced hyperglycemia and hyperlipidemia by inhibiting hepatic lipogenesis through AMPK activation
Insect-based food is increasingly used and is a sustainable protein source provided by eco-friendly breeding respecting the animal welfare. The...
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Asimina triloba (pawpaw) fruit extract suppresses adipocyte differentiation and lipogenesis-related protein expression in 3T3-L1 cells
Obesity is a health condition accompanied by life-threatening comorbidities; hence, there is an increasing need for anti-obesity agents. The...
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Cold stress combined with salt or abscisic acid supplementation enhances lipogenesis and carotenogenesis in Phaeodactylum tricornutum (Bacillariophyceae)
Compounds from microalgae such as ω3-fatty acids or carotenoid are commercially exploited within the pharmacology, nutraceutical, or cosmetic...
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A metabolic model of Lipomyces starkeyi for predicting lipogenesis potential from diverse low-cost substrates
BackgroundLipomyces starkeyi has been widely regarded as a promising oleaginous yeast with broad industrial application prospects because of its...
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A combination of rebaudioside A and neohesperidin dihydrochalcone suppressed weight gain by regulating visceral fat and hepatic lipid metabolism in ob/ob mice
Rebaudioside A (Reb A) and neohesperidin dihydrochalcone (NHDC) are known as intense sweeteners. This study aimed to examine the anti-obesity effects...
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Dehydrocostus lactone ameliorates lipid accumulation, insulin resistance, and endoplasmic reticulum stress in palmitate-treated hepatocytes
Fatty liver disease is caused by lipid accumulation in the liver, insulin resistance (IR), reactive oxygen species (ROS), and endoplasmic reticulum...
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Bioinformatics Analysis of miR-181a and Its Role in Adipogenesis, Obesity, and Lipid Metabolism Through Review of Literature
The miRNAs regulate various biological processes in the mammalian body system. The role of miR-181a in the development, progression, and expansion of...
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Anti-obesity effects of Lactiplantibacillus plantarum SKO-001 in high-fat diet-induced obese mice
PurposePrevious reports showed that some probiotics provide beneficial effects on various diseases including metabolic disorders. This study aimed to...
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Microbial Lipid Production from High Concentration of Volatile Fatty Acids via Trichosporon cutaneum for Biodiesel Preparation
Direct bioconversion of high concentration of volatile fatty acids (VFAs) into microbial lipid is challenging due to the aggravated cytotoxicity of...
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Hypolipidemic Effects of Soy Protein and Isoflavones in the Prevention of Non-Alcoholic Fatty Liver Disease- A Review
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and affects about 25% of the population globally. Obesity and...
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An Updated Review on KRAS Mutation in Lung Cancer (NSCLC) and Its Effects on Human Health
The largest cause of cancer-related fatalities worldwide is lung cancer. In its early stages, lung cancer often exhibits no signs or symptoms. Its...
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Regulated in Development and DNA Damage Response 1 Protects Hepatocytes Against Palmitate-induced Lipotoxicity
Obesity induces hepatic steatosis triggering hepatic injury by lipotoxicity and can progress to nonalcoholic fatty liver disease. Regulated in...
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Dansameum regulates hepatic lipogenesis and inflammation in vitro and in vivo
Although the clinical guidelines for nonalcoholic fatty liver disease (NAFLD) therapy recommended hepato-protection and exercise to reduce body...
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Antioxidant and lipid-reducing effects of Rosa rugosa root extract in 3T3-L1 cell
Rosa rugosa root is traditionally known to be effective in the treatment of diabetes in Korea. R. rugosa root-specific compounds also show...
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Theabrownin of raw and ripened pu-erh tea varies in the alleviation of HFD-induced obesity via the regulation of gut microbiota
PurposePu-erh tea can be classified into raw pu-erh tea and ripened pu-erh tea. Theabrownin (TB) is one of the major components of pu-erh tea. The...
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Betaine in ameliorating alcohol-induced hepatic steatosis
Alcohol-associated liver disease (AALD) is one of most common chronic liver diseases. Hepatic steatosis is the earliest stage in AALD pathological...
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Novel insights into salinity-induced lipogenesis and carotenogenesis in the oleaginous astaxanthin-producing alga Chromochloris zofingiensis: a multi-omics study
BackgroundChromochloris zofingiensis , a freshwater alga capable of synthesizing both triacylglycerol (TAG) and astaxanthin, has been receiving...
