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Iron Accumulation in Ferritin
Understanding the iron accumulation process in ferritin protein nanocages has remained a centerpiece in the field of iron...
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Reassembly Design of Ferritin Cages
The ferritin family is distributed in nearly all organisms and protects them from iron-induced oxidative damage. Besides, its highly symmetrical...
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Ferritin and iron supplements in gestational diabetes mellitus: less or more?
Iron metabolism has been found to be closely related to gestational diabetes mellitus (GDM). Excessive ferritin levels were shown to be related to an...
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A Generalized Method for Metal Fixation in Horse Spleen L-Ferritin Cage
The naturally occurring iron storage protein, ferritin, has been recognized as an important template for preparing inorganic nanomaterials by...
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A Novel Approach for Delivery of Ergosterol Within Ferritin Cage: Stability, Slow-Release Property, and Cholesterol-Lowering Effect After Simulated Gastrointestinal Digestion
Ergosterol possesses a variety of physiological activities, however, its application is limited due to its poor water solubility and...
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Laser-activable murine ferritin nanocage for chemo-photothermal therapy of colorectal cancer
Chemotherapy, as a conventional strategy for tumor therapy, often leads to unsatisfied therapeutic effect due to the multi-drug resistance and the...
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Generation of bioluminescent enzyme immunoassay for ferritin by single-chain variable fragment and its NanoLuc luciferase fusion
Ferritin, widely present in liver and spleen tissue, is considered as a serological biomarker for liver diseases and cancers. The detection of...
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Design of a gold clustering site in an engineered apo-ferritin cage
Water-soluble and biocompatible protein-protected gold nanoclusters (Au NCs) hold great promise for numerous applications. However, design and...
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Glioma-targeted oxaliplatin/ferritin clathrate reversing the immunosuppressive microenvironment through hijacking Fe2+ and boosting Fenton reaction
Glioma is easy to develop resistance to temozolomide (TMZ). TMZ-resistant glioma secretes interleukin-10 (IL-10) and transforming growth factor-β...
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Development of a liquid phase radioimmunoassay for the measurement of serum ferritin levels for the detection of Covid-19 in patients
The aim of this study was the development and analytically validation of a radioimmunoassay system for the measurement of the serum ferritin...
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Impact of doxorubicin-loaded ferritin nanocages (FerOX) vs. free doxorubicin on T lymphocytes: a translational clinical study on breast cancer patients undergoing neoadjuvant chemotherapy
Despite the advent of numerous targeted therapies in clinical practice, anthracyclines, including doxorubicin (DOX), continue to play a pivotal role...
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Self-assembling ferritin nanoparticles coupled with linear sequences from canine distemper virus haemagglutinin protein elicit robust immune responses
BackgroundCanine distemper virus (CDV), which is highly infectious, has caused outbreaks of varying scales in domestic and wild animals worldwide, so...
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Self-assembling ferritin-dendrimer nanoparticles for targeted delivery of nucleic acids to myeloid leukemia cells
BackgroundIn recent years, the use of ferritins as nano-vehicles for drug delivery is taking center stage. Compared to other similar nanocarriers, Arc...
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Conversion of ferritin ferrihydrite core to magnetite by gold ions binding and the derived nanoparticle formation
Inspired by the multi-functionalities of vegetal extracts, we first focused on develo** a new gold nanoparticle (AuNP) synthesis method using...
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Integrin α2β1-targeting ferritin nanocarrier traverses the blood–brain barrier for effective glioma chemotherapy
BackgroundFerritin, the natural iron storage protein complex, self-assembles into a uniform cage-like structure. Human H-ferritin (HFn) has been...
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A Method to Investigate the Mechanism of Charge Transport Across Bio-Molecular Junctions with Ferritin
To investigate the mechanisms of charge transport (CT) across biomolecular tunnel junctions, it is required to make electrical contacts by a...
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Factors associated with serum ferritin levels and iron excess: results from the EPIC-EurGast study
PurposeExcess iron is involved in the development of non-communicable diseases such as cancer, type 2 diabetes and cardiovascular conditions. We...
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Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC
BackgroundHepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis. Magnetic resonance imaging (MRI) is one of the most...
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Construction Protocol of Drug-Protein Cage Complexes for Drug Delivery System
Ferritin is one of the most promising drug delivery system (DDS) carriers because of its uniform nanosize, biodistribution, efficient cellular...
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Characterization of recombinant protein ferritin from Pyropia yezoensis (rPyFer) and its biological activities
Ferritins are iron-binding proteins that are basically participated in iron storage, detoxification, and immune response. In the present study,...
