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Develo** liver-targeted naringenin nanoparticles for breast cancer endocrine therapy by promoting estrogen metabolism
Endocrine therapy is standard for hormone receptor–positive (HR + ) breast cancer treatment. However, current strategies targeting estrogen signaling...
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Immunofluorescence Analysis of Estrogen Receptors Alpha Expression in Non-Small Cell Lung Cancer Tissue
AbstractA quantitative assessment of the expression of estrogen receptors alpha (ERα) is carried out in 115 samples of non-small cell lung cancer...
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Expression Significance of Estrogen Receptor ER-α36 in Breast Cancer Treated by Chemotherapy: A Meta-Analysis
Estrogen receptor (ER) is a molecular marker and target for diagnosing and treating breast cancer (BC). ER-α36, a novel estrogen receptor subtype,...
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Spectroscopic, DFT investigation and active site analysis of 2,2-diphenyl-1,3-propanediol against estrogen receptor EPR gamma
The compound 2,2-diphenyl-1,3-propanediol (22D13P) was very useful in the development of anti-breast cancer. The FT-IR, 13 C and 1 H-NMR spectra of...
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The Phytoestrogenic Effect of Hibiscus sabdariffa Involves Estrogen Receptor α in Ovariectomized Wistar Rats
The calyxes of Hibiscus sabdariffa present multiple pharmacological effects primarily attributed to their high anthocyanin content; however, little...
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Estrogenic activity of freeze-dried silkworm extracts through the activation of estrogen receptors in MCF-7 cells
Silkworm is an insect that feeds on mulberry leaves only, and silkworm powder has been reported to have antioxidant, hypoglycemic, and...
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CDFT-based chemical reactivity properties analysis of the fluorine substitution in the selective estrogen receptor modulator (SERM) Tamoxifen
In Mexico, breast cancer is the leading cause of cancer death among women. The growing increase in the disease is closely related to the aging of the...
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RETRACTED ARTICLE: Copper-based metal–organic framework impedes triple-negative breast cancer metastasis via local estrogen deprivation and platelets blockade
Metastasis is one of the main causes of failure in the treatment of triple-negative breast cancer (TNBC). Abnormally estrogen level and activated...
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Withania somnifera inhibits photorefractoriness which triggers neuronal apoptosis in both pre-optic and paraventricular hypothalamic area of Coturnix coturnix japonica: involvement of oxidative stress induced p53 dependent Caspase-3 mediated low immunoreactivity of estrogen receptor alpha
Light has a very important function in the regulation of the normal physiology including the neuroendocrine system, biological rhythms, cognitive...
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Estrogen Sulfotransferase is Highly Expressed in Vascular Endothelial Cells Overlying Atherosclerotic Plaques
Cytosolic estrogen sulfotransferase (SULT1E1) mainly catalyzes the sulfoconjugation and deactivation of estrogens that are known to exert potent...
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Protective effect of Pterospermum rubiginosum bark extract on bone mineral density and bone remodelling in estrogen deficient ovariectomized Sprague–Dawley (SD) rats
Osteoporosis is a common metabolic old age disorder characterised by low bone mass content (BMC) and mineral density (BMD) with micro-architectural...
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In silico docking and ADME study of deketene curcumin derivatives (DKC) as an aromatase inhibitor or antagonist to the estrogen-alpha positive receptor (Erα+): potent application of breast cancer
Regardless of many extensive studies, hormonal-based breast cancer is the most common cause of cancer-related mortality of females worldwide. Indeed,...
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Oxytocin Receptor Expression is Associated with Estrogen Receptor Status in Breast Tumors
The oxytocin receptor (OXTR) plays an important role in childbirth, breastfeeding, and social interactions. Increasing evidence exists that OXTR is...
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Interaction of Native- and Oxidized-Low-Density Lipoprotein with Human Estrogen Sulfotransferase
Cytosolic estrogen sulfotransferase (SULT1E) mainly catalyzes the sulfate conjugation of estrogens, which decrease atherosclerosis progression....
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microRNA-26b inhibits growth and cellular invasion of ovarian cancer cells by targeting estrogen receptor α
The current study set out to elucidate the mechanism of miR-26b in OC cell proliferation and EMT via suppression of ERα. Initial findings illustrated...
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Non-target estrogenic screening of 60 pesticides, six plant protection products, and tomato, grape, and wine samples by planar chromatography combined with the planar yeast estrogen screen bioassay
For non-target residue analysis of xenoestrogens in food, sophisticated chromatographic–mass spectrometric techniques lack in biological effect...
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Endocrine disruption: molecular interactions of chlorpyrifos and its degradation products with estrogen receptor
Chlorpyrifos is an extensively used organophosphate pesticide showing broad-spectrum effectiveness on various target pests. Long-term sublethal...
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Hyperoside ameliorates depression-like behavior in ovariectomized mice
The physiological changes caused by the decline in estrogen levels due to menopause are linked to an increased risk of depression. This study...
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Comparative Immunofluorescent Analysis of Estrogen Receptor Beta Expression in Ovarian and Breast Cancer Cell Lines
AbstractComparative quantitative evaluation of estrogen receptors β (ERβ) expression is performed by the immunofluorescence method using flow...
