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Design Principles for Biological Adaptation: A Systems and Control-Theoretic Treatment
Establishing a map** between (from and to) the functionality of interest and the underlying network structure (design principles) remains a crucial...
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Optimization of adaptation parameters from adhesion cell culture in serum-containing media to suspension in chemically defined media by superlative box design
A new design of experiments—superlative box design (SBD), was adopted to optimize the adaptation of Chinese hamster ovary cells from adhesion culture...
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Adaptation and Experimental Validation of Clinical RNA Sequencing Protocol Oncobox for MGI DNBSEQ-G50 Platform
AbstractRNA sequencing (RNAseq) is currently a method of choice for the high-throughput RNA-level analysis of gene expression. Furthermore, RNAseq...
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An Extensive Study on Silicon Role in Propagation of Thornless Blackberry (Rubus fruticosus, Merton cultivar) During In Vitro and Adaptation Phases
Silicon, as a beneficial element, can improve the growth and morphological characteristics of the plants propagated by tissue culture. The aim of...
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Protein production dynamics and physiological adaptation of recombinant Komagataella phaffii at near-zero growth rates
BackgroundSpecific productivity (q P ) in yeast correlates with growth, typically peaking at intermediate or maximum specific growth rates (μ)....
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Culture adaptation for enhanced biogas production from birch wood applying stable carbon isotope analysis to monitor changes in the microbial community
Birch wood is a potential feedstock for biogas production in Northern Europe; however, the lignocellulosic matrix is recalcitrant preventing...
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The healthy eating index for older adults: adaptation of the 2015 healthy eating index considering dietary guidelines for healthy aging
IntroductionThe Healthy Eating Index (HEI) is a comprehensive measure to assess diet quality. Because of the various factors that influence the...
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Small GTPase Rab7 is involved in stress adaptation to carbon starvation to ensure the induced cellulase biosynthesis in Trichoderma reesei
BackgroundThe saprophytic filamentous fungus Trichoderma reesei represents one of the most prolific cellulase producers. The bulk production of...
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Unveiling the persistent threat: recent insights into Listeria monocytogenes adaptation, biofilm formation, and pathogenicity in foodborne infections
Listeriosis is a severe disease caused by the foodborne pathogen Listeria monocytogenes , posing a significant risk to vulnerable populations such as...
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Determinants of adoption of small-scale irrigation practices as adaptation strategies to climate change stresses in Kersa District, Eastern Oromia, Ethiopia
This study was conducted to assess the factors influencing farmers’ decisions to adopt small-scale irrigation practices as an adaptation strategy to...
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Protein acetylation regulates xylose metabolism during adaptation of Saccharomyces cerevisiae
BackgroundAs the second most abundant polysaccharide in nature, hemicellulose can be degraded to xylose as the feedstock for bioconversion to fuels...
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Deciphering local adaptation of native Indian cattle (Bos indicus) breeds using landscape genomics and in-silico prediction of deleterious SNP effects on protein structure and function
India has 50 registered breeds of native cattle ( Bos indicus ) which are locally adapted to diverse environmental conditions. This study aimed to...
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Construction and Simulation of Digital Twin Model and Electrolyzer Wide Power Adaptation Model for Alkaline Electrolytic Water Hydrogen Production
Combining the framework of digital twin and the working mechanism of electrolytic water hydrogen production, a digital twin model of alkaline...
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Carbonic anhydrase IX-targeted H-APBC nanosystem combined with phototherapy facilitates the efficacy of PI3K/mTOR inhibitor and resists HIF-1α-dependent tumor hypoxia adaptation
BackgroundNon-redundant properties such as hypoxia and acidosis promote tumor metabolic adaptation and limit anti-cancer therapies. The key to the...
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Functionalization of curcumin nanomedicines: a recent promising adaptation to maximize pharmacokinetic profile, specific cell internalization and anticancer efficacy against breast cancer
Owing to its diverse heterogeneity, aggressive nature, enormous metastatic potential, and high remission rate, the breast cancer (BC) is among the...
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Adaptation on xylose improves glucose–xylose co-utilization and ethanol production in a carbon catabolite repression (CCR) compromised ethanologenic strain
BackgroundSugar hydrolysates from lignocellulosic biomass are majorly composed of glucose and xylose that can be fermented to biofuels. Bacteria,...
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Shatavari supplementation in postmenopausal women alters the skeletal muscle proteome and pathways involved in training adaptation
PurposeShatavari is an understudied, widely available herbal supplement. It contains steroidal saponins and phytoestrogens. We previously showed that...
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Impact of Climate Change on Food Security for Health Management and Its Adaptation Strategies for Sustainability among Households in South-East Nigeria
The study identified climate change and its impact on food security for health management, as well as its adaptation strategies for sustainability...
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Calorimetric adaptation of the inhibited autoxidation method to determine the activity of individual antioxidants and natural extracts
This work aims to determine the antioxidants activity of individual antioxidants and natural extracts by isothermal calorimetry. The proposed method...
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Evolution of biofilm-forming pathogenic bacteria in the presence of nanoparticles and antibiotic: adaptation phenomena and cross-resistance
BackgroundTreatment of bacterial biofilms are difficult and in many cases, expensive. Bacterial biofilms are naturally more resilient to...
