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Propionic and valproic acids have an impact on bacteria viability, proton flux and ATPase activity
Short-chain fatty acids like propionic (PPA) and valproic acids (VP) can alter gut microbiota, which is suggested to play a role in development of...
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Changes in ATPase activity, antioxidant enzymes and proline biosynthesis in yeast Candida guilliermondii NP-4 under X-irradiation
This study investigates the effects of X-radiation on ATPase activity and antioxidant enzyme activity, particularly enzymes involved in proline...
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Effect of nitrosyl iron complexes and their thio ligands on the activity of phosphodiesterase and sarcoplasmic reticulum Ca2+-ATPase
The effect of certain NO donors, viz. , nitrosyl iron complexes (NICs) and their functional thio ligands, on the activity of hydrolytic enzymes was...
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The effect of cytochrome c on Na,K-ATPase
Na,K-ATPase is a crucial enzyme responsible for maintaining Na + , K + -gradients across the cell membrane, which is essential for numerous physiological...
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Effect of H2O2 on Na,K-ATPase
Na,K-ATPase is a member of the P-type ATPase family, which transforms the energy of ATP to the transmembrane Na/K gradient that is used to create...
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Design of allosteric sites into rotary motor V1-ATPase by restoring lost function of pseudo-active sites
Allostery produces concerted functions of protein complexes by orchestrating the cooperative work between the constituent subunits. Here we describe...
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Analysis of cholesterol-recognition motifs of the plasma membrane Ca2+-ATPase
The plasma membrane Ca 2+ -ATPase (PMCA) is crucial for the fine tuning of intracellular calcium levels in eukaryotic cells. In this study, we show the...
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Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97
Biosensor techniques have become increasingly important for fragment-based drug discovery during the last years. The AAA+ ATPase p97 is an essential...
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Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Inhibitors Isolated from Subtropical Marine Cyanobacteria in Japan
Marine cyanobacteria are prolific producers of natural products with novel structures and potent biological activities. We have investigated the...
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Knockdown of capsid protein encoding novel ATPase domain inhibits genome packaging in potato leafroll virus
Potato leafroll virus (PLRV) uses powerful molecular machines to package its genome into a viral capsid employing ATP as fuel. Although, recent...
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Understanding Propofol’s Protective Mechanism in Tubular Epithelial Cells: Mitigating Pyroptosis via the miR-143-3p/ATPase Na + /K + Transporting Subunit Alpha 2 Pathway in Renal Ischemia–Reperfusion
Propofol (Pro), a prevalent intravenous anesthetic, has recently been recognized for its potential in mitigating ischemia–reperfusion (I/R) injuries....
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Heterologous production of the insecticidal pea seed albumin PA1 protein by Pichia pastoris and protein engineering to potentiate aphicidal activity via fusion to snowdrop lectin Galanthus nivalis agglutinin; GNA)
BackgroundNew bioinsecticides with novel modes of action are urgently needed to minimise the environmental and safety hazards associated with the use...
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External succinate and potassium ions influence Dcu dependent FOF1-ATPase activity and H+ flux of Escherichia coli at different pHs
During fermentation Escherichia coli transport succinate mainly via Dcu family carriers. Current paper describes the role of externally added...
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ATPase-based implementation of enforced ATP wasting in Saccharomyces cerevisiae for improved ethanol production
BackgroundEnforced ATP wasting has been recognized as a promising metabolic engineering strategy to enhance the microbial production of metabolites...
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Assessing the ATP Binding Ability of NLRP3 from Cell Lysates by a Pull-down Assay
NACHT-, LRR-, and PYD-containing protein 3 (NLRP3) is a member of AAA+ ATPase family that upon activation forms inflammasomes. Several studies...
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Discovery of superior bioactive peptides of two edible Lentinus mushrooms protein hydrolysate in biological activities: tyrosinase inhibitory and antioxidant activity
This study investigated protein hydrolysates obtained from Lentinus squarrosulus and Lentinus edodes fruiting bodies via gastric protease hydrolysis...
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Mechanism of Unidirectional Rotation of γ Subunit in F1-ATPase
In this chapter, the discussion is focused on the functional expression of F1-ATPase, the unidirectional rotation of the γ subunit. In the structure...
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Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity
SLC15A4 is an endolysosome-resident transporter linked with autoinflammation and autoimmunity. Specifically, SLC15A4 is critical for Toll-like...
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Preventive effect of Cleome spinosa against cucumber Fusarium wilt and improvement on cucumber growth and physiology
Cucumber wilt is an important soil borne disease in cucumber production, which seriously affects the development of the cucumber industry. Cleome...
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Transcranial photobiomodulation ameliorates midbrain and striatum neurochemical impairments and behavioral deficits in reserpine-induced parkinsonism in rats
Photobiomodulation (PBM) of deep brain structures through transcranial infrared irradiation might be an effective treatment for Parkinson’s disease...
