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Rational protein engineering of a ketoacids decarboxylase for efficient production of 1,2,4-butanetriol from arabinose
BackgroundLignocellulose, the most abundant non-edible feedstock on Earth, holds substantial potential for eco-friendly chemicals, fuels, and...
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Efficient ilamycins production utilizing Enteromorpha prolifera by metabolically engineered Streptomyces atratus
With the invasion of green tides and the increase of urban green areas worldwide, multimillion tons of Enteromorpha need to be reutilized. In this...
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Advances in the optimization of central carbon metabolism in metabolic engineering
Central carbon metabolism (CCM), including glycolysis, tricarboxylic acid cycle and the pentose phosphate pathway, is the most fundamental metabolic...
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Optimization of soil microbial fuel cell for sustainable bio-electricity production: combined effects of electrode material, electrode spacing, and substrate feeding frequency on power generation and microbial community diversity
BackgroundMicrobial fuel cells (MFCs) are among the leading research topics in the field of alternative energy sources due to their multifunctional...
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Microalgal Biomass: Introduction and Production Methods
Microalgae are a potential feedstock used for the generation of wide range of metabolic byproducts and value-added products. Compared to other plants...
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A Multi-objective Optimization Method for Simulating the Operation of Natural Gas Transport System
The optimization of gas pipeline networks plays a pivotal role in ensuring the efficient and economically viable transportation of natural gas. In...
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Manpower Optimization by Using Plant Simulation in the Automotive Industry
This case study is taken from the production line of a tier-one automotive component supplier that produces fuel injection pumps. The purpose of this...
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Sustainable and high-level microbial production of plant hemoglobin in Corynebacterium glutamicum
BackgroundPlant hemoglobin shows great potential as a food additive to circumvent the controversy of using animal materials. Microbial fermentation...
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Bioprospecting of biosurfactant-producing bacteria for hydrocarbon bioremediation: Optimization and characterization
Biosurfactants have been found capable of replacing synthetic surfactants which include ongoing bioprospecting of biosurfactant-producing bacteria as...
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Application of machine learning and genetic algorithms to the prediction and optimization of biodiesel yield from waste cooking oil
The synthesis and usage of biodiesel have become the focus of extensive research due to the ever-increasing emphasis on the development of...
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Optimization of Pectin Extraction from Lemon Peel Powder by Ohmic Heating Using Full Factorial Design
Ohmic heating-assisted extraction has emerged as an effective method preferred in recent years. This extraction method is affected by experimental...
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Modeling, Sensitivity Analysis, and Optimization of the Methanol-to-Gasoline Process using Artificial Intelligence Methods
AbstractIn this study, the gasoline yield in the methanol-to-gasoline (MTG) process was modeled using artificial neural network (ANN) and...
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Biotechnologies for bulk production of microalgal biomass: from mass cultivation to dried biomass acquisition
Microalgal biomass represents a sustainable bioresource for various applications, such as food, nutraceuticals, pharmaceuticals, feed, and other...
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De novo engineering riboflavin production Bacillus subtilis by overexpressing the downstream genes in the purine biosynthesis pathway
BackgroundBacillus subtilis is widely used in industrial-scale riboflavin production. Previous studies have shown that targeted mutagenesis of the...
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Immobilization of alkaline protease produced by Streptomyces rochei strain NAM-19 in solid state fermentation based on medium optimization using central composite design
This study evaluated Streptomyces rochei strain NAM-19 solid-state fermentation of agricultural wastes to produce alkaline protease. Alkaline...
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Scaling-Up of Cultivated Meat Production Process
Upscaling the production of cultured meat from laboratory flasks to an industrial scale is undeniably a great challenge, yet it is imperative for the...
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Optimization and Modeling of Curdlan Production under Multi-physiological-parameters Process Control by Agrobacterium radiobacter Mutant A-15 at High Initial Glucose
The optimization and kinetic modeling of curdlan synthesis by Agrobacterium radiobacter mutant A-15 under multi-physiological-parameters process...
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Modeling and Optimization of Biodiesel Production from Croton macrostachyus Leaves Oil
The biodiesel produced from Croton macrostachyus (CM) leaves mostly contains unsaturated fatty acid esters with low stability of oxidation. A Croton...
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Improving the production of the micafungin precursor FR901379 in an industrial production strain
BackgroundMicafungin is an echinocandin-type antifungal agent used for the clinical treatment of invasive fungal infections. It is semisynthesized...
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Statistical Optimization and Partial Characterization of Xylanases Produced by Streptomyces sp. S1M3I Using Olive Pomace as a Fermentation Substrate
Xylanase production by Streptomyces sp. S1M3I was optimized by response surface methodology (RSM), followed by a partial characterization of these...
