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Optimization of the production process for the anticancer lead compound illudin M: improving titers in shake-flasks
BackgroundThe fungal sesquiterpenes Illudin M and S are important base molecules for the development of new anticancer agents due to their strong...
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Metabolic flux analysis and metabolic engineering for polyhydroxybutyrate (PHB) production
Metabolic engineering provides a more sustainable alternative by using complex metabolic processes to generate valuable compounds by exploiting...
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Culture Optimization to Produce High Yields of Mycosporine-Like Amino Acids by Fischerella sp. F5
Fischerella sp. is a valuable source of active metabolites, including UV-protecting compounds, among which mycosporin-like amino acids (MAAs) can be...
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Optimization of dark fermentative biohydrogen production from rice starch by Enterobacter aerogenes MTCC 2822 and Clostridium acetobutylicum MTCC 11274
Dark fermentative biohydrogen production (DFBHP) has potential for utilization of rice starch wastewater (RSWW) as substrate. The hydrogen production...
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Development of Pd-immobilized porous polymer catalysts via Bayesian optimization
In this study, a Pd-polymeric porous immobilized catalyst is prepared for the Suzuki–Miyaura coupling reactions by employing a Bayesian optimization...
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Study of the probiotic properties of Lacticaseibacillus casei subsp. casei NCIM 5752 and the optimization of whey-based media for the production of its biomass using response surface methodology
In this study, Lacticaseibacillus casei NCIM 5752, a new isolate has been explored for probiotic properties and has shown significant bile salt...
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Optimization of mature coconut water with calamansi, stevia, and turmeric using mixture design
In the Philippines, the Zero Food Waste Act of 2022 has been proposed with the aim of implementing a system that promotes food waste reduction...
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RSM optimization of biodiesel production by a novel composite of Fe(ΙΙΙ)-based MOF and phosphomolybdic acid
The synthesis of MIL-53 samples and encapsulation process of phosphomolybdic acid were implemented using ultrasound at ambient temperature and...
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Optimization for Engineers
Mathematical optimization is a fundamental and ubiquitous concept in various fields, encompassing mathematics, engineering, economics, and more. It...
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Engineering properties and optimization of the dehulling process for hairless canary seed
This work aimed to determine the engineering properties of hairless canary seeds ( Phalaris canariensis L.) of the variety “CDC Maria” and the optimum...
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Instant Controlled Pressure-Drop (DIC) for Volatile Compound Extraction and Bioethanol Production from Empty Aleppo Pinecones and Eucalyptus Chips: Process Optimization and Statistical Modeling
Several plant species contain volatile compounds extracted as “essential oils” through different technologies. After essential oil extraction, the...
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Construction of Synthetic Microbial Consortium for Violacein Production
Violacein, a purple-colored natural pigment produced by microbes, has anti-microbial, anti-parasitic, and anti-cancer properties. Violacein can be...
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Optimization of Nutraceuticals Extraction
Optimization is the selection of the most efficient system that can resolve and help in attaining the objective functions by designing or operating...
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Process optimized for production of iturin A in biofilm reactor by Bacillus velezensis ND
In this research, to provide an optimal growth medium for the production of iturin A, the concentrations of key amino acid precursors were optimized...
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Capacity Optimization of Hybrid Energy Storage System in Microgrid
A hydrogen fuel station is an infrastructure for commercializing hydrogen energy using fuel cells, especially in the automotive field. Hydrogen,...
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Optimization of C50 Carotenoids Production by Open Fermentation of Halorubrum sp. HRM-150
C 50 carotenoids, as unique bioactive molecules, have many biological properties, including antioxidant, anticancer, and antibacterial activity, and...
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Enhanced production of bacteriocin by Bacillus subtilis ZY05
Bacteriocin-producing strains were isolated from the soil of the rice field, screened out using an agar-well diffusion assay against six indicator...
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Multi-objective Optimization
This chapter presents an introduction to multi-objective optimization. First, the basic concepts are presented, and then several solution approaches...
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Enhanced low-cost lipopeptide biosurfactant production by Bacillus velezensis from residual glycerin
Biosurfactants (BSFs) are molecules produced by microorganisms from various carbon sources, with applications in bioremediation and petroleum...
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Chemical mutagenesis and high throughput media optimization in Tolypocladium inflatum MTCC-3538 leads to enhanced production of cyclosporine A
Diethyl sulphate-based mutagenesis was performed on fungal strain Tolypocladium inflatum MTCC-3538. Two mutant morphotypes MT1-3538 and MT2-3538 were...
