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A label-free aptasensing method for detecting SARS-CoV-2 virus antigen by using dumbbell probe-mediated circle-to-circle amplification
Controlling the spread of pathogen requires an efficient and accurate diagnosis. Compared with nucleic acid and antibody detection, antigen assays...
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Sequence-Optimized mRNA Vaccines Against Infectious Disease
Develo** effective mRNA vaccines poses certain challenges concerning mRNA stability and ability to induce sufficient immune stimulation and...
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Tutorial review on the processing and performance of fabrics with antipathogenic inorganic agents
Functionalized textiles have been increasingly used for enhancing antimicrobial or antiviral (antipathogenic) action. Those pathogens can cause...
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Recent Development in Detection Systems for Human Viral Pathogens from Clinical Samples with Special Reference to Biosensors
Over the last few decades, the emergence and re-emergence of various pathogenic viruses have significantly impacted human health. The continuous rise...
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Influenza Vaccine: An Engineering Vision from Virological Importance to Production
According to data from the World Health Organization (WHO) every year, millions of people are affected by flu. Flu is a disease caused by influenza...
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Establishment of a genetically engineered chicken DF-1 cell line for efficient amplification of influenza viruses in the absence of trypsin
BackgroundThe initial step of influenza infection is binding of the virus to specific sialic acid receptors expressed by host cells. This is followed...
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Nanoparticles at the Stage of Clinical Trials
The search of new therapeutic tools and more intensive development of old ones are required to ensure effective treatment of various diseases. The...
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Rapid and sensitive detection of SARS-CoV-2 virus in human saliva samples using glycan based nanozyme: a clinical study
A highly sensitive colorimetric method (glycan-based nano(e)zyme) was developed for sensitive and rapid detection of the SARS-CoV-2 virus based on...
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Antinutritional Factors and Biological Constraints in the Utilization of Plant Protein Foods
Proteins are the principal supplier of nitrogen for growth, repair and maintenance of tissues and vital physiological functions. Plants produce a...
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Early transcriptomic response of the mycoparasite Sphaerodes mycoparasitica to the mycotoxigenic Fusarium graminearum 3-ADON, the cause of Fusarium head blight
Mycoparasites are an assemblage of biotrophic and necrotrophic fungi that occur on plant pathogenic fungal hosts. Biotrophic mycoparasites are often...
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Polymers for Biosensing Applications in Viral Detection and Diagnosis
Technologies for the detection of viruses that are rapid, precise, portable, and on a wide scale are essential for diagnosing the many viral...
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Polymers as Drugs
Polymeric drugs are defined as polymers that are active pharmaceutical ingredients, i.e., they are neither drug carriers nor prodrugs. In general,...
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Advances and insights in the diagnosis of viral infections
Viral infections are the most common among diseases that globally require around 60 percent of medical care. However, in the heat of the pandemic,...
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Polymeric Materials as Potential Inhibitors Against SARS-CoV-2
Recently discovered SARS-CoV-2 caused a pandemic that triggered researchers worldwide to focus their research on all aspects of this new peril to...
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Reverse Vaccinology for Influenza A Virus: From Genome Sequencing to Vaccine Design
Reverse vaccinology (RV) consists in the identification of potentially protective antigens expressed by any organism starting from genomic...
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Highly efficient production of an influenza H9N2 vaccine using MDCK suspension cells
The use of H9N2 subtype avian influenza vaccines is an effective approach for the control of the virus spread among the poultry, and for the...
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Antibodies expand the scope of angiotensin receptor pharmacology
G-protein-coupled receptors (GPCRs) are key regulators of human physiology and are the targets of many small-molecule research compounds and...
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Yeast display platform technology to prepare oral vaccine against lethal H7N9 virus challenge in mice
BackgroundExisting methods for preparing influenza vaccines pose the greatest challenge against highly pandemic avian influenza H7N9 outbreak in the...
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Synthetic Study of Bio-functional Glycans
The molecular structures responsible for the immune functions of complex glycans were unraveled by synthetic studies. We focused on develo**...