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Correction to: Synthesis and application of stationary phase for DNA-affinity chromatographic analysis of unmodified and antisense oligonucleotide
A Correction to this paper has been published: https://doi.org/10.1007/s00216-021-03544-9 .
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Targeting DNA with Triplexes
Triple helical nucleic acids are generated by the binding of a third oligonucleotide strand within the major groove of duplex DNA or RNA, where it...
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Targeting DNA with Triplexes
Triple helical nucleic acids are generated by the binding of a third oligonucleotide strand within the major groove of duplex DNA or RNA, where it...
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Lateral Flow Hybridization Assay to Determine Transcripts of TEM-Type Beta-Lactamase Genes in Bacteria Resistant to Antibiotics
AbstractA technique for lateral flow hybridization analysis of specific bacterial beta-lactamase mRNAs, including the preparation of a biotinylated...
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Poly-adenine-mediated spherical nucleic acids for interfacial recognition of kanamycin
Kanamycin fluorescence aptasensors were created using a series of di-block oligonucleotide modified gold nanoparticles with various lengths of...
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Enzymatic Preparation of DNA with an Expanded Genetic Alphabet Using Terminal Deoxynucleotidyl Transferase and Its Applications
Efficient preparation of DNA oligonucleotides containing unnatural nucleobases (UBs) that can pair with their cognates to form unnatural base pairs...
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A Novel Detection Method of Fe(II) Based on Nanopore Sensor
AbstractA novel Fe(II) detection method was developed on nanopore platform in this work. The incubation mixture of dumbbell DNA and Bleomycin (BLM)...
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Accessible light-controlled knockdown of cell-free protein synthesis using phosphorothioate-caged antisense oligonucleotides
Controlling cell-free expression of a gene to protein with non-invasive stimuli is vital to the future application of DNA nanodevices and synthetic...
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Optimized Design of Degenerate Primers for PCR Based on DNA or Protein Sequence Comparisons
PCR with degenerate primers can be used to identify the coding sequence of an unknown protein or to detect a genetic variant within a gene family....
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Bridged Nucleic Acids for Therapeutic Oligonucleotides
Recent developments in genetic technologies for genomic analysis, diagnostics, and therapeutics have revolutionary effects on medical science....
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Mesyl Phosphoramidate Oligonucleotides: A New Promising Type of Antisense Agents
This chapter provides an overview of mesyl phosphoramidate oligonucleotides (μ-oligonucleotides), which incorporate mesyl phosphoramidate groups...
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Mesyl Phosphoramidate Oligonucleotides: A New Promising Type of Antisense Agents
This chapter provides an overview of mesyl phosphoramidate oligonucleotides (μ-oligonucleotides), which incorporate mesyl phosphoramidate groups...
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HPLC Retention Behavior of Oligonucleotides on an Anion-Exchange HPLC with a High Concentration of Urea
Roles of short RNA molecules in the emergence process of primitive life-like system and physiological activities have been extensively studied from...
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Activatable MRI probes for the specific detection of bacteria
Activatable fluorescent probes have been successfully used as molecular tools for biomedical research in the last decades. Fluorescent probes allow...
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Stereocontrolled access to thioisosteres of nucleoside di- and triphosphates
Nucleoside diphosphates and triphosphates impact nearly every aspect of biochemistry; however, the use of such compounds as tools or medicinal leads...
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A novel ternary Y-DNA walker amplification strategy designed fluorescence aptasensor based on Au@SiO2@Fe3O4 nanomaterials for ochratoxin A detection
A novel ternary Y-DNA walker amplification strategy designed fluorescence aptasensor based on Au@SiO 2 @Fe 3 O 4 nanomaterials for ultrasensitive and...
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Heteromultivalency enables enhanced detection of nucleic acid mutations
Detecting genetic mutations such as single nucleotide polymorphisms (SNPs) is necessary to prescribe effective cancer therapies, perform genetic...
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One-Step Immunoassay for the Detection of SARS-CoV-2 Nucleocapsid Protein Using Screened Fv-Antibodies
Fv-antibodies against the nucleocapsid protein (NP) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were screened from an Fv-antibody...
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Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo
BackgroundThe polymer-based drug/gene delivery is promising for the treatment of inherent or acquire disease, because of the polymer’s structural...
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Improving aptamer performance: key factors and strategies
Aptamers are functional single-stranded oligonucleotide fragments isolated from randomized libraries by Systematic Evolution of Ligands by...
