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A highly contiguous reference genome assembly for Colletotrichum falcatum pathotype Cf08 causing red rot disease in sugarcane
Among the biotic factors, which affect the productivity and quality of sugarcane, red rot disease caused by the fungal pathogen, Colletotrichum...
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Tuning the Assembly of Bispecific Antibodies by Playing on Differential Polypeptide Chain Molar Ratios
Bispecific antibodies (bsAb) represent the most promising class of therapeutics due to their multiple mode of action. Their development raised...
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The Role of Whole-Genome Methods in the Industrial Production of Value-Added Compounds
The rate of microbial genome sequencing has accelerated with the introduction of high-throughput sequencing technologies and pertinent analytical...
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Draft genome sequencing of halotolerant bacterium Salinicola sp. DM10 unravels plant growth-promoting potentials
In this study, strain DM10 was isolated from mangrove roots and characterized as a halotolerant plant growth-promoting bacterium. Strain DM10...
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CRISPR-Mediated Genome Engineering in Aedes aegypti
CRISPR-mediated genome engineering technologies have been adapted to a wide variety of organisms with high efficiency and specificity. The yellow...
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Complete genome resource unravels the close relation of an Indian Xanthomonas oryzae pv. oryzae strain IXOBB0003 with Philippines strain causing bacterial blight of rice
Xanthomonas oryzae pv. oryzae (Xoo) is a pathogen of concern for rice growers as it limits the production potential of rice varieties worldwide. Due...
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Chloroplast genome skimming of a potential agroforestry species Melia dubia. Cav and its comparative phylogenetic analysis with major Meliaceae members
Melia dubia Cav. is a fast-growing plywood species gaining popularity due to high economic returns. This study aimed to assemble and annotate the...
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Genome-Editing Advances for Disease Resistance in Plants
Global food security relies on agricultural crops, and their yield is affected by various phytopathogens. These phytopathogens are prevented by using...
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Towards DNA-free CRISPR/Cas9 genome editing for sustainable oil palm improvement
The CRISPR/Cas9 genome editing system has been in the spotlight compared to programmable nucleases such as ZFNs and TALENs due to its simplicity,...
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Minimal Cells and Genome Minimization: Top-Down and Bottom-Up Approaches to Construct Synthetic Cells
Bioproduction of high-value molecules has traditionally been carried out using engineered host cells. However, toxic molecules and membrane proteins...
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Unique footprints of balancing selection in bovine genome
Balancing selection is the process of selection that preserves various alleles within a population. Studying the areas undergoing balancing selection...
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Whole genome sequencing and phylogenomic analyses of a novel glufosinate-tolerant Pseudomonas species
A novel glufosinate-tolerant Pseudomonas sp. LA21, was isolated from soil samples of an oil palm plantation with a long history of glufosinate...
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Evaluation of assembly methods combining long-reads and short-reads to obtain Paenibacillus sp. R4 high-quality complete genome
We sequenced the Paenibacillus sp. R4 using Oxford Nanopore Technology (ONT), single molecule real-time (SMRT) technology from Pacific Biosciences...
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Structural Landscape of nsp Coding Genomic Regions of SARS-CoV-2-ssRNA Genome: A Structural Genomics Approach Toward Identification of Druggable Genome, Ligand-Binding Pockets, and Structure-Based Druggability
SARS-CoV-2 has a single-stranded RNA genome (+ssRNA), and synthesizes structural and non-structural proteins (nsps). All 16 nsp are synthesized from...
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Draft genome sequence of Streptomyces sp. KD18, isolated from industrial soil
The present study scrutinizes the presence of Streptomyces strains in the soil sample collected from industrial area of Bahadurgarh (Haryana) India....
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Engineering Escherichia coli for efficient assembly of heme proteins
BackgroundHeme proteins, such as hemoglobin, horseradish peroxidase and cytochrome P450 (CYP) enzyme, are highly versatile and have widespread...
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Exosomes for CRISPR-Cas9 Delivery: The Cutting Edge in Genome Editing
Gene mutation correction was challenging until the discovery of clustered regularly interspaced short palindromic repeats (CRISPR) and...
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Comprehensive Analysis of the Complete Chloroplast Genome of Cinnamomum daphnoides (Lauraceae), An Endangered Island Endemic Plant
Cinnamomum daphnoides (Siebold & Zucc 1846) is a rare and endangered island species with a unique Sino-Japanese distribution pattern. However,...
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Genome-scale transcriptional activation by non-homologous end joining-mediated integration in Yarrowia lipolytica
BackgroundGenome-scale screening can be applied to efficiently mine for unknown genes with phenotypes of interest or special functions. It is also...
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Stimuli-responsive nanoformulations for CRISPR-Cas9 genome editing
The CRISPR-Cas9 technology has changed the landscape of genome editing and has demonstrated extraordinary potential for treating otherwise incurable...
