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Chrysin stimulates UCP1-independent thermogenesis in 3T3-L1 adipocytes and mouse model
Emerging findings suggest that non-shivering thermogenesis in brown and beige adipocytes may effectively stimulate energy expenditure, thereby...
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Bioinformatics Analysis of miR-181a and Its Role in Adipogenesis, Obesity, and Lipid Metabolism Through Review of Literature
The miRNAs regulate various biological processes in the mammalian body system. The role of miR-181a in the development, progression, and expansion of...
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Autophagic Regulation of Adipogenesis Through TP53INP2: Insights from In Silico and In Vitro Analysis
Obesity is an epidemic disease associated with multimorbidity resulting in higher mortality risk. The imbalance between energy storage and...
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Broccoli microgreens juice reduces body weight by enhancing insulin sensitivity and modulating gut microbiota in high-fat diet-induced C57BL/6J obese mice
PurposeThis study aimed to explore the protective effect of broccoli microgreens juice (BMJ) during C57BL/6J mice obesity development.
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Differentiation of placenta-derived MSCs cultured in human platelet lysate: a xenofree supplement
In the last few decades, mesenchymal stem cells (MSCs)-based regenerative therapies in clinical applications have gradually become a hot topic due to...
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The simple method of lipolysis/lipogenesis balance assessment based on 14C isotope: advances and importance of pH control
Our study is devoted to the development of an optimal protocol for lipolysis and lipogenesis assessment using 14C-labeled glucose. We confirmed the...
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Interplay between adipose tissue secreted proteins, eating behavior and obesity
PurposeAdipokines may play an important role in the complex etiology of human obesity and its metabolic complications. Here, we analyzed the...
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Current progress and limitations of research regarding the therapeutic use of adipose-derived stem cells: literature review
BackgroundAdipose tissue has recently become one of the most promising and predominant sources of mesenchymal stem cells owing to its high...
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Regulatory Roles of MicroRNAs in the Pathogenesis of Metabolic Syndrome
Metabolic syndrome refers to a group of several disease conditions together with high glucose triglyceride levels, high blood pressure, lower...
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Postnatal Tamoxifen Exposure Induces Long-Lasting Changes to Adipose Tissue in Adult Mice
Tamoxifen (TAM) is commonly administered to a variety of inducible or conditional transgenic mice that contain Cre recombinase fused with ER. While...
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Cycloastragenol inhibits adipogenesis and fat accumulation in vitro and in vivo through activating Hedgehog signaling
In this study, we investigated the effect of cycloastragenol (CAG), a triterpenoid isolated from Astragalus membranaceus roots, on regulating the...
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In Vitro Screening and Lipid-Lowering Effect of Prickly Pear (Opuntia Ficus-Indica L. Mill.) Fruit Extracts in 3T3-L1 Pre-Adipocytes and Mature Adipocytes
Opuntia ficus-indica fruits have been widely used due to their nutritional composition and beneficial effects on health, particularly against chronic...
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Development of novel human in vitro vascularized adipose tissue model with functional macrophages
Inflammation has been proven significant factor in development of type 2 diabetes. So far, most of the adipose tissue related research has been...
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Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology
Research on white adipose tissue (WAT), which constitutes one-fifth to one-half of the total body mass of a human’s body, has gained more and more...
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Tart cherry (Prunus cerasus L.) dietary supplement modulates visceral adipose tissue CB1 mRNA levels along with other adipogenesis-related genes in rat models of diet-induced obesity
PurposeThere is increasing evidence for the involvement of dietary bioactive compounds in the cross-talk modulation of endocannabinoid system and...
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Key Targets and Molecular Mechanisms of the Fat-soluble Components of Ginseng for Lung Cancer Treatment
Objective: To analyze the regulatory effects and key targets of the fat-soluble components of ginseng in lung cancer. Methods: Gas...
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Bioactive Compounds and Biological Activities of Korean Ginseng (Panax ginseng Meyer)
Panax ginseng is a perennial herb that has been widely used as a medicinal plant in Southeast Asia and recently in Western medicine. It contains...
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Isolation and Characterization of Human Brown Adipocytes
Brown adipose tissue (BAT) is a thermoregulatory fat with energy-consuming properties. The location and heterogeneity of this tissue makes it...
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Anti-adipogenic effects of viscothionin in 3T3-L1 adipocytes and high fat diet induced obesity mice
Viscum album subsp. Coloratum , also known as Korean mistletoe, is a traditional herb that has more recently been used for the treatment of nervine,...
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Phloretin: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology
Phloretin is a dihydrochalcone found in various plant sources such as apples, strawberries, kumquat, pears, honeybush, and sweet tea. Numerous...