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  1. Recent Progress in Microbial Cultivation Techniques

    Recent advances in the improvement of microbial cultivation are reviewed, with emphasis on biochemical engineering techniques as a means of obtaining...
    Enoch Y. Park in Recent Progress of Biochemical and Biomedical Engineering in Japan I
    Chapter

  2. High Rate Production of Hydrogen/Methane from Various Substrates and Wastes

    To treat soluble and solid wastes and recover energy from them, high rate methane fermentation, especially using the UASB (upflow anaerobic sludge...
    Naomichi Nishio, Yutaka Nakashimada in Recent Progress of Biochemical and Biomedical Engineering in Japan I
    Chapter

  3. Advanced Targeting Strategies for Murine Retroviral and Adeno-associated Viral Vectors

    Targeted gene delivery involves broadening viral tropism to infect previously nonpermissive cells, replacing viral tropism to infect a target cell...
    Julie H. Yu, David V. Schaffer in Gene Therapy and Gene Delivery Systems
    Chapter

  4. Nonviral Delivery of Cancer Genetic Vaccines

    The potential use of genetic vaccines to address numerous diseases including cancer is promising, but currently unrealized. Here, we review...
    Steven R. Little, Robert Langer in Gene Therapy and Gene Delivery Systems
    Chapter

  5. Production and Formulation of Adenovirus Vectors

    Adenovirus vectors have attracted considerable interest over the past decade, with ongoing clinical development programs for applications ranging...
    Nedim E. Altaras, John G. Aunins, ... Jayanthi J. Wolf in Gene Therapy and Gene Delivery Systems
    Chapter

  6. Molecular Conjugates

    Molecular conjugates are nanometer-sized entities consisting of synthetic materials (lipids, polycations, targeting agents, and so on) and nucleic...
    Jeremy Heidel, Swaroop Mishra, Mark E. Davis in Gene Therapy and Gene Delivery Systems
    Chapter

  7. Fluorescence Correlation Spectroscopy with Autofluorescent Proteins

    Fluorescence correlation spectroscopy (FCS) is a versatile technique operating at the single-molecule level, that successfully meets many challenges...
    Tobias Kohl, Petra Schwille in Microscopy Techniques
    Chapter

  8. Fish and Shellfish Upgrading, Traceability

    Recognition of the limited biological resources and the increasing environmental pollution has emphasised the need for better utilisation of...
    Fabienne Guérard, Daniel Sellos, Yves Le Gal in Marine Biotechnology I
    Chapter

  9. Stress Induced by Recombinant Protein Production in Escherichia coli

    Strong production of recombinant proteins interferes with cellular processes in many ways. Drainage of precursors and energy urges the cell to...
    Frank Hoffmann, Ursula Rinas in Physiological Stress Responses in Bioprocesses
    Chapter

  10. Roles of Heat-Shock Chaperones in the Production of Recombinant Proteins in Escherichia coli

    Escherichia coli is a versatile organism for the production of recombinant proteins. Often, however, the recombinant protein does not reach its...
    Frank Hoffmann, Ursula Rinas in Physiological Stress Responses in Bioprocesses
    Chapter

  11. Clarification of Interactions among Microorganisms and Development of Co-culture System for Production of Useful Substances

    Co-culture systems containing two microorganisms for the production of useful substances are described. We developed a novel co-culture system...
    Masayuki Taniguchi, Takaaki Tanaka in Recent Progress of Biochemical and Biomedical Engineering in Japan I
    Chapter

  12. Bacterial Capsular Polysaccharide and Sugar Transferases

    Capsular polysaccharides (CPs) of several pathogenic bacteria are thought to be good materials for the development of new therapeutic reagents. These...
    Katsuhide Miyake, Shinji Iijima in Recent Progress of Biochemical and Biomedical Engineering in Japan I
    Chapter

  13. Bacterial Sterilization and Intracellular Protein Release by a Pulsed Electric Field

    Several biotechnological applications of high-voltage pulsed electric field (PEF) are introduced. Electrical breakdown or disruption of a biological...
    Takayuki Ohshima, Masayuki Sato in Recent Progress of Biochemical and Biomedical Engineering in Japan I
    Chapter

  14. Facts and Theories of Induced Organ Regeneration

    Induced organ regeneration is de novo synthesis of a physiological, or nearly physiological, organ at the same anatomical site as the organ that is...
    Ioannis V. Yannas in Regenerative Medicine I
    Chapter

  15. Fatty Acids from Lipids of Marine Organisms: Molecular Biodiversity, Roles as Biomarkers, Biologically Active Compounds, and Economical Aspects

    Because of their characteristic living environments, marine organisms produce a variety of lipids. Fatty acids constitute the essential part of...
    Jean-Pascal Bergé, Gilles Barnathan in Marine Biotechnology I
    Chapter

  16. Marine Microalgae

    Marine microalgae, the largest primary biomass, have been attracting attention as resources for new metabolites and biotechnologically useful...
    Tadashi Matsunaga, Haruko Takeyama, ... Hiroko Yokouchi in Marine Biotechnology I
    Chapter

  17. Inclusion Bodies: Formation and Utilisation

    The efficient in vivo folding of many heterologous proteins is a major bottleneck of high level production in bacterial hosts and simple optimisation...
    Beatrix Fahnert, Hauke Lilie, Peter Neubauer in Physiological Stress Responses in Bioprocesses
    Chapter

  18. Monitoring of Stress Responses

    New developments in the RNA analysis techniques now enable a comprehensive view on the bacterial physiology under bioprocess conditions. The DNA-chip...
    Thomas Schweder, Michael Hecker in Physiological Stress Responses in Bioprocesses
    Chapter

  19. Functional Magnetic Particles for Medical Application

    Magnetic particles for medical applications have been developed by many researchers. Since magnetic particles have unique magnetic features not...
    Masashige Shinkai, Akira Ito in Recent Progress of Biochemical and Biomedical Engineering in Japan II
    Chapter

  20. Analysis and Control of Proteolysis of Recombinant Proteins in Escherichia coli

    Proteolysis is one of the reasons for poor production of recombinant proteins in Escherichia coli. Important properties of E. coli proteases, which...
    Aleksei Rozkov, Sven-Olof Enfors in Physiological Stress Responses in Bioprocesses
    Chapter
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