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Bioprocess Monitoring Using Near-Infrared Spectroscopy
Near-infrared spectroscopy (NIR) is a nondestructive analytical technique that has been used for simultaneous prediction of the concentrations of...
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Metabolic Flux Analysis Based on 13C-Labeling Experiments and Integration of the Information with Gene and Protein Expression Patterns
The recent progress on metabolic systems engineering was reviewed, in particular focusing on the metabolic flux analysis (MFA) based on the...
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Transgenic Birds for the Production of Recombinant Proteins
Transgenic birds were expected to be an excellent transgenic bioreactor for the production of recombinant pharmaceutical proteins. However, the only...
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Vertebrate Limb Regeneration
In this chapter, we have touched upon some of the key processes of vertebrate limb regeneration from the formation of the wound epithelium to pattern...
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Mammalian Fetal Organ Regeneration
The develo** fetus has the remarkable ability to heal dermal skin wounds by regenerating normal epidermis and dermis with restoration of the...
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Regenerative Capacity and the Develo** Immune System
Many components of the vertebrate immune system have evolved with dual, interrelated functions of both protecting injured tissues from infection and...
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Stem Cells in CNS and Cardiac Regeneration
The central nervous system (CNS) and the heart muscle regenerate poorly after injury, yet evidence is mounting that both harbor cells capable of...
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Higher Harmonic Generation Microscopy
Higher harmonic-generation, including second harmonic generation and third harmonic generation, leaves no energy deposition to the interacted matters...
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Plant Cells: Secondary Metabolite Heterogeneity and Its Manipulation
This chapter proposes the concept of rational manipulation of secondary metabolite heterogeneity in plant cell cultures. The heterogeneity of...
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Recent Progress in Microbial Cultivation Techniques
Recent advances in the improvement of microbial cultivation are reviewed, with emphasis on biochemical engineering techniques as a means of obtaining...
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High Rate Production of Hydrogen/Methane from Various Substrates and Wastes
To treat soluble and solid wastes and recover energy from them, high rate methane fermentation, especially using the UASB (upflow anaerobic sludge...
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Gene therapy by virus-like self-spooling toroidal DNA condensates for revascularization of hindlimb ischemia
Peripheral arterial diseases (PAD) have been reported to be the leading cause for limb amputations, and the current therapeutic strategies including...
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Engineered plastic-associated bacteria for biodegradation and bioremediation
The global plastic waste crisis has triggered the development of novel methods for removal of recalcitrant polymers from the environment....
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Gene expression modulation tools for bacterial synthetic biology
Synthetic biology has revolutionized the creation of microbial cell factories for the efficient production of value-added chemicals and materials...
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A computational fluid dynamics study on the optimisation of a circular sedimentation tank using perforated inlet baffles
A numerical study on a circular sedimentation tank was done to investigate the effect of perforated inlet baffles on the efficiency and performance...
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Molecular-Scale Studies on Biopolymers Using Atomic Force Microscopy
The atomic force microscope (AFM) is capable of acquiring a range of structural and physicochemical information on a wide range of biopolymers. The...
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Polymer Genomics
Biological activities of biocompatible synthetic polymers used in drug delivery, gene delivery, vaccine development or biomaterial surface...
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Production and Formulation of Adenovirus Vectors
Adenovirus vectors have attracted considerable interest over the past decade, with ongoing clinical development programs for applications ranging...
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Nonviral Delivery of Cancer Genetic Vaccines
The potential use of genetic vaccines to address numerous diseases including cancer is promising, but currently unrealized. Here, we review...