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miR-338-5p regulated the NF-κB/MAPK pathway to alleviate inflammation and oxidative stress by targeting IL-6 in rats with atrial fibrillation
The aim of this study was to investigate the functional effect of miR-338-5p targeting IL-6 on NF-κB/MAPK pathway-mediated inflammation and oxidative...
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Morin hydrate ameliorates Di-2-ethylhexyl phthalate (DEHP) induced hepatotoxicity in a mouse model via TNF-α and NF-κβ signaling
Di-(2-ethylhexyl) phthalic acid (DEHP) pollutes the environment, and posing a significant risk to human and animal health. Consequently, a successful...
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Deciphering the enhanced translocation of Pb, Ni and Cd from artificially polluted soil to Chrysopogon zizanioides augmented with Bacillus xiamenensis VITMSJ3
The translocation of heavy metals (HMs) from the rhizosphere to plant systems constitutes a fundamental mechanism governing HM uptake. Microbial...
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Unraveling the potential of uninvestigated thermoalkaliphilic lipases by molecular docking and molecular dynamic simulation: an in silico characterization study
Thermoalkaliphilic lipase enzymes are mostly favored for use in the detergent industry. While there has been considerable research on Geobacillus ...
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Functional transcriptome analysis revealed major changes in pathways affecting systems biology of Tharparkar cattle under seasonal heat stress
Heat stress significantly disturbs the production, reproduction, and systems biology of dairy cattle. A complex interaction among biological systems...
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A new halotolerant xylanase from Aspergillus clavatus expressed in Escherichia coli with catalytic efficiency improved by site-directed mutagenesis
Daily agro-industrial waste, primarily cellulose, lignin, and hemicellulose, poses a significant environmental challenge. Harnessing...
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Transcriptomic and metabolomic profiling reveals molecular regulatory network involved in flower development and phenotypic changes in two Lonicera macranthoides varieties
Due to the medicinal importance of the flowers of **anglei type (XL) Lonicera macranthoides , it is important to understand the molecular mechanisms...
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Integrating pan-genome and reverse vaccinology to design multi-epitope vaccine against Herpes simplex virus type-1
Herpes simplex virus type-1 (HSV-1), the etiological agent of sporadic encephalitis and recurring oral (sometimes genital) infections in humans,...
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Natural biosynthesis, pharmacological applications, and sustainable biotechnological production of ornamental plant-derived anthocyanin: beyond colorants and aesthetics
Flowers have long been admired for their aesthetic qualities and have even found their way to be included in the human diet. Among the many chemical...
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A review on strategies for crop improvement against drought stress through molecular insights
The demand for food goods is rising along with the world population growth, which is directly related to the yield of agricultural crops around the...
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Expression of microbial lipase in filamentous fungus Aspergillus niger: a review
Lipase has high economic importance and is widely used in biodiesel, food, detergents, cosmetics, and pharmaceutical industries. The rapid...
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Diosgenin intervention: targeting lipophagy to counter high glucose diet-induced lipid accumulation and lifespan reduction
Diosgenin (DG), a well-known steroidal sapogenin, is abundantly found in the plants of the Dioscoreaceae family and exhibits diverse pharmacological...
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Mixed infection of two mandariviruses identified by high-throughput sequencing in Kinnow mandarin and development of their specific detection using duplex RT-PCR
In the current study, high-throughput sequencing (HTS) was used to identify viruses associated with the Kinnow mandarin ( Citrus reticulata ) plants...
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Enhanced production of lactic acid from pretreated rice straw using co-cultivation of Bacillus licheniformis and Bacillus sonorenesis
Lactic acid (LA) production from sugar mixture derived from lignocellulosic rice straw employing co- culture system of thermotolerant and inhibitor...
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Unlocking the potential of feruloyl esterase from Myceliophthora verrucosa: a key player in efficient conversion of biorefinery-relevant pretreated rice straw
The lignocellulolytic accessory enzyme, Feruloyl esterase C (FE_5DR), encoded in the genome of thermotolerant Myceliophthora verrucosa was...
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Optimizing laccase selection for enhanced outcomes: a comprehensive review
Despite their widespread applications in sectors such as pulp and paper, textile, food and beverage, pharmaceuticals, and biofuel production,...
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Towards DNA-free CRISPR/Cas9 genome editing for sustainable oil palm improvement
The CRISPR/Cas9 genome editing system has been in the spotlight compared to programmable nucleases such as ZFNs and TALENs due to its simplicity,...
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Recent advancements in the physiological, genetic, and genomic research on Rhododendrons for trait improvement
High species diversity, hybridization potential, broad geographical dispersal range and ornamental characteristics (i.e., attractive size, shape,...
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Use of hydroxyapatite as a support in the immobilization of Thermomyces lanuginosus lipase for application in the production of biodiesel using a by-product as lipid raw material
The use of new materials in the field of biofuel production has been represented as a step in the development of remarkable catalysts. The use of...
