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Synthetic Studies on Heterocyclic Antibiotics Containing Nitrogen Atoms
A variety of heterocyclic antibiotics and phytotoxins have been found to date. Total and semi-synthesis of these natural products and related...
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Strategies for the Synthesis of Manzamine Alkaloids
Recent advances in strategies for the synthesis of manzamine-related alkaloids are summarized and discussed. We particularly focus on strategies...
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A Frontier in Indole Chemistry: 1-Hydroxyindoles, 1-Hydroxytryptamines, and 1-Hydroxytryptophans
Many new members of the 1-hydroxyindole, -tryptamine, and -tryptophan families are prepared. They demonstrate totally different reactivities from...
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Synthesis of Heterocycles Using Polymer-Supported Reagents under Microwave Irradiation
In this chapter, the microwave-assisted synthesis of heterocyclic systems using polymer-supported reagents is reviewed. After a brief introduction...
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Synthesis of Marine Natural Productswith Bicyclic and/or Spirocyclic Acetals
A large number of marine natural products with bicyclic and/or spirocyclic acetals have been found to date. These compounds are usually...
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Conformational Aspects and Interaction Studies of Heterocyclic Drugs
Drug discoveries require the iterative synthesis—along with structural studies—of numerous individual analogues of biologically and medicinally...
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Total Synthesis of Medium-Ring Ethers from Laurencia Red Algae
Medium-ring ethers, specifically those produced by the marine genus Laurencia, have attracted the attention of many synthetic chemists since 1965,...
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Heterocycles from Cyanobacteria
Targets of cyanobacterial heterocyclic cytotoxins classify into tubulin, actin, and the sodium channel. In addition, cyanobacteria produce...
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New Trends in Hexacoordinated Phosphorus Chemistry
Phosphorus derivatives with six substituents at the immediate periphery of the heteroatom are quite common, more than usually imagined, and this...
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Ribosomal RNA Recognition by Aminoglycoside Antibiotics
2-Deoxystreptamine (2-DOS) aminoglycosides are a family of structurally related broad-spectrum antibiotics that are used widely in the clinic. Their...
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Fluorescence Recovery after Photobleaching: Application to Nuclear Proteins
Fluorescence redistribution after photobleaching (FRAP) has received increasing attention ever since it was first introduced into cell biological...
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New Trends in Ylide Chemistry
This review concerns in the first part the works published during the last three years on the synthesis and reactivity of stabilized ylides...
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Polyphosphazenes: A Review
In this paper the synthesis, properties and applications of poly(organophosphazenes) have been highlighted. Five different classes of macromolecules...
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6-Hydrazinonicotinamide Derivatives as Bifunctional Coupling Agents for 99mTc-Labeling of Small Biomolecules
99mTc-labeled small biomolecules are a class of receptor-based, target specific radiopharmaceuticals for the detection of various diseases, such as...
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Trends and Challenges in Enzyme Technology
Several major developments took place in the field of biocatalysis over the past few years. These include the invention of directed evolution...
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Microbial Isoprenoid Production: An Example of Green Chemistry through Metabolic Engineering
Saving energy, cost efficiency, producing less waste, improving the biodegradability of products, potential for producing novel and complex...
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Large-Scale Production of Hairy Root
Many products of interest are synthesized in organized tissues, but not formed in suspension or callus culture. Therefore, most attention has been...
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Functional, Discrete, Nanoscale Supramolecular Assemblies
The last decade has witnessed an unprecedented pursuit of discrete, nanoscale supramolecular aggregates, built by modern methods of self-assembly...
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Evolutionary Potential and Requirements for Minimal Protocells
Minimal protocell concepts have high intellectual and practical value. Following chemoton theory, developed by Tibor Gánti in 1971, we suggest that...
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Self-Assembly DNA-Conjugated Polymer for DNA Immobilization on Chip
DNA chips are extensively used for genome and transcriptome analyses in the post-genomic sequence era. A self-assembly technique can be applied to...