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Impact of hepatic inflammation and fibrosis on the recurrence and long-term survival of hepatitis B virus-related hepatocellular carcinoma patients after hepatectomy
BackgroundUnderlying liver disease is correlated with hepatocellular carcinoma (HCC) development in patients with hepatitis B virus (HBV) infection....
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Pseudotyped Virus for Papillomavirus
Papillomavirus is difficult to culture in vitro, which limits its related research. The development of pseudotyped virus technology provides a... -
Impact of preoperative antiviral therapy on the prognosis of hepatitis B virus-related hepatocellular carcinoma
BackgroundFor chronic hepatitis B virus (HBV) infection patients, increasing evidence has demonstrated the effectiveness of expanding the indications...
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Structure of monkeypox virus poxin: implications for drug design
Monkeypox, or mpox, is a disease that has recently resurfaced and spread across the globe. Despite the availability of an FDA-approved vaccine...
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Prognostic potential of preoperative circulating tumor cells to predict the early progression recurrence in hepatocellular carcinoma patients after hepatectomy
BackgroundThe role of circulating tumor cells (CTCs) in prognosis prediction has been actively studied in hepatocellular carcinoma (HCC) patients....
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The role of oncolytic virotherapy and viral oncogenes in the cancer stem cells: a review of virus in cancer stem cells
Cancer Stem Cells (CSCs) are the main “seeds” for the initiation, growth, metastasis, and recurrence of tumors. According to many studies, several...
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Can prophylactic HPV vaccination reduce the recurrence of cervical lesions after surgery? Review and prospect
Women with HSIL typically undergo conization/LEEP to remove cervical lesions, but the risk of HSIL lesions returning after surgical treatment remains...
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Does depressurization of the portal vein before liver transplantation affect the recurrence of HCC? A nested case-control study
BackgroundPortal hypertension (PHT) has been proven to be closely related to the development of hepatocellular carcinoma (HCC). Whether PHT before...
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Serum NY-ESO-1 antibody as a predictive biomarker for postoperative recurrence of gastric cancer: a multicenter prospective observational study
BackgroundNo reliable marker has been identified to predict postoperative recurrence of gastric cancer. We designed a clinical trial to investigate...
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Efficacy of salvage surgery versus re-irradiation for isolated regional lymph node recurrence in patients with nasopharyngeal carcinoma
BackgroundTo compare the clinical characteristics and prognoses of patients with isolated regional lymph node recurrent nasopharyngeal carcinoma...
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Tenofovir versus entecavir on decreasing risk of HBV-related hepatocellular carcinoma recurrence after liver transplantation
BackgroundRecent studies have proved that tenofovir disoproxil fumarate (TDF) is associated with a lower risk of hepatocellular carcinoma (HCC)...
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The role of adjuvant transcatheter arterial chemoembolization following repeated curative resection/ablation for hepatocellular carcinoma with early recurrence: a propensity score matching analysis
BackgroundThe role of adjuvant transcatheter arterial chemoembolization (TACE) following repeated resection/ablation for recurrent hepatocellular...
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Early and late recurrence after hepatectomy in patients with low-level HBV-DNA hepatocellular carcinoma under antiviral therapy
BackgroundAntiviral therapy has been shown to benefit long-term survival after curative hepatectomy in patients with hepatitis B virus...
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Development and validation of a multivariable model for prediction of malignant transformation and recurrence of oral epithelial dysplasia
BackgroundOral epithelial dysplasia (OED) is the precursor to oral squamous cell carcinoma which is amongst the top ten cancers worldwide. Prognostic...
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MET exon 14 skip** mutation drives cancer progression and recurrence via activation of SMAD2 signalling
Backgroundc-Met encoded by the proto-oncogene MET, also known as hepatocyte growth factor (HGF) receptor, plays a crucial role in cellular processes....
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Enhancing cancer therapy: the integration of oncolytic virus therapy with diverse treatments
As one of the significant challenges to human health, cancer has long been a focal point in medical treatment. With ongoing advancements in the field...
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Using immunovascular characteristics to predict very early recurrence and prognosis of resectable intrahepatic cholangiocarcinoma
ObjectiveTo predict the very early recurrence (VER) of patients with intrahepatic cholangiocarcinoma (ICC) based on TLSs and MVI status, and further...
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Autophagy, molecular chaperones, and unfolded protein response as promoters of tumor recurrence
Tumor recurrence is a paradoxical function of a machinery, whereby a small proportion of the cancer cell population enters a resistant, dormant...
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A liquid biopsy signature for predicting early recurrence in patients with gastric cancer
BackgroundGastric cancer (GC) patients who experience recurrence within the first year following surgery (early recurrence [ER]) exhibit worse...
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Repurposing of Zika virus live-attenuated vaccine (ZIKV-LAV) strains as oncolytic viruses targeting human glioblastoma multiforme cells
Glioblastoma multiforme (GBM) is the most common malignant primary brain cancer affecting the adult population. Median overall survival for GBM...