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Promoting oral absorption of Panax notoginseng saponins via thiolated trimethyl chitosan and wheat germ agglutinin–modified nanoformulation
This study aimed to enhance the oral absorption of Panax notoginseng saponins (PNS) via nanoparticles modified with thiolated trimethyl chitosan...
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Immunological Assessment of Chitosan or Trimethyl Chitosan-Coated PLGA Nanospheres Containing Fusion Antigen as the Novel Vaccine Candidates Against Tuberculosis
The crucial challenge in tuberculosis (TB) as a chronic infectious disease is to present a novel vaccine candidate that improves current vaccination...
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Chitosan-Based Nanocomposite as Targeted Drug Delivery Carrier
Chitosan, a biopolymer, has versatile physicochemical and biological/pharmacological properties which are treasury for the pharmaceutical field....
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Chitosan-based drug delivery systems for skin atopic dermatitis: recent advancements and patent trends
Atopic dermatitis (AD) is a complex, relapsing inflammatory skin disease with a considerable social and economic burden globally. AD is primarily...
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Chitosan-Based Gels for Ocular Drug Delivery
Ocular drug delivery presents challenges to researchers due to the complexity of the eye as an organ. Different layers of barriers and other...
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Chitosan and Chitooligosaccharides: Preparation, Characteristics, and Their Potential Application as Therapeutic Agents
Chitosan is one of the marine biomaterials widely found in crustacean, insect, arachnids, and fungi as the deacetylation product of chitin. Due to...
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RETRACTED ARTICLE: Codelivery of HIF-1α siRNA and Dinaciclib by Carboxylated Graphene Oxide-Trimethyl Chitosan-Hyaluronate Nanoparticles Significantly Suppresses Cancer Cell Progression
PurposeHypoxia-inducible factor (HIF) is one of the critical components of the tumor microenvironment that is involved in tumor development. HIF-1α...
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Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment
The study describes the current state of knowledge on nanotechnology and its utilization in medicine. The focus in this manuscript was on the...
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An overview of chitosan and its application in infectious diseases
Infectious diseases, such as the coronavirus disease-19, SARS virus, Ebola virus, and AIDS, threaten the health of human beings globally. New...
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Potential Biomedical Applications of Marine Sponge-Derived Chitosan: Current Breakthroughs in Drug Delivery for Wound Care
In recent years, there has been enormous search and demand for naturally sourced polymers and excipients in the healthcare sector. Chitosan is a very...
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RETRACTED ARTICLE: Dual Blockade of PD-1 and LAG3 Immune Checkpoints Increases Dendritic Cell Vaccine Mediated T Cell Responses in Breast Cancer Model
PurposeIncreasing the efficiency of unsuccessful immunotherapy methods is one of the most important research fields. Therefore, the use of...
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Fabrication Technology of Chitosan-Based IPN: Drug Delivery Application
Chitosan as a biocompatible and biodegradable polymer is a good candidate for preparation of interpenetrating polymer network (IPN) hydrogel with...
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Engineering the pH-Sensitivity of the Graphene and Carbon Nanotube Based Nanomedicines in Smart Cancer Therapy by Grafting Trimetyl Chitosan
PurposeThe aim of this study was to introduce a smart and responsive drug carrier for Doxorubicin (DOX) and Paclitaxel (PAX) for desirable...
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Chitosan-based particulate systems for drug and vaccine delivery in the treatment and prevention of neglected tropical diseases
Neglected tropical diseases (NTDs) are a diverse group of infections which are difficult to prevent or control, affecting impoverished communities...
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Marine Polysaccharides in Pharmaceutical Uses
Marine offers varied ingenious biomolecules, like polyethers, lipoglycoproteins, and polysaccharides executing native bio-functions including...
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Chitosan-Raloxifene nanoparticle containing doxorubicin as a new double-effect targeting vehicle for breast cancer therapy
Backgroundtreatment of breast cancer as one of the most common cancers in the world remains an important area of drug development based on...
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Chitin and Its Derivatives
Chitin and chitosan are well-known natural polymers that have been considered a sustainable feedstock for the production of high-value biomaterials....
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Marine Biopolymers for Gene Delivery
The marine ecosystem species biodiversity including algae, crustacean, and plant offers biopolymers such as chitin, chitosan, alginate, gelatin,...
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Nutraceutical-Loaded Chitosan Nanoparticles for Healthcare Applications
Nutraceutical, a combination term of nutrition and pharmaceutical, refers to a wide variety of products including food and food-derived substances...