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Feasibility study of volumetric modulated arc therapy with Halcyon™ linac for total body irradiation
BackgroundThe use of total body irradiation (TBI) with linac-based volumetric modulated arc therapy (VMAT) has been steadily increasing. Helical...
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Partial-Volume Irradiation of Murine Tumors
Radiotherapy is a widely used approach for cancer treatment. However, delivering a single high dose of radiation to bulky tumors can be challenging...
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The Effects of Whole Body Gamma Irradiation on Mice, Age-Related Behavioral, and Pathophysiological Changes
We designed a study with the objective to determine the long-term radiation effects of gamma rays, originating from a single shot of Co 60 at a dose...
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Impact of chronic graft-versus-host disease on quality of life and cognitive function of long-term transplant survivors after allogeneic hematopoietic stem cell transplantation with total body irradiation
BackgroundTotal body irradiation (TBI)-based-conditioning before allogeneic hematopoietic stem cell transplantation (allo-HSCT) is standard of care...
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Exosomes are involved in total body irradiation-induced intestinal injury in mice
Ionizing radiation-induced intestinal injury is a catastrophic complication in patients receiving radiotherapy. Circulating exosomes from patients...
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Preclinical validation and treatment of volumetric modulated arc therapy based total bone marrow irradiation in Halcyon™ ring gantry linear accelerator
AimThis study aims to report preclinical validation, and the first clinical treatment of total bone marrow irradiation (TMI) and total bone marrow...
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Fractionated whole body γ-irradiation aggravates arthritic severity via boosting NLRP3 and RANKL expression in adjuvant-induced arthritis model: the mitigative potential of ebselen
Rheumatoid arthritis (RA) is an autoimmune chronic inflammatory disease associated with oxidative stress that causes excruciating pain, discomfort,...
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A bi-institutional multi-disciplinary failure mode and effects analysis (FMEA) for a Co-60 based total body irradiation technique
BackgroundWe aim to assess the risks associated with total body irradiation (TBI) delivered using a commercial dedicated Co-60 irradiator, and to...
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Studies on the effect of curcumin and quercetin in the liver of male albino rats exposed to gamma irradiation
Ionizing radiation produces deleterious effects on living organisms. The present investigation has been carried out to study the prophylactic as well...
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Cranial irradiation disrupts homeostatic microglial dynamic behavior
Cranial irradiation causes cognitive deficits that are in part mediated by microglia, the resident immune cells of the brain. Microglia are highly...
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Post-Irradiation Recovery of B14-150 Fibrosarcoma Cells after Combined Irradiation with Low and High Linear Energy Transfer
The use of radiation with low and high linear energy transfer (LET) in the same treatment regimen is promising in terms of increasing the efficiency...
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Technical note: factors affecting dose distribution in the overlap region of two-segment total body irradiation by helical tomotherapy
ObjectiveTo assess the effects of various treatment planning parameters to identify the optimal gap distance for precise two-segment total body...
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Vertebral body and splenic irradiation are associated with lymphopenia in localized pancreatic cancer treated with stereotactic body radiation therapy
ObjectivesThe purpose of this study was to determine if vertebral body and splenic dosimetry was associated with the development of lymphopenia in...
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Total body irradiation in Australia and New Zealand: results of a practice survey
Total body irradiation (TBI) is an important treatment modality for the preparation of patients for bone marrow transplants. It is technically...
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The Conversion and Degradation of Sulphaguanidine under UV and Electron Beam Irradiation Using Fluorescence
The work presents a spectral-luminescent study of the sulfaguanidine transformation in water under a pulsed e-beam and UV irradiation of an UVb-04...
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Lactoferrin Has a Protective Effect on Mouse Brain Cells after Acute Gamma Irradiation of the Head
We studied the effect of human lactoferrin on cells of the hippocampal dentate gyrus of 2-2.5-month-old male C57BL/6 mice after acute gamma...
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Blue light irradiation inhibits the M2 polarization of the cancer-associated macrophages in colon cancer
Recent studies have shown that blue light-emitting diode (LED) light has anti-tumor effects, suggesting the possibility of using visible light in...
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Assessing the Association of the Degree of DNA Methylation and the Frequency of Chromosomal Aberrations in Human Lymphocytes in a Single Irradiation of Blood In Vitro
AbstractThe most sensitive biomolecule under radiation exposure is DNA, whose damage manifests itself in the form of chromosomal aberrations (CA)....
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Effect of anti-scatter grids on the image improvement factor in digital radiography for various phantom thicknesses and irradiation fields
Digital radiography (DR) is used to acquire digital images with a consistent image brightness under different exposures and in the presence of...
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Current practices of craniospinal irradiation techniques in Turkey: a comprehensive dosimetric analysis
ObjectiveThis study evaluates various craniospinal irradiation (CSI) techniques used in Turkish centers to understand their advantages, disadvantages...
